(Q45606075)

14 December 2017

title

A conditionally replicating virus as a novel approach toward an HIV vaccine (English)

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14 December 2017

2

Koen Verhoef

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14 December 2017

3

Ben Berkhout

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14 December 2017

1

Atze T Das

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14 December 2017

language of work or name

English

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publication date

1 January 2004

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14 December 2017

published in

Methods in Enzymology

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14 December 2017

volume

388

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14 December 2017

page(s)

359-379

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Clinical trials of HIV vaccines.

14 December 2017

cites work

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New hope for an AIDS vaccine

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7 January 2021

Vaccines for the prevention of HIV-1 disease

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7 January 2021

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7 January 2021

Recent advances in the understanding of HIV accessory protein function

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7 January 2021

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

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7 January 2021

Multiple biological roles associated with the repeat (R) region of the HIV-1 RNA genome

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7 January 2021

Novel, live attenuated simian immunodeficiency virus constructs containing major deletions in leader RNA sequences

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7 January 2021

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

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7 January 2021

Construction and in vitro properties of SIVmac mutants with deletions in "nonessential" genes

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7 January 2021

Construction and in vitro properties of a series of attenuated simian immunodeficiency viruses with all accessory genes deleted

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7 January 2021

Live attenuated AIDS vaccines: hazards and hopes

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7 January 2021

Prospects for live attenuated HIV

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7 January 2021

Live attenuated HIV vaccines: a proposal for further research and development.

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7 January 2021

Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques

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7 January 2021

Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques

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7 January 2021

A truncated form of Nef selected during pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replication

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7 January 2021

Construction and in vitro properties of HIV-1 mutants with deletions in "nonessential" genes

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7 January 2021

A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Tat trans-activates the human immunodeficiency virus through a nascent RNA target

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7 January 2021

Activity of synthetic peptides from the Tat protein of human immunodeficiency virus type 1

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7 January 2021

Refolded HIV-1 tat protein protects both bulge and loop nucleotides in TAR RNA from ribonucleolytic cleavage

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

RNA recognition by Tat-derived peptides: interaction in the major groove?

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7 January 2021

Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Use of tetracycline-controlled gene expression systems to study mammalian cell cycle.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Mechanisms underlying expression of Tn10 encoded tetracycline resistance

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Transcriptional activation by tetracyclines in mammalian cells

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

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7 January 2021

Serum concentrations of penicillin, doxycycline, and ciprofloxacin during prolonged therapy in rhesus monkeys

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7 January 2021

Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI.

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7 January 2021

Structural features in TAR RNA of human and simian immunodeficiency viruses: a phylogenetic analysis

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7 January 2021

TAR RNA loop: a scaffold for the assembly of a regulatory switch in HIV replication

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7 January 2021

Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation

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7 January 2021

A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

1 reference

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7 January 2021

Interactions between Tat and TAR and human immunodeficiency virus replication are facilitated by human cyclin T1 but not cyclins T2a or T2b.

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7 January 2021

Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription

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7 January 2021

Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain

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7 January 2021

HIV-1 tat trans-activation requires the loop sequence within tar.

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7 January 2021

Requirements for DNA strand transfer during reverse transcription in mutant HIV-1 virions

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7 January 2021

Premature strand transfer by the HIV-1 reverse transcriptase during strong-stop DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Missense mutations in an infectious human immunodeficiency viral genome: functional mapping of tat and identification of the rev splice acceptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

High affinity binding of TAR RNA by the human immunodeficiency virus type-1 tat protein requires base-pairs in the RNA stem and amino acid residues flanking the basic region

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Determination of the minimal amount of Tat activity required for human immunodeficiency virus type 1 replication

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Functional substitution of the basic domain of the HIV-1 trans-activator, Tat, with the basic domain of the functionally heterologous Rev

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

On the role of the second coding exon of the HIV-1 Tat protein in virus replication and MHC class I downregulation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Tat is required for efficient HIV-1 reverse transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Human immunodeficiency viruses regulated by alternative trans-activators: genetic evidence for a novel non-transcriptional function of Tat in virion infectivity.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Human immunodeficiency virus type 1 protease regulation of tat activity is essential for efficient reverse transcription and replication

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Human immunodeficiency virus type 1 reverse transcription is stimulated by tat from other lentiviruses.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Identification of a sequence element immediately upstream of the polypurine tract that is essential for replication of simian immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

The scanning model for translation: an update

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies

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7 January 2021

Efficient human immunodeficiency virus replication requires a fine-tuned level of transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

A conserved hairpin motif in the R-U5 region of the human immunodeficiency virus type 1 RNA genome is essential for replication

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Conditional live virus as a novel approach towards a safe live attenuated HIV vaccine

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Strict control of human immunodeficiency virus type 1 replication by a genetic switch: Tet for Tat.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Vaccination with attenuated simian immunodeficiency virus by DNA inoculation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Viral evolution as a tool to improve the tetracycline-regulated gene expression system

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Control over HIV-1 replication by an antibiotic; a novel vaccination strategy with a drug-dependent virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Dox-dependent SIVmac with tetracycline-inducible promoter in the U3 promoter region

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Constitutively dead, conditionally live HIV-1 genomes. Ex vivo implications for a live virus vaccine

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Genetic instability of live, attenuated human immunodeficiency virus type 1 vaccine strains

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Structural requirements for trans activation of human immunodeficiency virus type 1 long terminal repeat-directed gene expression by tat: importance of base pairing, loop sequence, and bulges in the tat-responsive sequence.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Critical chemical features in trans-acting-responsive RNA are required for interaction with human immunodeficiency virus type 1 Tat protein

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Functional domains of Tat required for efficient human immunodeficiency virus type 1 reverse transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

A second-site mutation that restores replication of a Tat-defective human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

Upstream U3 sequences in simian immunodeficiency virus are selectively deleted in vivo in the absence of an intact nef gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2988028-5

7 January 2021

10.1016/S0076-6879(04)88028-5

Identifiers

DOI

1 reference

14 December 2017

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