(Q34722632)

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Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones (English)

1 reference

Europe PubMed Central

4 August 2017

Plasmodium falciparum

0 references

Philip J Rosenthal

8

object named as

Philip J Rosenthal

1 reference

Europe PubMed Central

4 August 2017

author name string

Bhaskar R Shenai

1

1 reference

Europe PubMed Central

4 August 2017

Belinda J Lee

2

1 reference

Europe PubMed Central

4 August 2017

Alejandro Alvarez-Hernandez

3

1 reference

Europe PubMed Central

4 August 2017

Pek Y Chong

4

1 reference

Europe PubMed Central

4 August 2017

Cory D Emal

5

1 reference

Europe PubMed Central

4 August 2017

R Jeffrey Neitz

6

1 reference

Europe PubMed Central

4 August 2017

William R Roush

7

1 reference

Europe PubMed Central

4 August 2017

language of work or name

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publication date

1 January 2003

1 reference

Europe PubMed Central

4 August 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

4 August 2017

47

1 reference

Europe PubMed Central

4 August 2017

1

1 reference

Europe PubMed Central

4 August 2017

154-160

1 reference

Europe PubMed Central

4 August 2017

Cysteine proteases of parasitic organisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149004

7 July 2018

Hydrolysis of erythrocyte proteins by proteases of malaria parasites

1 reference

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7 July 2018

Medical need, scientific opportunity and the drive for antimalarial drugs

1 reference

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The economic and social burden of malaria

1 reference

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7 July 2018

Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine

1 reference

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7 July 2018

Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3

1 reference

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Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense

1 reference

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Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain

1 reference

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Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

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Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum

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Synthesis and biological activity of a series of potent fluoromethyl ketone inhibitors of recombinant human calpain I.

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7 July 2018

Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

1 reference

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An orally bioavailable pyrrolinone inhibitor of HIV-1 protease: computational analysis and X-ray crystal structure of the enzyme complex

1 reference

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7 July 2018

Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149004

7 July 2018

Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors

1 reference

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7 July 2018

Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria

1 reference

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7 July 2018

The proteases and pathogenicity of parasitic protozoa

1 reference

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Vinylogous amino acid esters: a new class of inactivators for thiol proteases

1 reference

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7 July 2018

A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum

1 reference

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7 July 2018

Isolation and characterization of a cysteine proteinase gene of Plasmodium falciparum

1 reference

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Discovery of a peptide-based renin inhibitor with oral bioavailability and efficacy

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Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture

1 reference

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7 July 2018

Reducing requirements for hemoglobin hydrolysis by Plasmodium falciparum cysteine proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149004

26 October 2018

Antimalarial effects in mice of orally administered peptidyl cysteine protease inhibitors

1 reference

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26 October 2018

Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors

1 reference

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Peptidyl vinyl sulphones: a new class of potent and selective cysteine protease inhibitors: S2P2 specificity of human cathepsin O2 in comparison with cathepsins S and L.

1 reference

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Vinyl sulfones as mechanism-based cysteine protease inhibitors

1 reference

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Determination of the rate constant of enzyme modification by measuring the substrate reaction in the presence of the modifier.

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Orally active trifluoromethyl ketone inhibitors of human leukocyte elastase

1 reference

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Discovery of a novel, selective, and orally bioavailable class of thrombin inhibitors incorporating aminopyridyl moieties at the P1 position

1 reference

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Structure-activity relationships for inhibition of papain by peptide Michael acceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12499184

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inferred from PubMed ID database lookup

Discovery and biological activity of orally active peptidyl trifluoromethyl ketone inhibitors of human neutrophil elastase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12499184

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inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.47.1.154-160.2003

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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