(Q84113524)

English

The Ala allele in the PPAR-gamma2 gene is associated with reduced risk of type 2 diabetes mellitus in Caucasians and improved insulin sensitivity in overweight subjects

scientific article published on 27 April 2010

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20420754%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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The Ala allele in the PPAR-gamma2 gene is associated with reduced risk of type 2 diabetes mellitus in Caucasians and improved insulin sensitivity in overweight subjects (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20420754%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

type 2 diabetes

1 reference

based on heuristic

inferred from title

Grazielle Huguenin

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20420754%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Glorimar Rosa

2

1 reference

Europe PubMed Central

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1 February 2020

publication date

27 April 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20420754%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

British Journal of Nutrition

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20420754%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

104

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20420754%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20420754%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

488-497

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20420754%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral insulin sensitivity in a population with a high intake of oleic acid.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Measuring inconsistency in meta-analyses

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of two common polymorphisms of peroxisome proliferator-activated receptor-gamma gene on metabolic syndrome

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Impact of the Pro12Ala polymorphism of the PPAR-gamma2 gene on serum triacylglycerol response to n-3 fatty acid supplementation

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of genetic polymorphism peroxisome proliferator-activated receptor-gamma2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects: Evidence for heterogeneity.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

PPARgamma2 pro12Ala polymorphism and insulin resistance in Japanese hypertensive patients.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

The Effects of the Pro12Ala Polymorphism of the Peroxisome Proliferator-Activated Receptor- 2 Gene on Glucose/Insulin Metabolism Interact With Prenatal Exposure to Famine

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased insulin clearance in peroxisome proliferator-activated receptor gamma2 Pro12Ala

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

PPAR(gamma)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Impact of the Peroxisome Proliferator Activated Receptor γ2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasma lipids and diabetes risk in an Asian population

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 gene is associated with increased antilipolytic insulin sensitivity

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Variants in the PPARgamma gene affect fatty acid and glycerol metabolism in familial combined hyperlipidemia

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-diabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for gene-nutrient interaction at the PPARgamma locus.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Clustering of cardiovascular risk factors in hyperinsulinemia in Japanese without diabetes.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the Data From an Epidemiological Study on the Insulin Resi

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic variation in the peroxisome proliferator-activated receptor-gamma2 gene (Pro12Ala) affects metabolic responses to weight loss and subsequent weight regain

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant caucasians

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetics of the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of association between the Pro12Ala polymorphism in PPAR-gamma2 gene and body weight changes, insulin resistance and chronic diabetic complications in obese patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Ala12Ala genotype of the peroxisome proliferator-activated receptor gamma2 protects against atherosclerosis

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

High incidence of type 2 diabetes in peroxisome proliferator-activated receptor gamma2 Pro12Ala carriers exposed to a high chronic intake of trans fatty acids and saturated fatty acids

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

The common PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Hyperinsulinemia is an independent predictor for complex atherosclerotic lesion of thoracic aorta in non-diabetic patients

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Contribution of fasting hyperinsulinemia to prediction of atherosclerotic cardiovascular disease status in 293 hyperlipidemic patients.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Association between Pro12Ala polymorphism of the PPAR-gamma2 gene and insulin sensitivity in Brazilian patients with type-2 diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for genetic epistasis in human insulin resistance: the combined effect of PC-1 (K121Q) and PPARgamma2 (P12A) polymorphisms

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

The effect of the Ala12 allele of the peroxisome proliferator-activated receptor-gamma2 gene on skeletal muscle glucose uptake depends on obesity: a positron emission tomography study

1 reference

https://api.crossref.org/works/10.1017%2FS0007114510000851

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1017/S0007114510000851

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20420754%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20420754%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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