(Q82951867)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21170050%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Mapping the sequence of conformational changes underlying selectivity filter gating in the K(v)11.1 potassium channel (English)

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18 January 2020

5

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18 January 2020

author name string

David T Wang

1

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18 January 2020

Adam P Hill

2

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18 January 2020

Stefan A Mann

3

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18 January 2020

Peter S Tan

4

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18 January 2020

publication date

19 December 2010

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Nature Structural & Molecular Biology

18 January 2020

published in

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18 January 2020

volume

18

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18 January 2020

issue

1

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18 January 2020

page(s)

35-41

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https://scigraph.springernature.com/pub.10.1038/nsmb.1966

18 January 2020

exact match

0 references

cites work

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 reference

The voltage-gated potassium channels and their relatives

31 March 2020

1 reference

A gate in the selectivity filter of potassium channels

31 March 2020

1 reference

Dynamic personalities of proteins

31 March 2020

1 reference

Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels

31 March 2020

1 reference

Structural mechanism of C-type inactivation in K(+) channels

31 March 2020

1 reference

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

31 March 2020

1 reference

From the first protein structures to our current knowledge of protein folding: delights and scepticisms

31 March 2020

1 reference

Quantitative analysis of structure–activity relationships in engineered proteins by linear free-energy relationships

31 March 2020

1 reference

The folding of an enzyme. I. Theory of protein engineering analysis of stability and pathway of protein folding

31 March 2020

1 reference

Relationship of Leffler (Bronsted) alpha values and protein folding Phi values to position of transition-state structures on reaction coordinates

31 March 2020

1 reference

Mapping the conformational wave of acetylcholine receptor channel gating

31 March 2020

1 reference

A stepwise mechanism for acetylcholine receptor channel gating

31 March 2020

1 reference

Phi-value analysis of a linear, sequential reaction mechanism: theory and application to ion channel gating

31 March 2020

1 reference

hERG potassium channels and cardiac arrhythmia

31 March 2020

1 reference

Drug binding to the inactivated state is necessary but not sufficient for high-affinity binding to human ether-à-go-go-related gene channels

31 March 2020

1 reference

The inward rectification mechanism of the HERG cardiac potassium channel

31 March 2020

1 reference

The pore domain outer helix contributes to both activation and inactivation of the HERG K+ channel.

31 March 2020

1 reference

Structural and functional role of the extracellular s5-p linker in the HERG potassium channel

31 March 2020

1 reference

Regional specificity of human ether-a'-go-go-related gene channel activation and inactivation gating.

31 March 2020

1 reference

Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation

31 March 2020

1 reference

A mutation in the pore region of HERG K+ channels expressed in Xenopus oocytes reduces rectification by shifting the voltage dependence of inactivation.

31 March 2020

1 reference

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

31 March 2020

1 reference

A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes

31 March 2020

1 reference

Na+ permeation and block of hERG potassium channels

31 March 2020

1 reference

Cellular mechanism of aminoglycoside tolerance in long-term gentamicin treatment

31 March 2020

1 reference

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

31 March 2020

1 reference

Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels

31 March 2020

1 reference

Molecular driving forces determining potassium channel slow inactivation

31 March 2020

1 reference

Dynamic rearrangement of the outer mouth of a K+ channel during gating

31 March 2020

1 reference

Structure of the transition state of gating in the acetylcholine receptor channel pore: a phi-value analysis.

31 March 2020

1 reference

An engineered cysteine in the external mouth of a K+ channel allows inactivation to be modulated by metal binding

31 March 2020

1 reference

Structure-activity relationships in engineered proteins: analysis of use of binding energy by linear free energy relationships

31 March 2020

1 reference

Transition states and the meaning of Phi-values in protein folding kinetics

31 March 2020

1 reference

Structural basis for the coupling between activation and inactivation gates in K(+) channels

31 March 2020

1 reference

The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a'-go-go-related gene (hERG) K+ channel.

31 March 2020

1 reference

Coupling of activation and inactivation gate in a K+-channel: potassium and ligand sensitivity

31 March 2020

1 reference

Modulation of K+ current by frequency and external [K+]: a tale of two inactivation mechanisms.

31 March 2020

1 reference

Molecular determinants of gating at the potassium-channel selectivity filter

31 March 2020

1 reference

Use-dependent blockers and exit rate of the last ion from the multi-ion pore of a K+ channel

31 March 2020

1 reference

Functional consequences of a decreased potassium affinity in a potassium channel pore. Ion interactions and C-type inactivation

31 March 2020

1 reference

The open pore conformation of potassium channels

31 March 2020

1 reference

How to turn the reaction coordinate into time

31 March 2020

1 reference

Gating currents associated with intramembrane charge displacement in HERG potassium channels

31 March 2020

1 reference

Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel

31 March 2020

1 reference

Aromatic Residues {epsilon}Trp-55 and {delta}Trp-57 and the Activation of Acetylcholine Receptor Channels

31 March 2020

1 reference

Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels

31 March 2020

1 reference

A structural interpretation of voltage-gated potassium channel inactivation.

31 March 2020

1 reference

A conserved glutamate is important for slow inactivation in K+ channels.

31 March 2020

1 reference

Cross talk between activation and slow inactivation gates of Shaker potassium channels

31 March 2020

1 reference

Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype

31 March 2020

1 reference

Temperature dependence of human ether-a-go-go-related gene K+ currents.

31 March 2020

1 reference

Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels

31 March 2020

1 reference

12 December 2020

Single HERG delayed rectifier K+ channels expressed in Xenopus oocytes.

1 reference

12 December 2020

The HERG K+ channel: progress in understanding the molecular basis of its unusual gating kinetics

1 reference

12 December 2020

Pathways of HERG inactivation.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NSMB.1966

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21170050%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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