(Q88435826)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29682330%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

title

Yes-associated protein (YAP) in pancreatic cancer: at the epicenter of a targetable signaling network associated with patient survival (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29682330%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29682330%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

author name string

Enrique Rozengurt

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29682330%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

James Sinnett-Smith

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29682330%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

publication date

20 April 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29682330%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29682330%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

page(s)

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29682330%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

24 March 2020

copyright license

start time

20 April 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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7 January 2021

Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States

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7 January 2021

Genetics and biology of pancreatic ductal adenocarcinoma

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7 January 2021

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

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7 January 2021

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

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7 January 2021

RAS oncogenes: weaving a tumorigenic web

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7 January 2021

KRAS: feeding pancreatic cancer proliferation

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https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

1 reference

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7 January 2021

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Mechanisms of Hippo pathway regulation

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Control of YAP/TAZ Activity by Metabolic and Nutrient-Sensing Pathways.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

YAP/TAZ at the Roots of Cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The emerging roles of YAP and TAZ in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Identification of Happyhour/MAP4K as Alternative Hpo/Mst-like Kinases in the Hippo Kinase Cascade

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Aerobic glycolysis tunes YAP/TAZ transcriptional activity

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

TAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell-like Behaviors Contributing to Disease Progression

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The Hippo pathway: regulators and regulations

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD).

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Protein kinase D signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Protein kinase D signaling: multiple biological functions in health and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

YAP enhances the pro-proliferative transcriptional activity of mutant p53 proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Hippo transducer TAZ promotes epithelial mesenchymal transition and supports pancreatic cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

KRAS and YAP1 converge to regulate EMT and tumor survival

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Overexpression of Yes Associated Protein 1, an Independent Prognostic Marker in Patients With Pancreatic Ductal Adenocarcinoma, Correlated With Liver Metastasis and Poor Prognosis.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

A pathology atlas of the human cancer transcriptome

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

YAP is essential for tissue tension to ensure vertebrate 3D body shape

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

YAP Regulates Actin Dynamics through ARHGAP29 and Promotes Metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

YAP/TEAD-mediated transcription controls cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Alternative Wnt Signaling Activates YAP/TAZ.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Hippo signaling mediates proliferation, invasiveness, and metastatic potential of clear cell renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Ezrin protein overexpression predicts the poor prognosis of pancreatic ductal adenocarcinomas

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Structural analysis of the cancer-specific promoter in mesothelin and in other genes overexpressed in cancers.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Regulation of actin-binding protein ANLN by antitumor miR-217 inhibits cancer cell aggressiveness in pancreatic ductal adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Expression of amphiregulin predicts poor outcome in patients with pancreatic ductal adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Cyclin D1 is a strong prognostic factor for survival in pancreatic cancer: analysis of CD G870A polymorphism, FISH and immunohistochemistry.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Serum dickkopf-1 is a novel serological biomarker for the diagnosis and prognosis of pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Prognostic Value of FOXM1 in Patients with Malignant Solid Tumor: A Meta-Analysis and System Review

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

A novel survival-based tissue microarray of pancreatic cancer validates MUC1 and mesothelin as biomarkers.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Receptor for Hyaluronic Acid-Mediated Motility is Associated with Poor Survival in Pancreatic Ductal Adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Ribonucleotide reductase subunit M2 mRNA expression in pretreatment biopsies obtained from unresectable pancreatic carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

SERP1 is a novel marker of poor prognosis in pancreatic ductal adenocarcinoma patients via anti-apoptosis and regulating SRPRB/NF-κB axis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Oncoprotein YAP regulates the spindle checkpoint activation in a mitotic phosphorylation-dependent manner through up-regulation of BubR1.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

AJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Silencing IGFBP-2 decreases pancreatic cancer metastasis and enhances chemotherapeutic sensitivity

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Bile acids activate YAP to promote liver carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Ezrin regulates skin fibroblast size/mechanical properties and YAP-dependent proliferation

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

MUC1-C Represses the Crumbs Complex Polarity Factor CRB3 and Downregulates the Hippo Pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

PKCι regulates nuclear YAP1 localization and ovarian cancer tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

P2Y2 Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Overexpression of G protein-coupled receptor GPR87 promotes pancreatic cancer aggressiveness and activates NF-κB signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs).

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Role of YAP/TAZ in mechanotransduction

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

AHNAK interaction with the annexin 2/S100A10 complex regulates cell membrane cytoarchitecture

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The Role of Cholesterol in Cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

LKB1; linking cell structure and tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Dysregulation of the mevalonate pathway promotes transformation

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Structural mechanism for statin inhibition of HMG-CoA reductase

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The association of statin use after cancer diagnosis with survival in pancreatic cancer patients: a SEER-medicare analysis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Impact of statin use on survival in patients undergoing resection for early-stage pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Statins and the risk of pancreatic cancer in Type 2 diabetic patients--A population-based cohort study

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Statin use and risk of pancreatic cancer: results from a large, clinic-based case-control study

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The differential effects of statins on the risk of developing pancreatic cancer: a case-control study in two centres in the United Kingdom

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Statin Use and Its Impact on Survival in Pancreatic Cancer Patients

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Metabolic control of YAP and TAZ by the mevalonate pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The blooming of the French lilac

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Metformin and cancer risk and mortality: a systematic review and meta-analysis taking into account biases and confounders

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The effect of metformin on survival of patients with pancreatic cancer: a meta-analysis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Metformin inhibits the growth of human pancreatic cancer xenografts

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Metformin suppresses cancer initiation and progression in genetic mouse models of pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

AMPK modulates Hippo pathway activity to regulate energy homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The gamma secretase inhibitor MRK-003 attenuates pancreatic cancer growth in preclinical models

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

A phase II study of the gamma secretase inhibitor RO4929097 in patients with previously treated metastatic pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

A Multicenter, Open-Label Phase II Clinical Trial of Combined MEK plus EGFR Inhibition for Chemotherapy-Refractory Advanced Pancreatic Adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Small molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancers

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

YAP activation is an early event and a potential therapeutic target in liver cancer development.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Verteporfin inhibits growth of human glioma in vitro without light activation

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Verteporfin-induced formation of protein cross-linked oligomers and high molecular weight complexes is mediated by light and leads to cell toxicity

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Structural insights into the YAP and TEAD complex

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches.

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Metformin Improves Survival in Patients with Pancreatic Ductal Adenocarcinoma and Pre-Existing Diabetes: A Propensity Score Analysis

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Effects of statins on cancer mortality and progression: A systematic review and meta-analysis of 95 cohorts including 1,111,407 individuals

1 reference

https://api.crossref.org/works/10.1038%2FS41392-017-0005-2

7 January 2021

Modulation of Syrian hamster 3-hydroxy-3-methylglutaryl-CoA reductase activity by phosphorylation. Role of serine 871.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29682330

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41392-017-0005-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29682330%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29682330%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

PubMed publication ID

29682330

1 reference