(Q87075238)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Activation of a promyelocytic leukemia-tumor protein 53 axis underlies acute promyelocytic leukemia cure (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

acute promyelocytic leukemia

4 March 2020

main subject

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

Kim Rice

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Hassane Soilihi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Aurélien de Reynies

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Saverio Minucci

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Hugues de Thé

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

publication date

12 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

167-174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412926%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nm.3441

4 March 2020

exact match

0 references

cites work

How acute promyelocytic leukaemia revived arsenic

1 reference

12 December 2020

Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient

1 reference

12 December 2020

Deconstructing PML-induced premature senescence

1 reference

12 December 2020

Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet

1 reference

12 December 2020

Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterations

1 reference

12 December 2020

Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia

1 reference

12 December 2020

p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal

1 reference

12 December 2020

Pro-senescence therapy for cancer treatment

1 reference

12 December 2020

Uncoupling RARA transcriptional activation and degradation clarifies the bases for APL response to therapies

1 reference

12 December 2020

PML is induced by oncogenic ras and promotes premature senescence

1 reference

12 December 2020

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

1 reference

12 December 2020

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

1 reference

12 December 2020

Reconstructing a disease: What essential features of the retinoic acid receptor fusion oncoproteins generate acute promyelocytic leukemia?

1 reference

12 December 2020

Acute promyelocytic leukaemia: novel insights into the mechanisms of cure

1 reference

12 December 2020

Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL).

1 reference

12 December 2020

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

1 reference

12 December 2020

Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia

1 reference

12 December 2020

Molecular signature of retinoic acid treatment in acute promyelocytic leukemia

1 reference

12 December 2020

The origin and evolution of mutations in acute myeloid leukemia

1 reference

12 December 2020

Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence

1 reference

12 December 2020

Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins

1 reference

12 December 2020

Curing APL: differentiation or destruction?

1 reference

12 December 2020

PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3.

1 reference

12 December 2020

PML targeting eradicates quiescent leukaemia-initiating cells

1 reference

12 December 2020

Characterization of endogenous human promyelocytic leukemia isoforms

1 reference

12 December 2020

Phase II study of single-agent arsenic trioxide for the front-line therapy of acute promyelocytic leukemia.

1 reference

12 December 2020

Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins

1 reference

12 December 2020

Lamin B1 loss is a senescence-associated biomarker.

1 reference

12 December 2020

Lysosome-mediated processing of chromatin in senescence.

1 reference

12 December 2020

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

1 reference

12 December 2020

E2F target genes: unraveling the biology

1 reference

12 December 2020

Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia

1 reference

12 December 2020

1 reference

12 December 2020

All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia

1 reference

12 December 2020

Transcriptome analysis reveals that p53 and {beta}-catenin alterations occur in a group of aggressive adrenocortical cancers.

1 reference

12 December 2020

Human papillomavirus oncoprotein E7 targets the promyelocytic leukemia protein and circumvents cellular senescence via the Rb and p53 tumor suppressor pathways

1 reference

12 December 2020

Impairment of p53 acetylation, stability and function by an oncogenic transcription factor

1 reference

12 December 2020

The coagulopathy of acute promyelocytic leukaemia revisited

1 reference

12 December 2020

RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia

1 reference

12 December 2020

Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia

1 reference

12 December 2020

Two critical hits for promyelocytic leukemia

1 reference

12 December 2020

Use of all-trans retinoic acid plus arsenic trioxide as an alternative to chemotherapy in untreated acute promyelocytic leukemia

1 reference

12 December 2020

Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia

1 reference

12 December 2020

Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML.

1 reference

12 December 2020

The role of the bone marrow in neutrophil clearance under homeostatic conditions in the mouse

1 reference

12 December 2020

PML-RAR induces promyelocytic leukemias with high efficiency following retroviral gene transfer into purified murine hematopoietic progenitors

1 reference

12 December 2020

Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RARalpha) and oncogenic RARalpha fusion proteins

1 reference

12 December 2020

Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: long-term follow-up data

1 reference

12 December 2020

Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway

1 reference

12 December 2020

PML regulates p53 stability by sequestering Mdm2 to the nucleolus

1 reference

12 December 2020

The function of PML in p53-dependent apoptosis

1 reference

12 December 2020

Arsenic-induced PML targeting onto nuclear bodies: implications for the treatment of acute promyelocytic leukemia

1 reference

12 December 2020

Single-agent liposomal all-trans retinoic acid can cure some patients with untreated acute promyelocytic leukemia: an update of The University of Texas M. D. Anderson Cancer Center Series.

1 reference

12 December 2020

Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia

1 reference

12 December 2020

Effective targeting of chronic myeloid leukemia initiating activity with the combination of arsenic trioxide and interferon alpha

1 reference

12 December 2020

Non-cell-autonomous tumor suppression by p53.

1 reference

12 December 2020

Regulation of E2Fs and senescence by PML nuclear bodies.

1 reference

12 December 2020

Transcriptional induction of the PML growth suppressor gene by interferons is mediated through an ISRE and a GAS element.

1 reference

12 December 2020

Retinoic acid and arsenic trioxide for acute promyelocytic leukemia

1 reference

12 December 2020