(Q88537168)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29716959%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

title

The phospholipase A2 activity of peroxiredoxin 6 (English)

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25 March 2020

author name string

Aron B Fisher

series ordinal

1

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25 March 2020

publication date

1 May 2018

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Journal of Lipid Research

25 March 2020

published in

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25 March 2020

volume

59

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25 March 2020

issue

7

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25 March 2020

page(s)

1132-1147

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A competitive inhibitor of phospholipase A2 decreases surfactant phosphatidylcholine degradation by the rat lung

25 March 2020

cites work

1 reference

12 December 2020

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

1 reference

12 December 2020

Active-site-directed specific competitive inhibitors of phospholipase A2: novel transition-state analogues

1 reference

12 December 2020

A serine protease triad forms the catalytic centre of a triacylglycerol lipase

1 reference

12 December 2020

Degradation of pulmonary surfactant disaturated phosphatidylcholines by alveolar macrophages

1 reference

12 December 2020

Lung lamellar bodies maintain an acidic internal pH

1 reference

12 December 2020

Intracellular processing of surfactant lipids in the lung

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12 December 2020

Identification of neutral active phospholipase C which hydrolyzes choline glycerophospholipids and plasmalogen selective phospholipase A2 in canine myocardium

1 reference

12 December 2020

Identification of phospholipase A 1 and A 2 in the soluble fraction of rat liver lysosomes

1 reference

12 December 2020

Unsaturated fatty acids as second messengers of superoxide generation by macrophages

1 reference

12 December 2020

1 reference

12 December 2020

Marked increase of human platelet phospholipase A2 activity in vitro and demonstration of an endogenous inhibitor

1 reference

12 December 2020

Distinct inhibition of membrane-bound and lysosomal phospholipase A2 by glucocorticoid-induced proteins

1 reference

12 December 2020

The influence of phospholipase A2 and glutathione peroxidase on the elimination of membrane lipid peroxides

1 reference

12 December 2020

Mammalian calcium-independent phospholipase A2.

1 reference

12 December 2020

Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad

1 reference

12 December 2020

Kinetic basis for interfacial catalysis by phospholipase A2.

1 reference

12 December 2020

Inhibition of lung calcium-independent phospholipase A2 by surfactant protein A

1 reference

12 December 2020

Inhibition of Trimeresurus flavoviridis phospholipase A2 by lung surfactant protein A (SP-A)

1 reference

12 December 2020

Ca(2+)-independent cytosolic phospholipase A2 from macrophage-like P388D1 cells. Isolation and characterization

1 reference

12 December 2020

Role of phospholipase A2 enzymes in degradation of dipalmitoylphosphatidylcholine by granular pneumocytes

1 reference

12 December 2020

Identification of a human cDNA clone for lysosomal type Ca2+-independent phospholipase A2 and properties of the expressed protein

1 reference

12 December 2020

Role of acidic Ca2+-independent phospholipase A2 in synthesis of lung dipalmitoyl phosphatidylcholine

1 reference

12 December 2020

Essential requirement of cytosolic phospholipase A2 for activation of the phagocyte NADPH oxidase.

1 reference

12 December 2020

Characterization of a mammalian peroxiredoxin that contains one conserved cysteine

1 reference

12 December 2020

Purification and characterization of 1-O-acylceramide synthase, a novel phospholipase A2 with transacylase activity.

1 reference

12 December 2020

Crystal structure of a novel human peroxidase enzyme at 2.0 A resolution

1 reference

12 December 2020

Cloning and expression of rat lung acidic Ca(2+)-independent PLA2 and its organ distribution.

1 reference

12 December 2020

Lipid hydroperoxide generation, turnover, and effector action in biological systems

1 reference

12 December 2020

Characterization of acidic Ca(2+)-independent phospholipase A2 of bovine lung

1 reference

12 December 2020

A novel phosphatidylglycerol-selective phospholipase A2 from macrophages

1 reference

12 December 2020

Moonlighting proteins.

1 reference

12 December 2020

Phospholipid hydroperoxides are substrates for non-selenium glutathione peroxidase

1 reference

12 December 2020

1-Cys peroxiredoxin, a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities

1 reference

12 December 2020

The expanding superfamily of phospholipase A(2) enzymes: classification and characterization

1 reference

12 December 2020

Surfactant protein A (SP-A): the alveolus and beyond

1 reference

12 December 2020

Lysosomal-type PLA2 and turnover of alveolar DPPC

1 reference

12 December 2020

Interfacial enzymology: the secreted phospholipase A(2)-paradigm.

1 reference

12 December 2020

Peroxiredoxin, a novel family of peroxidases

1 reference

12 December 2020

Overexpression of peroxiredoxins I, II, III, V, and VI in malignant mesothelioma

1 reference

12 December 2020

A 29-kDa protein associated with p67phox expresses both peroxiredoxin and phospholipase A2 activity and enhances superoxide anion production by a cell-free system of NADPH oxidase activity

1 reference

12 December 2020

Involvement of calcium-independent phospholipase A2 in hydrogen peroxide-induced accumulation of free fatty acids in human U937 cells

1 reference

12 December 2020

Expression patterns of antioxidant proteins in brains of patients with sporadic Creutzfeldt-Jacob disease

1 reference

12 December 2020

Nonselenium glutathione peroxidase in human brain : elevated levels in Parkinson's disease and dementia with lewy bodies

1 reference

12 December 2020

Phospholipase A2 enzymes

1 reference

12 December 2020

Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders

1 reference

12 December 2020

Mice with targeted mutation of peroxiredoxin 6 develop normally but are susceptible to oxidative stress

1 reference

12 December 2020

Susceptibility to oxidative stress: proteomic analysis of bronchoalveolar lavage from ozone‐sensitive and ozone‐resistant strains of mice

1 reference

12 December 2020

L-PhGPx expression can be suppressed by antisense oligodeoxynucleotides

1 reference

12 December 2020

1-Cys peroxiredoxin knock-out mice express mRNA but not protein for a highly related intronless gene

1 reference

12 December 2020

Cloning of bovine peroxiredoxins-gene expression in bovine tissues and amino acid sequence comparison with rat, mouse and primate peroxiredoxins

1 reference

12 December 2020

Lysosomal phospholipase A2 is selectively expressed in alveolar macrophages

1 reference

12 December 2020

Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase

1 reference

12 December 2020

Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Altered lung phospholipid metabolism in mice with targeted deletion of lysosomal-type phospholipase A2.

1 reference

12 December 2020

Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism

1 reference

12 December 2020

Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling

1 reference

12 December 2020

Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues

1 reference

12 December 2020

Interaction of surfactant protein A with peroxiredoxin 6 regulates phospholipase A2 activity

1 reference

12 December 2020

Enhanced expression of peroxiredoxin I and VI correlates with development, recurrence and progression of human bladder cancer.

1 reference

12 December 2020

Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1.

1 reference

12 December 2020

Lung phospholipid metabolism in transgenic mice overexpressing peroxiredoxin 6

1 reference

12 December 2020

Positive role of reactive oxygen species in mammalian sperm capacitation: triggering and modulation of phosphorylation events

1 reference

12 December 2020

The phospholipase A2 superfamily and its group numbering system

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12 December 2020

Structure and phospholipase function of peroxiredoxin 6: identification of the catalytic triad and its role in phospholipid substrate binding.

1 reference

12 December 2020

Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer

1 reference

12 December 2020

Peroxiredoxins in the lung with emphasis on peroxiredoxin VI.

1 reference

12 December 2020

TAT-mediated PRDX6 protein transduction protects against eye lens epithelial cell death and delays lens opacity

1 reference

12 December 2020

Peroxiredoxin 6 in human brain: molecular forms, cellular distribution and association with Alzheimer's disease pathology

1 reference

12 December 2020

Cytochrome c: functions beyond respiration

1 reference

12 December 2020

H2O2-dependent hyperoxidation of peroxiredoxin 6 (Prdx6) plays a role in cellular toxicity via up-regulation of iPLA2 activity

1 reference

12 December 2020

Recent progress on acyl CoA: lysophospholipid acyltransferase research

1 reference

12 December 2020

Phospholipase A2 structure/function, mechanism, and signaling

1 reference

12 December 2020

Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice

1 reference

12 December 2020

Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity

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12 December 2020

Binding of peroxiredoxin 6 to substrate determines differential phospholipid hydroperoxide peroxidase and phospholipase A(2) activities

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12 December 2020

TAT-mediated peroxiredoxin 5 and 6 protein transduction protects against high-glucose-induced cytotoxicity in retinal pericytes

1 reference

12 December 2020

Moonlighting proteins--an update.

1 reference

12 December 2020

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12 December 2020

Phospholipase A2 subclasses in acute respiratory distress syndrome

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12 December 2020

Identification of the amino acid sequence that targets peroxiredoxin 6 to lysosome-like structures of lung epithelial cells

1 reference

12 December 2020

1-Cysteine peroxiredoxin: A dual-function enzyme with peroxidase and acidic Ca2+-independent phospholipase A2 activities

1 reference

12 December 2020

Phospholipase A2 activity of peroxiredoxin 6 promotes invasion and metastasis of lung cancer cells

1 reference

12 December 2020

Pathway to lamellar bodies for surfactant protein A.

1 reference

12 December 2020

The measurement of lysosomal phospholipase A2 activity in plasma

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12 December 2020

Increased expression of peroxiredoxin 6 and cyclophilin A in squamous cell carcinoma of the tongue

1 reference

12 December 2020

Group XV phospholipase A₂, a lysosomal phospholipase A₂.

1 reference

12 December 2020

Comparative proteomic analysis of differentially expressed proteins in primary retinoblastoma tumors.

1 reference

12 December 2020

Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages

1 reference

12 December 2020

Intracellular targeting of peroxiredoxin 6 to lysosomal organelles requires MAPK activity and binding to 14-3-3ε

1 reference

12 December 2020

Phospholipase A(2) of peroxiredoxin 6 has a critical role in tumor necrosis factor-induced apoptosis

1 reference

12 December 2020

Proteins with neomorphic moonlighting functions in disease.

1 reference

12 December 2020

Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention

1 reference

12 December 2020

The roles of peroxidase and phospholipase A2 activities of peroxiredoxin 6 in protecting pulmonary microvascular endothelial cells against peroxidative stress

1 reference

12 December 2020

Stop the flow: a paradigm for cell signaling mediated by reactive oxygen species in the pulmonary endothelium

1 reference

12 December 2020

Peroxiredoxin 6 translocates to the plasma membrane during neutrophil activation and is required for optimal NADPH oxidase activity

1 reference

12 December 2020

Low amounts and high thiol oxidation of peroxiredoxins in spermatozoa from infertile men

1 reference

12 December 2020

Molecular cloning reveals nearly half of patients with Crohn's disease have an antibody to peroxiredoxin 6-like protein

1 reference

12 December 2020

Increased phospholipase A2 activity with phosphorylation of peroxiredoxin 6 requires a conformational change in the protein

1 reference

12 December 2020

The acute respiratory distress syndrome

1 reference

12 December 2020

p67(phox) terminates the phospholipase A(2)-derived signal for activation of NADPH oxidase (NOX2)

1 reference

12 December 2020

A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lung

1 reference

12 December 2020

Polymorphisms in oxidative stress-related genes and mortality in breast cancer patients – Potential differential effects by radiotherapy?

1 reference

12 December 2020

Dual role of the antioxidant enzyme peroxiredoxin 6 in skin carcinogenesis

1 reference

12 December 2020

Lung tumor growth-promoting function of peroxiredoxin 6.

1 reference

12 December 2020

Dipalmitoyl-phosphatidylcholine biosynthesis is induced by non-injurious mechanical stretch in a model of alveolar type II cells

1 reference

12 December 2020

Acceleration of the development of Alzheimer's disease in amyloid beta-infused peroxiredoxin 6 overexpression transgenic mice.

1 reference

12 December 2020

Exploratory proteomic analysis of hypobaric hypoxia and acute mountain sickness in humans.

1 reference

12 December 2020

Protein and miRNA profiling of radiation-induced skin injury in rats: the protective role of peroxiredoxin-6 against ionizing radiation

1 reference

12 December 2020

Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2).

1 reference

12 December 2020

PRDX6 promotes lung tumor progression via its GPx and iPLA2 activities

1 reference

12 December 2020

Conformational flexibility in the catalytic triad revealed by the high-resolution crystal structure ofStreptomyces erythraeustrypsin in an unliganded state

1 reference

12 December 2020

Biochemical characterization of a phospholipase A2 from Photobacterium damselae subsp. piscicida

1 reference

12 December 2020

Peroxiredoxin VI oxidation in cerebrospinal fluid correlates with traumatic brain injury outcome

1 reference

12 December 2020

Cellular mechanisms and physiological consequences of redox-dependent signalling

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12 December 2020

Loss of presenilin 2 is associated with increased iPLA2 activity and lung tumor development

1 reference

12 December 2020

Peroxiredoxin 6, a novel player in the pathogenesis of diabetes

1 reference

12 December 2020

PRDX6 Exacerbates Dopaminergic Neurodegeneration in a MPTP Mouse Model of Parkinson's Disease

1 reference

12 December 2020

A primer on peroxiredoxin biochemistry

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12 December 2020

PRDX6 promotes tumor development via the JAK2/STAT3 pathway in a urethane-induced lung tumor model.

1 reference

12 December 2020

Membranes serve as allosteric activators of phospholipase A2, enabling it to extract, bind, and hydrolyze phospholipid substrates

1 reference

12 December 2020

Inhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia

1 reference

12 December 2020

Solution structure of the reduced form of human peroxiredoxin-6 elucidated using zero-length chemical cross-linking and homology modelling

1 reference

12 December 2020

Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice.

1 reference

12 December 2020

A new era of secreted phospholipase A₂

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12 December 2020

Cytosolic phospholipase A₂: physiological function and role in disease

1 reference

12 December 2020

High intensity of cytoplasmic peroxiredoxin VI expression is associated with adverse outcome in diffuse large B-cell lymphoma independently of International Prognostic Index.

1 reference

12 December 2020

Autoimmune Profiling Reveals Peroxiredoxin 6 as a Candidate Traumatic Brain Injury Biomarker

1 reference

12 December 2020

Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling

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12 December 2020

Critical role of peroxiredoxin 6 in the repair of peroxidized cell membranes following oxidative stress

1 reference

12 December 2020

Phospholipase A2 Isoforms as Novel Targets for Prevention and Treatment of Inflammatory and Oncologic Diseases

1 reference

12 December 2020

Antioxidant peroxiredoxin 6 protein rescues toxicity due to oxidative stress and cellular hypoxia in vitro, and attenuates prion-related pathology in vivo

1 reference

12 December 2020

Peroxiredoxin 6 triggers melanoma cell growth by increasing arachidonic acid-dependent lipid signalling

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12 December 2020

The phospholipase A2 activity of peroxiredoxin 6 promotes cancer cell death induced by tumor necrosis factor alpha in hepatocellular carcinoma

1 reference

12 December 2020

PRDX6 controls multiple sclerosis by suppressing inflammation and blood brain barrier disruption

1 reference

12 December 2020

Peroxiredoxin 6 from the Antarctic emerald rockcod: molecular characterization of its response to warming

1 reference

12 December 2020

Protein species and moonlighting proteins: Very small changes in a protein's covalent structure can change its biochemical function.

1 reference

12 December 2020

Loss of Peroxiredoxin Expression Is Associated with an Aggressive Phenotype in Pancreatic Adenocarcinoma

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12 December 2020

Binding sites for interaction of peroxiredoxin 6 with surfactant protein A.

1 reference

12 December 2020

Absence of Peroxiredoxin 6 Amplifies the Effect of Oxidant Stress on Mobility and SCSA/CMA3 Defined Chromatin Quality and Impairs Fertilizing Ability of Mouse Spermatozoa.

1 reference

12 December 2020

A novel lysophosphatidylcholine acyl transferase activity is expressed by peroxiredoxin 6

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12 December 2020

Overview on Peroxiredoxin

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12 December 2020

Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activity

1 reference

12 December 2020

Mutation of Serine 32 to Threonine in Peroxiredoxin 6 Preserves Its Structure and Enzymatic Function but Abolishes Its Trafficking to Lamellar Bodies

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12 December 2020

Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration

1 reference

12 December 2020

The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation via lysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages.

1 reference

12 December 2020

Crystal structures of human peroxiredoxin 6 in different oxidation states

1 reference

12 December 2020

The role of Prdx6 in the protection of cells of the crystalline lens from oxidative stress induced by UV exposure

1 reference

12 December 2020

Expression of Peroxiredoxins and Pulmonary Surfactant Protein A Induced by Silica in Rat Lung Tissue.

1 reference

12 December 2020

miR-24-3p Regulates Progression of Gastric Mucosal Lesions and Suppresses Proliferation and Invasiveness of N87 Via Peroxiredoxin 6.

1 reference

12 December 2020

Pulmonary surfactant metabolism in the alveolar airspace: Biogenesis, extracellular conversions, recycling

1 reference

12 December 2020

Peroxiredoxin 6 in the repair of peroxidized cell membranes and cell signaling

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12 December 2020

Quantitative HDL Proteomics Identifies Peroxiredoxin-6 as a Biomarker of Human Abdominal Aortic Aneurysm.

1 reference

12 December 2020

The Antioxidant Peroxiredoxin 6 (Prdx6) Exhibits Different Profiles in the Livers of Seawater- and Fresh Water-Acclimated Milkfish, Chanos chanos, upon Hypothermal Challenge

1 reference

12 December 2020

Preferential hydrolysis of truncated oxidized glycerophospholipids by lysosomal phospholipase A2.

1 reference

12 December 2020

Peroxiredoxins prevent oxidative stress during human sperm capacitation

1 reference

12 December 2020

Analyses of Calcium-Independent Phospholipase A2beta (iPLA2β) in Biological Systems

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12 December 2020

The role of peroxiredoxins in cancer.

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12 December 2020

Peroxiredoxin 6 phospholipid hydroperoxidase activity in the repair of peroxidized cell membranes

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12 December 2020

Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase.

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12 December 2020

Deficiency of peroxiredoxin 6 or inhibition of its phospholipase A2 activity impair the in vitro sperm fertilizing competence in mice

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12 December 2020

Active-site plasticity revealed in the asymmetric dimer of AnPrx6 the 1-Cys peroxiredoxin and molecular chaperone from Anabaena sp. PCC 7210.

1 reference

12 December 2020

Review of four major distinct types of human phospholipase A2.

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.R082578

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29716959%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

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25 March 2020

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