(Q41265835)

28 September 2017

Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype (English)

1 reference

28 September 2017

1 reference

Donna M Huryn

7

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author name string

Michael C Myers

1

1 reference

28 September 2017

Parag P Shah

2

1 reference

28 September 2017

Mary Pat Beavers

3

1 reference

28 September 2017

Andrew D Napper

4

1 reference

28 September 2017

Scott L Diamond

5

1 reference

28 September 2017

Amos B Smith

6

1 reference

28 September 2017

language of work or name

English

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publication date

1 May 2008

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28 September 2017

6

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Bioorganic & Medicinal Chemistry Letters

inferred from page(s)

published in

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28 September 2017

18

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28 September 2017

12

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28 September 2017

3646-3651

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Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Identification and synthesis of a unique thiocarbazate cathepsin L inhibitor

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Identification and characterization of 3-substituted pyrazolyl esters as alternate substrates for cathepsin B: the confounding effects of DTT and cysteine in biological assays

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Emerging roles of cysteine cathepsins in disease and their potential as drug targets.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Novel semicarbazide-derived inhibitors of human dipeptidyl peptidase I (hDPPI).

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Non-peptidic inhibitors of cysteine proteases.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Recent advances in the synthesis, design and selection of cysteine protease inhibitors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Secreted cathepsin L generates endostatin from collagen XVIII

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Pyrrolidine-3-carboxylic acids as endothelin antagonists. 4. Side chain conformational restriction leads to ET(B) selectivity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

The lysosomal cysteine proteases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Inhibition of bone resorption by selective inactivators of cysteine proteinases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Purification of cathepsin B by a new form of affinity chromatography

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Azapeptides as inhibitors and active site titrants for cysteine proteinases.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Cysteine protease inhibition by azapeptide esters

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Aza-amino acid scanning of secondary structure suited for solid-phase peptide synthesis with fmoc chemistry and aza-amino acids with heteroatomic side chains

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Azepanone-based inhibitors of human cathepsin L.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Targeting cathepsin L (CL) by specific ribozymes decreases CL protein synthesis and cartilage destruction in rheumatoid arthritis.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

Identification of Leishmania major cysteine proteinases as targets of the immune response in humans

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494853

From good substrates to good inhibitors: design of inhibitors for serine and thiol proteases

19 August 2018

1 reference

12 December 2020

Azadepsipeptides: synthesis and evaluation of a novel class of peptidomimetics

1 reference

12 December 2020

Cysteine proteinase inhibitors decrease articular cartilage and bone destruction in chronic inflammatory arthritis

1 reference

12 December 2020

Cysteine Proteases and Their Inhibitors

1 reference

12 December 2020

10.1016/J.BMCL.2008.04.065

Identifiers

DOI

1 reference

28 September 2017

1 reference

28 September 2017

1 reference