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English
Emerging role of Mcl-1 in actively counteracting BH3-only proteins in apoptosis
scientific article published on 05 May 2006
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1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
title
Emerging role of Mcl-1 in actively counteracting BH3-only proteins in apoptosis
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
author
Hugh Brady
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
author name string
J Zhuang
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
publication date
5 May 2006
1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
volume
13
1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
page(s)
1263-1267
1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
issue
8
1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401952
0 references
cites work
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BH3-Only proteins-essential initiators of apoptotic cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
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7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of tumorigenesis by the p53 target PUMA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bad-deficient mice develop diffuse large B cell lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterisation of Mcl-1 cleavage during apoptosis of haematopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myeloid cell factor-1 is a critical survival factor for multiple myeloma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protective effect of phorbol esters on Fas-mediated apoptosis in T cells. Transcriptional and postranscriptional regulation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bisindolylmaleimide IX is a potent inducer of apoptosis in chronic lymphocytic leukaemic cells and activates cleavage of Mcl-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401952
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4401952
1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
PubMed ID
16676002
1 reference
stated in
Europe PubMed Central
PubMed ID
16676002
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16676002%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
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