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Kinetic template-guided tethering of fragments
scientific article published on 02 October 2012
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
title
Kinetic template-guided tethering of fragments
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
author name string
Rebecca H Nonoo
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Alan Armstrong
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
David J Mann
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
publication date
2 October 2012
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
published in
ChemMedChem
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
volume
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
issue
12
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
page(s)
2082-2086
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
cites work
Experiences in fragment-based drug discovery
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
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Drugging challenging targets using fragment-based approaches
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Crossref
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https://api.crossref.org/works/10.1002%2FCMDC.201200404
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7 January 2021
based on heuristic
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Fragment-Based Drug Discovery
1 reference
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Crossref
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https://api.crossref.org/works/10.1002%2FCMDC.201200404
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7 January 2021
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Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery
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7 January 2021
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Recent progress in fragment-based lead discovery
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Crossref
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https://api.crossref.org/works/10.1002%2FCMDC.201200404
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7 January 2021
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Fragment-based drug design: how big is too big?
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Crossref
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7 January 2021
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The rise of fragment-based drug discovery
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7 January 2021
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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
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7 January 2021
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Tethering: fragment-based drug discovery
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2FCMDC.201200404
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tethering identifies fragment that yields potent inhibitors of human caspase-1
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7 January 2021
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Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug design
1 reference
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Crossref
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https://api.crossref.org/works/10.1002%2FCMDC.201200404
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7 January 2021
based on heuristic
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In situ assembly of enzyme inhibitors using extended tethering
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https://api.crossref.org/works/10.1002%2FCMDC.201200404
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7 January 2021
based on heuristic
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Discovery of an Aurora kinase inhibitor through site-specific dynamic combinatorial chemistry
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https://api.crossref.org/works/10.1002%2FCMDC.201200404
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7 January 2021
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Discovery of a potent small molecule IL-2 inhibitor through fragment assembly
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https://api.crossref.org/works/10.1002%2FCMDC.201200404
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7 January 2021
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Covalent capture: merging covalent and noncovalent synthesis
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7 January 2021
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Evaluation of vinylsulfamides as sulfhydryl selective alkylation reagents in protein modification
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7 January 2021
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A mechanism-based aryl carrier protein/thiolation domain affinity probe
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Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones
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Relative rates of Michael reactions of 2'-(phenethyl)thiol with vinyl sulfones, vinyl sulfonate esters, and vinyl sulfonamides relevant to vinyl sulfonyl cysteine protease inhibitors
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Targeted covalent drugs of the kinase family
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The resurgence of covalent drugs
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7 January 2021
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Covalent modifiers: an orthogonal approach to drug design
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Antibodies with infinite affinity
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Selective inhibition of engineered receptors via proximity-accelerated alkylation
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The catalytic mechanism and structure of thymidylate synthase
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Crystal-structure-based design and synthesis of benz[cd]indole-containing inhibitors of thymidylate synthase
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Kinetic scheme for thymidylate synthase from Escherichia coli: determination from measurements of ligand binding, primary and secondary isotope effects, and pre-steady-state catalysis.
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Secondary metabolites from the root wood of Zanthoxylum wutaiense and their antitubercular activity
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COCI
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Identifiers
DOI
10.1002/CMDC.201200404
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PubMed publication ID
23033251
1 reference
stated in
Europe PubMed Central
PubMed publication ID
23033251
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23033251%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
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