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Liver and serum iron: discrete regulators of hepatic hepcidin expression
scientific article published on 01 July 2011
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
editorial
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title
Liver and serum iron: discrete regulators of hepatic hepcidin expression
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
author
John K. Olynyk
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
author name string
Anita C G Chua
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Debbie Trinder
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
language of work or name
English
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publication date
1 July 2011
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
published in
Hepatology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
volume
54
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
page(s)
16-19
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
cites work
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diferric transferrin regulates transferrin receptor 2 protein stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered hepatic BMP signaling pathway in human HFE hemochromatosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FHEP.24449
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/HEP.24449
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
PubMed publication ID
21618572
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21618572
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618572%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
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