(Q83181178)

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The genetic stability of a conditional live HIV-1 variant can be improved by mutations in the Tet-On regulatory system that restrain evolution

scientific article published on 20 April 2006

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19 January 2020

The genetic stability of a conditional live HIV-1 variant can be improved by mutations in the Tet-On regulatory system that restrain evolution (English)

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19 January 2020

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Bep Klaver

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19 January 2020

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Ben Berkhout

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19 January 2020

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Atze T Das

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19 January 2020

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Monique Vink

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19 January 2020

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Koen Verhoef

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19 January 2020

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Xue Zhou

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19 January 2020

Giuseppe Marzio

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19 January 2020

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20 April 2006

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19 January 2020

Journal of Biological Chemistry

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19 January 2020

281

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19 January 2020

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19 January 2020

17084-17091

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19 January 2020

Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells.

1 reference

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Simian immunodeficiency virus promoter exchange results in a highly attenuated strain that protects against uncloned challenge virus

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Live attenuated HIV vaccines: a proposal for further research and development.

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Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques

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Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques

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Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation

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Control over HIV-1 replication by an antibiotic; a novel vaccination strategy with a drug-dependent virus

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21 January 2018

A conditionally replicating virus as a novel approach toward an HIV vaccine

1 reference

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21 January 2018

Strict control of human immunodeficiency virus type 1 replication by a genetic switch: Tet for Tat.

1 reference

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21 January 2018

Constitutively dead, conditionally live HIV-1 genomes. Ex vivo implications for a live virus vaccine

1 reference

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21 January 2018

Conditional live virus as a novel approach towards a safe live attenuated HIV vaccine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513400200

21 January 2018

Tat trans-activates the human immunodeficiency virus through a nascent RNA target

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513400200

21 January 2018

Tat gets the "green" light on transcription initiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513400200

21 January 2018

Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513400200

21 January 2018

Transcriptional activation by tetracyclines in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513400200

21 January 2018

Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513400200

21 January 2018

Viral evolution as a tool to improve the tetracycline-regulated gene expression system

1 reference

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21 January 2018

Efficient human immunodeficiency virus replication requires a fine-tuned level of transcription

1 reference

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21 January 2018

In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies

1 reference

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21 January 2018

Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1

1 reference

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21 January 2018

Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513400200

21 January 2018

Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

1 reference

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21 January 2018

HIV-1 RNA editing, hypermutation, and error-prone reverse transcription

1 reference

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21 January 2018

G-->A hypermutation of the human immunodeficiency virus type 1 genome: evidence for dCTP pool imbalance during reverse transcription

1 reference

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21 January 2018

APOBEC3G versus reverse transcriptase in the generation of HIV-1 drug-resistance mutations

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21 January 2018

Nucleotide substitution patterns can predict the requirements for drug-resistance of HIV-1 proteins.

1 reference

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21 January 2018

The Tetracycline Repressor-A Paradigm for a Biological Switch

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21 January 2018

Conditional reduction of human immunodeficiency virus type 1 replication by a gain-of-herpes simplex virus 1 thymidine kinase function

1 reference

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21 January 2018

Rapid size dependent deletion of foreign gene sequences inserted into attenuated HIV-1 upon infection in vivo: implications for vaccine development

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21 January 2018

Construction of chimeric simian and human immunodeficiency viruses that produce interleukin 12.

1 reference

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21 January 2018

Potent and stable attenuation of live-HIV-1 by gain of a proteolysis-resistant inhibitor of NF-kappaB (IkappaB-alphaS32/36A) and the implications for vaccine development

1 reference

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21 January 2018

A novel autoregulated proliferation-controlled production process using recombinant CHO cells

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21 January 2018

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

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21 January 2018

Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance

1 reference

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21 January 2018

The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance

1 reference

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21 January 2018

Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system

1 reference

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21 January 2018

Stepwise selection of TetR variants recognizing tet operator 4C with high affinity and specificity

1 reference

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21 January 2018

Stepwise selection of TetR variants recognizing tet operator 6C with high affinity and specificity

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21 January 2018

Vaccination with live attenuated simian immunodeficiency virus for 21 days protects against superinfection

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Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor.

1 reference

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21 January 2018

Improving the safety of a conditional-live human immunodeficiency virus type 1 vaccine by controlling both gene expression and cell entry

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Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology

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21 January 2018

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10.1074/JBC.M513400200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16627480%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16627480%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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