(Q89568615)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

title

NAD+ Depletion Triggers Macrophage Necroptosis, a Cell Death Pathway Exploited by Mycobacterium tuberculosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

1 reference

Mycobacterium tuberculosis

1 reference

1 reference

David Pajuelo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Norberto Gonzalez-Juarbe

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Uday Tak

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

Michael Niederweis

series ordinal

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

publication date

1 July 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

volume

24

1 reference

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6 April 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

page(s)

429-440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

6 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6136256/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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12 December 2020

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

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Cytochrome c release from mitochondria proceeds by a two-step process

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12 December 2020

Critical role of mitochondrial damage in determining outcome of macrophage infection with Mycobacterium tuberculosis

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THP-1 cell apoptosis in response to Mycobacterial infection

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12 December 2020

FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis

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Protection elicited by a double leucine and pantothenate auxotroph of Mycobacterium tuberculosis in guinea pigs.

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Enhancement of antimycobacterial activity of macrophages by stabilization of inner mitochondrial membrane potential

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Necrotic death as a cell fate

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A mechanism of virulence: virulent Mycobacterium tuberculosis strain H37Rv, but not attenuated H37Ra, causes significant mitochondrial inner membrane disruption in macrophages leading to necrosis.

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12 December 2020

Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway

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12 December 2020

NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences

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12 December 2020

4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.

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12 December 2020

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

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12 December 2020

Mycobacterial nucleoside diphosphate kinase blocks phagosome maturation in murine RAW 264.7 macrophages

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12 December 2020

Adjusting transgene expression levels in lymphocytes with a set of inducible promoters

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Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?

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12 December 2020

Induction of cell death after localization to the host cell mitochondria by the Mycobacterium tuberculosis PE_PGRS33 protein

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Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis

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12 December 2020

Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase-1- and cathepsin B-independent necrosis

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12 December 2020

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification

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12 December 2020

Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis

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12 December 2020

Targeting of Mycobacterium tuberculosis heparin-binding hemagglutinin to mitochondria in macrophages

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12 December 2020

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

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12 December 2020

Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death

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12 December 2020

Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages

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12 December 2020

The dynamic regulation of NAD metabolism in mitochondria

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12 December 2020

Role of TNF-Alpha, IFN-Gamma, and IL-10 in the Development of Pulmonary Tuberculosis

1 reference

12 December 2020

Bioinformatic identification of Mycobacterium tuberculosis proteins likely to target host cell mitochondria: virulence factors?

1 reference

12 December 2020

Characterizing virulence-specific perturbations in the mitochondrial function of macrophages infected with Mycobacterium tuberculosis

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12 December 2020

Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo.

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12 December 2020

TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species

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12 December 2020

Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

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12 December 2020

SIRT1 and other sirtuins in metabolism

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12 December 2020

Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

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12 December 2020

The protein import machinery of mitochondria-a regulatory hub in metabolism, stress, and disease

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12 December 2020

Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.

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12 December 2020

Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.

1 reference

12 December 2020

An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity

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12 December 2020

ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion.

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12 December 2020

Cell death and autophagy in tuberculosis

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12 December 2020

Necroptosis: Pathway diversity and characteristics

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12 December 2020

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12 December 2020

The Streptococcus pyogenes NAD(+) glycohydrolase modulates epithelial cell PARylation and HMGB1 release

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12 December 2020

Mycobacterium tuberculosis effectors interfering host apoptosis signaling.

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12 December 2020

A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.

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12 December 2020

The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD

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12 December 2020

Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia

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12 December 2020

NAD⁺ in aging, metabolism, and neurodegeneration.

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12 December 2020

Necroptosis and Inflammation

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12 December 2020

Perspectives on mycobacterial vacuole-to-cytosol translocation: the importance of cytosolic access

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12 December 2020

Comparative evaluation of in vitro human macrophage models for mycobacterial infection study

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12 December 2020

Biosensor reveals multiple sources for mitochondrial NAD⁺.

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12 December 2020

An evolutionary perspective on the necroptotic pathway

1 reference

12 December 2020

Roles of Caspases in Necrotic Cell Death.

1 reference

12 December 2020

Necroptosis in development, inflammation and disease.

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12 December 2020

Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis

1 reference

12 December 2020

Mycobacterium tuberculosis replicates within necrotic human macrophages

1 reference

12 December 2020

Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia

1 reference

12 December 2020

Bcl-xL mediates RIPK3-dependent necrosis in M. tuberculosis-infected macrophages

1 reference

12 December 2020

Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis

1 reference

12 December 2020

Susceptibility of M. tuberculosis-infected host cells to phospho-MLKL driven necroptosis is dependent on cell type and presence of TNFα.

1 reference

12 December 2020

Host-directed therapies for bacterial and viral infections.

1 reference

12 December 2020

Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted.

1 reference

12 December 2020

Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule.

1 reference

12 December 2020

NAD+ deficiency is a common central pathological factor of a number of diseases and aging: Mechanisms and therapeutic implications

1 reference

12 December 2020

10.1016/J.CELREP.2018.06.042

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29996103%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

PubMed publication ID

29996103

1 reference