(Q83010552)

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18 January 2020

title

How subunits cooperate in cAMP-induced activation of homotetrameric HCN2 channels (English)

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18 January 2020

1

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18 January 2020

Klaus Benndorf

9

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18 January 2020

5

Vasilica Nache

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18 January 2020

2

Susanne Thon

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18 January 2020

8

Frank Schwede

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18 January 2020

author name string

Eckhard Schulz

3

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18 January 2020

Christoph Biskup

4

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18 January 2020

Thomas Zimmer

6

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18 January 2020

Reinhard Seifert

7

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18 January 2020

publication date

18 December 2011

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18 January 2020

published in

Nature Chemical Biology

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18 January 2020

volume

8

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18 January 2020

page(s)

162-169

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18 January 2020

issue

2

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https://scigraph.springernature.com/pub.10.1038/nchembio.747

18 January 2020

exact match

0 references

cites work

How does adrenaline accelerate the heart?

1 reference

12 December 2020

Structural basis for modulation and agonist specificity of HCN pacemaker channels

1 reference

12 December 2020

Interdependence of receptor activation and ligand binding in HCN2 pacemaker channels.

1 reference

12 December 2020

Molecular mechanism of cAMP modulation of HCN pacemaker channels.

1 reference

12 December 2020

Molecular mechanism of cyclic-nucleotide-gated channel activation

1 reference

12 December 2020

Characterization of single pacemaker channels in cardiac sino-atrial node cells

1 reference

12 December 2020

Hyperpolarization-activated cation current (Ih) in neurons of the medial nucleus of the trapezoid body: voltage-clamp analysis and enhancement by norepinephrine and cAMP suggest a modulatory mechanism in the auditory brain stem.

1 reference

12 December 2020

Hill coefficient for estimating the magnitude of cooperativity in gating transitions of voltage-dependent ion channels

1 reference

12 December 2020

Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens

1 reference

12 December 2020

Relating ligand binding to activation gating in CNGA2 channels.

1 reference

12 December 2020

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain

1 reference

12 December 2020

Pacemaker oscillations in heart and brain: a key role for hyperpolarization-activated cation channels

1 reference

12 December 2020

Activity-dependent regulation of HCN pacemaker channels by cyclic AMP: signaling through dynamic allosteric coupling

1 reference

12 December 2020

Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channels

1 reference

12 December 2020

A family of hyperpolarization-activated mammalian cation channels

1 reference

12 December 2020

Differential distribution of four hyperpolarization-activated cation channels in mouse brain

1 reference

12 December 2020

Patch-clamp fluorometry recording of conformational rearrangements of ion channels

1 reference

12 December 2020

Integrated allosteric model of voltage gating of HCN channels

1 reference

12 December 2020

Modulation of a presynaptic hyperpolarization-activated cationic current (I(h)) at an excitatory synaptic terminal in the rat auditory brainstem

1 reference

12 December 2020

The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels

1 reference

12 December 2020

Two pacemaker channels from human heart with profoundly different activation kinetics

1 reference

12 December 2020

Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS.

1 reference

12 December 2020

Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels

1 reference

12 December 2020

The Hill equation revisited: uses and misuses.

1 reference

12 December 2020

Activation of olfactory-type cyclic nucleotide-gated channels is highly cooperative.

1 reference

12 December 2020

Excitability increase induced by beta-adrenergic receptor-mediated activation of hyperpolarization-activated cation channels in rat cerebellar basket cells

1 reference

12 December 2020

Hyperpolarization-activated cation channels: from genes to function

1 reference

12 December 2020

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

1 reference

12 December 2020

HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons.

1 reference

12 December 2020

Regulation of hyperpolarization-activated HCN channels by cAMP through a gating switch in binding domain symmetry

1 reference

12 December 2020

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

1 reference

12 December 2020

Kinetic relationship between the voltage sensor and the activation gate in spHCN channels

1 reference

12 December 2020

Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers.

1 reference

12 December 2020

Dual allosteric modulation of pacemaker (f) channels by cAMP and voltage in rabbit SA node.

1 reference

12 December 2020

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

1 reference

12 December 2020

Molecular diversity of pacemaker ion channels

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12 December 2020

Modulation of the hyperpolarization-activated current (Ih) by cyclic nucleotides in guinea-pig primary afferent neurons.

1 reference

12 December 2020

Inactivation in HCN channels results from reclosure of the activation gate: desensitization to voltage

1 reference

12 December 2020

Regulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regions

1 reference

12 December 2020

Hyperpolarization-activated cation currents: from molecules to physiological function

1 reference

12 December 2020

CNG and HCN channels: two peas, one pod.

1 reference

12 December 2020

Hysteresis in the voltage dependence of HCN channels: conversion between two modes affects pacemaker properties

1 reference

12 December 2020

Molecular identification of a hyperpolarization-activated channel in sea urchin sperm

1 reference

12 December 2020

Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain

1 reference

12 December 2020

Gating rearrangements in cyclic nucleotide-gated channels revealed by patch-clamp fluorometry.

1 reference

12 December 2020

State-dependent cAMP binding to functioning HCN channels studied by patch-clamp fluorometry

1 reference

12 December 2020

Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.747

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18 January 2020

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