(Q84602874)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20665200%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Lipid A receptor TLR4-mediated signaling pathways (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20665200%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Lipid A Receptor TLR4-Mediated Signaling Pathways (English)

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

12 June 2024

author name string

Masahiro Yamamoto

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20665200%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Shizuo Akira

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20665200%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20665200

12 June 2024

publication date

1 January 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20665200%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

8 February 2020

http://link.springer.com/content/pdf/10.1007/978-1-4419-1603-7_6.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Advances in Experimental Medicine and Biology

12 June 2024

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20665200%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

667

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20665200%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

59-68

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20665200%20AND%20SRC:MED&resulttype=core&format=json

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

8 February 2020

cites work

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.282.5396.2085

Bacterial lipopolysaccharides: structure, metabolism and mechanisms of action

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Implication of Toll-like receptor and tumor necrosis factor alpha signaling in septic shock

12 June 2024

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CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

12 June 2024

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Nuclear factor kappa B, a mediator of lipopolysaccharide effects

12 June 2024

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

12 June 2024

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https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

12 June 2024

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TIR domain-containing adaptors define the specificity of TLR signaling

12 June 2024

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IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

12 June 2024

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

12 June 2024

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Unresponsiveness of MyD88-deficient mice to endotoxin

12 June 2024

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Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

12 June 2024

13

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IRF family of transcription factors as regulators of host defense

12 June 2024

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Essential role of IRF-3 in lipopolysaccharide-induced interferon-beta gene expression and endotoxin shock

12 June 2024

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

12 June 2024

16

1 reference

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Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

12 June 2024

17

1 reference

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

12 June 2024

18

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

12 June 2024

19

1 reference

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Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

12 June 2024

20

1 reference

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Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

12 June 2024

21

1 reference

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RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

12 June 2024

22

1 reference

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Cutting Edge: NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation

12 June 2024

23

1 reference

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Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways

12 June 2024

24

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

12 June 2024

25

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

12 June 2024

26

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

TIRAP: an adapter molecule in the Toll signaling pathway

12 June 2024

27

1 reference

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

12 June 2024

28

1 reference

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

12 June 2024

29

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

12 June 2024

30

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

12 June 2024

31

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

12 June 2024

32

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.

12 June 2024

33

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Pathogen recognition and innate immunity

12 June 2024

34

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction

12 June 2024

35

1 reference

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12 June 2024

36

1 reference

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Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

12 June 2024

37

1 reference

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Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease

12 June 2024

38

1 reference

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Negative regulation of toll-like receptor-mediated immune responses

12 June 2024

39

1 reference

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Cutting edge: naturally occurring soluble form of mouse Toll-like receptor 4 inhibits lipopolysaccharide signaling

12 June 2024

40

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors

12 June 2024

41

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

12 June 2024

42

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

SOCS-1 participates in negative regulation of LPS responses

12 June 2024

43

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

SOCS1/JAB is a negative regulator of LPS-induced macrophage activation

12 June 2024

44

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88

12 June 2024

45

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Negative regulation of Toll-like-receptor signaling by IRF-4.

12 June 2024

46

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

12 June 2024

47

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

IRAK-M is a negative regulator of Toll-like receptor signaling

12 June 2024

48

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory

12 June 2024

49

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

12 June 2024

50

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

The role of TRAF6 in signal transduction and the immune response

12 June 2024

51

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Essential function for the kinase TAK1 in innate and adaptive immune responses.

12 June 2024

52

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

12 June 2024

53

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

12 June 2024

54

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

12 June 2024

55

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

A20 is a negative regulator of IFN regulatory factor 3 signaling.

12 June 2024

56

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

PI3K-mediated negative feedback regulation of IL-12 production in DCs

12 June 2024

57

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

PI3K and negative regulation of TLR signaling.

12 June 2024

58

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Regulation of lipopolysaccharide-inducible genes by MyD88 and Toll/IL-1 domain containing adaptor inducing IFN-β

12 June 2024

59

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Toll IL-1 receptors differ in their ability to promote the stabilization of adenosine and uridine-rich elements containing mRNA

12 June 2024

60

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Stimulus-specific induction of a novel nuclear factor-kappaB regulator, IkappaB-zeta, via Toll/Interleukin-1 receptor is mediated by mRNA stabilization

12 June 2024

61

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

A novel IkappaB protein, IkappaB-zeta, induced by proinflammatory stimuli, negatively regulates nuclear factor-kappaB in the nuclei

12 June 2024

62

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production

12 June 2024

63

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Isolation of a novel interleukin-1-inducible nuclear protein bearing ankyrin-repeat motifs

12 June 2024

64

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta

12 June 2024

65

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

The nuclear IkappaB protein IkappaBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria

12 June 2024

66

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

IkappaBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation.

12 June 2024

67

1 reference

https://api.crossref.org/works/10.1007/978-1-4419-1603-7_6

12 June 2024

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20665200%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference