(Q38214052)

31 August 2017

Cellular mechanisms and physiological consequences of redox-dependent signalling (English)

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31 August 2017

1

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31 August 2017

Toren Finkel

2

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31 August 2017

language of work or name

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1 June 2014

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Nature Reviews Molecular Cell Biology

31 August 2017

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31 August 2017

15

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31 August 2017

6

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31 August 2017

411-421

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https://scigraph.springernature.com/pub.10.1038/nrm3801

31 August 2017

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Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity.

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Regulation of protein tyrosine phosphatase oxidation in cell adhesion and migration

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Redox regulation of PI 3-kinase signalling via inactivation of PTEN

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Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors

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Redox regulation of Cdc25C.

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Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression

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Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling

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Regulation of ROS signal transduction by NADPH oxidase 4 localization

21 January 2018

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A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation

21 January 2018

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SelR reverses Mical-mediated oxidation of actin to regulate F-actin dynamics

21 January 2018

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MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation

21 January 2018

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Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path

21 January 2018

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Redox-dependent control of FOXO/DAF-16 by transportin-1.

21 January 2018

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Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution

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Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

21 January 2018

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A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.

21 January 2018

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21 January 2018

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Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species

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Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox-mediated generation of reactive oxygen species

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Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination.

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TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

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Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

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Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling

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A role for mitochondria in NLRP3 inflammasome activation

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Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

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ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages

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Redox regulation of stem/progenitor cells and bone marrow niche

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Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

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FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

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Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

21 January 2018

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Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 January 2018

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Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

21 January 2018

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The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity

21 January 2018

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Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress

21 January 2018

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Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity

21 January 2018

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Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner

21 January 2018

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Nox2 redox signaling maintains essential cell populations in the brain

21 January 2018

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ROS are required for mouse spermatogonial stem cell self-renewal

21 January 2018

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Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

21 January 2018

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The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled

21 January 2018

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A crucial role for Nox 1 in redox-dependent regulation of Wnt-β-catenin signaling.

21 January 2018

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Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development

21 January 2018

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Forkhead box o as a sensor, mediator, and regulator of redox signaling.

21 January 2018

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NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon

21 January 2018

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Epigenetic silencing mediates mitochondria stress-induced longevity

21 January 2018

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Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells.

21 January 2018

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Deubiquitinases as a signaling target of oxidative stress

21 January 2018

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Regulation of A20 and other OTU deubiquitinases by reversible oxidation

21 January 2018

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The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

21 January 2018

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Oxidants, antioxidants and the current incurability of metastatic cancers

21 January 2018

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

21 January 2018

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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

21 January 2018

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Autophagy, stress, and cancer metabolism: what doesn't kill you makes you stronger

21 January 2018

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Modulation of intracellular ROS levels by TIGAR controls autophagy

21 January 2018

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Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

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Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress

21 January 2018

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ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

21 January 2018

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Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

21 January 2018

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Reactive oxygen species are downstream mediators of p53-dependent apoptosis

21 January 2018

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A model for p53-induced apoptosis

21 January 2018

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p53, ROS and senescence in the control of aging

21 January 2018

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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

21 January 2018

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Modulation of oxidative stress as an anticancer strategy

21 January 2018

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Mitochondria, oxidants, and aging

21 January 2018

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Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

21 January 2018

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A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans

21 January 2018

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Extension of murine life span by overexpression of catalase targeted to mitochondria

21 January 2018

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Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

21 January 2018

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Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal

21 January 2018

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Early mitochondrial dysfunction in long-lived Mclk1+/- mice

21 January 2018

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Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

21 January 2018

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A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes

21 January 2018

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Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2

21 January 2018

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Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling

21 January 2018

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Antioxidants prevent health-promoting effects of physical exercise in humans

21 January 2018

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Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix

21 January 2018

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Methods for detection of mitochondrial and cellular reactive oxygen species

21 January 2018

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Boronate-based fluorescent probes for imaging cellular hydrogen peroxide

21 January 2018

1 reference

Molecular imaging of hydrogen peroxide produced for cell signaling

21 January 2018

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Measuring E(GSH) and H2O2 with roGFP2-based redox probes.

21 January 2018

1 reference

Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxides

21 January 2018

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SOD1 integrates signals from oxygen and glucose to repress respiration

21 January 2018

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SIRT3 regulation of mitochondrial oxidative stress

21 January 2018

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Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling

21 January 2018

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Folding and stability of the Z and S(iiyama) genetic variants of human alpha1-antitrypsin

21 January 2018

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Antimycin-insensitive oxidation of succinate and reduced nicotinamide-adenine dinucleotide in electron-transport particles. I. pH dependency and hydrogen peroxide formation

31 March 2020

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Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes

31 March 2020

1 reference

Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation

31 March 2020

1 reference

Peroxiredoxins are conserved markers of circadian rhythms

31 March 2020

1 reference

The physiological role of reversible methionine oxidation

31 March 2020

1 reference

Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance

31 March 2020

1 reference

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

31 March 2020

1 reference

Genetically encoded fluorescent indicator for intracellular hydrogen peroxide

31 March 2020

1 reference

Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing.

31 March 2020

1 reference

12 December 2020

Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation

1 reference

12 December 2020

Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity

1 reference

12 December 2020

Mutation of the Cyba gene encoding p22phox causes vestibular and immune defects in mice

1 reference

12 December 2020

Physiological levels of reactive oxygen species are required to maintain genomic stability in stem cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRM3801

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Dimensions Publication ID

31 August 2017

1010887648

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Fatcat ID

release_z6xesqyegjepbhhgahbmgqxive

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Fatcat

https://api.fatcat.wiki/v0/release/z6xesqyegjepbhhgahbmgqxive

24 November 2022

mapped directly with Wikidata item

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