(Q85341798)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Triterpenoids as novel natural inhibitors of human cathepsin L (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

Schinus terebinthifolius

1 reference

[(Z,6S)-6-[(5R,9R,10R,13S,14R,17S)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]hept-2-en-2-yl] acetate

1 reference

methyl (2Z,6S)-6-[(1S,3aS,5aR,7E,9aR,9bR,11aS)-7-(hydroxyimino)-3a,6,6,9a,11a-pentamethyl-1H,2H,3H,5H,5aH,8H,9H,9bH,10H,11H-cyclopenta[a]phenanthren-1-yl]-2-methylhept-2-enoate

1 reference

(2Z,6S)-6-[(1S,3aS,5aR,7E,9aR,9bR,11aS)-7-(hydroxyimino)-3a,6,6,9a,11a-pentamethyl-1H,2H,3H,5H,5aH,8H,9H,9bH,10H,11H-cyclopenta[a]phenanthren-1-yl]-2-methylhept-2-enoic acid

1 reference

1 reference

Oleanolic acid 3-acetate

1 reference

[(Z,6S)-6-[(5R,9R,10R,13S,14R,17S)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-2-en-2-yl] formate

1 reference

methyl (1S,2R,4aS,6aR,6aS,6bR,8aR,12aR,14bS)-10-acetyloxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate

1 reference

[(Z,6S)-6-[(5R,9R,10R,13S,14R,17S)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]hept-2-en-2-yl] formate

1 reference

(1S,2R,4aS,6aR,6aS,6bR,8aR,12aR,14bS)-10-acetyloxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid

1 reference

3-(Hydroxyimino)oleana-12-ene-28-oic acid

1 reference

3-Oxo-olean-12-en-28-oic acid

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Paulo Cezar Vieira

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

5

Ignez Caracelli

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

4

Stella H Maganhi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Suelem D Ramalho

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Lorena R F De Sousa

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Julio Zukerman-Schpector

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Maria Inês S Lima

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Marcio F M Alves

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

M Fátima das G F Da Silva

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

João B Fernandes

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

publication date

1 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

Chemistry and Biodiversity

16 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

1354-1363

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

Antitumoractive endoperoxides from triterpenes

16 February 2020

cites work

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Triterpenoids from Dysoxylum pettigrewianum

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Natural products as a source of potential cancer chemotherapeutic and chemopreventive agents

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Anticancer effect of A-ring or/and C-ring modified oleanolic acid derivatives on KB, MCF-7 and HeLa cell lines

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Acridone alkaloids as potent inhibitors of cathepsin V.

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Cathepsin L increases invasion and migration of B16 melanoma

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Antibacterial triterpenes from Syzygium guineense (Myrtaceae).

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Two Novel Triterpenes from the Leaves ofFicus microcarpa

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Natural products for cancer prevention: a global perspective

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

The cathepsin family and their role in colorectal cancer

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Development of cathepsin inhibitors and structure-based design of cathepsin B-specific inhibitor

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Clinically useful anticancer, antitumor, and antiwrinkle agent, ursolic acid and related derivatives as medicinally important natural product

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Triterpenoids isolated from Machaerium incorruptibile

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Systematic investigation of halogen bonding in protein-ligand interactions

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Development and validation of a genetic algorithm for flexible docking

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Dirhamnosyl flavonoid and other constituents from Brillantaisia palisatii

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Dual contrasting roles of cysteine cathepsins in cancer progression: apoptosis versus tumour invasion.

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Expression of human cathepsin K in Pichia pastoris and preliminary crystallographic studies of an inhibitor complex

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Highly selective azadipeptide nitrile inhibitors for cathepsin K: design, synthesis and activity assays

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Cysteine proteases as disease markers

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Impact of natural products on developing new anti-cancer agents

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Human liver cathepsin L

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Halogen bonding at the active sites of human cathepsin L and MEK1 kinase: efficient interactions in different environments

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Anti-inflammatory activity of lupeol and lupeol linoleate in rats

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Tirucallane-type triterpenes from Juliania adstringens

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Pentacyclic triterpenoids from the medicinal herb, Centella asiatica (L.) Urban.

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

On the size of the active site in proteases. I. Papain

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibition

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Natural triterpenoids from Cecropia lyratiloba are cytotoxic to both sensitive and multidrug resistant leukemia cell lines

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/CBDV.201400065

Identifiers

DOI

10.1002/CBDV.201400065

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25238076%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference