(Q82984034)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19085994%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Evolution of tertiary carbinamine BACE-1 inhibitors: Abeta reduction in rhesus CSF upon oral dosing (English)

1 reference

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18 January 2020

5

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18 January 2020

author name string

Philippe G Nantermet

1

1 reference

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18 January 2020

Hemaka A Rajapakse

2

1 reference

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18 January 2020

Mathew G Stanton

3

1 reference

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18 January 2020

Shaun R Stauffer

4

1 reference

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18 January 2020

Allison R Gregro

6

1 reference

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18 January 2020

Keith P Moore

7

1 reference

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18 January 2020

Melissa A Steinbeiser

8

1 reference

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18 January 2020

John Swestock

9

1 reference

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18 January 2020

Harold G Selnick

10

1 reference

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18 January 2020

Samuel L Graham

11

1 reference

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18 January 2020

Georgia B McGaughey

12

1 reference

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18 January 2020

Dennis Colussi

13

1 reference

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18 January 2020

Ming-Tain Lai

14

1 reference

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18 January 2020

Sethu Sankaranarayanan

15

1 reference

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18 January 2020

Adam J Simon

16

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18 January 2020

Sanjeev Munshi

17

1 reference

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18 January 2020

Jacquelynn J Cook

18

1 reference

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18 January 2020

Marie A Holahan

19

1 reference

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18 January 2020

Maria S Michener

20

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18 January 2020

Joseph P Vacca

21

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18 January 2020

publication date

1 January 2009

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18 January 2020

1 reference

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18 January 2020

volume

4

1 reference

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18 January 2020

issue

1

1 reference

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18 January 2020

page(s)

37-40

1 reference

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Alzheimer's disease and Parkinson's disease

18 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Alzheimer disease: mechanistic understanding predicts novel therapies

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Pathways towards and away from Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Pharmacological strategies for the prevention of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Alzheimer's disease one century later: The search for effective therapeutic targets continues

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Shutting down Alzheimer's.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

https://api.crossref.org/works/10.1002%2FCMDC.200800308

1 reference

7 January 2021

A century of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Protease inhibitors as potential disease-modifying therapeutics for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Development of BACE1 inhibitors for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Classification analysis of P-glycoprotein substrate specificity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Discovery of oxadiazoyl tertiary carbinamine inhibitors of beta-secretase (BACE-1)

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Discovery of isonicotinamide derived beta-secretase inhibitors: in vivo reduction of beta-amyloid

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Beta-secretase (BACE-1) inhibitors: accounting for 10s loop flexibility using rigid active sites

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Novel mutations introduced at the beta-site of amyloid beta protein precursor enhance the production of amyloid beta peptide by BACE1 in vitro and in cells.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Evaluation of drug interactions with P-glycoprotein in drug discovery: in vitro assessment of the potential for drug-drug interactions with P-glycoprotein

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

CSF as a surrogate for assessing CNS exposure: an industrial perspective

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Inhibitors of HIV-1 protease: 10 years after

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Inhibitors of HIV-1 protease: current state of the art 10 years after their introduction. From antiretroviral drugs to antifungal, antibacterial and antitumor agents based on aspartic protease inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200800308

7 January 2021

Identifiers

DOI

10.1002/CMDC.200800308

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19085994%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference