(Q83207600)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16642023%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass (English)

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20 January 2020

14

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20 January 2020

12

Hitoshi Okamura

1 reference

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20 January 2020

author name string

Naoko Hashimoto

1

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20 January 2020

Yoshiaki Kido

2

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20 January 2020

Tohru Uchida

3

1 reference

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20 January 2020

Shun-ichiro Asahara

4

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20 January 2020

Yutaka Shigeyama

5

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20 January 2020

Tomokazu Matsuda

6

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20 January 2020

Akihiko Takeda

7

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20 January 2020

Daisuke Tsuchihashi

8

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20 January 2020

Akihiko Nishizawa

9

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20 January 2020

Wataru Ogawa

10

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20 January 2020

Yoshito Fujimoto

11

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20 January 2020

Karen C Arden

13

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20 January 2020

Tetsuo Noda

15

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20 January 2020

Masato Kasuga

16

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20 January 2020

publication date

23 April 2006

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20 January 2020

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20 January 2020

volume

38

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20 January 2020

issue

5

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20 January 2020

page(s)

589-593

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https://scigraph.springernature.com/pub.10.1038/ng1774

20 January 2020

exact match

0 references

cites work

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

7 January 2021

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

1 reference

7 January 2021

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

7 January 2021

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

1 reference

7 January 2021

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

7 January 2021

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

1 reference

7 January 2021

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice

1 reference

7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

7 January 2021

Essential role of PDK1 in regulating cell size and development in mice

1 reference

7 January 2021

FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

1 reference

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

7 January 2021

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

1 reference

7 January 2021

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth

1 reference

7 January 2021

Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice

1 reference

7 January 2021

Genetic control of cell size

1 reference

7 January 2021

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K.

1 reference

7 January 2021

Role for Akt3/protein kinase Bgamma in attainment of normal brain size

1 reference

7 January 2021

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

1 reference

7 January 2021

Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes

1 reference

7 January 2021

Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus

1 reference

7 January 2021

Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes

1 reference

7 January 2021

Role of hepatic STAT3 in brain-insulin action on hepatic glucose production

1 reference

7 January 2021

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

1 reference

7 January 2021

PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells

1 reference

7 January 2021

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

1 reference

7 January 2021

Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript.

1 reference

7 January 2021

Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG1774

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16642023%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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