(Q89842982)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32087851%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

title

Bioflavonoids cause DNA double-strand breaks and chromosomal translocations through topoisomerase II-dependent and -independent mechanisms (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32087851%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

5

Christine Richardson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32087851%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

author name string

Donna Goodenow

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32087851%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

Faith Emmanuel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32087851%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

Chase Berman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32087851%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

Mark Sahyouni

4

1 reference

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9 April 2020

publication date

22 January 2020

1 reference

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9 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32087851%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

volume

849

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32087851%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

page(s)

503144

1 reference

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HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

9 April 2020

cites work

1 reference

12 December 2020

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

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Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP16-213 and VM26: a quantitative structure-activity relationship

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12 December 2020

Sequence analysis of the breakpoint cluster region in the ALL-1 gene involved in acute leukemia.

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12 December 2020

Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites

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12 December 2020

Analysis of foetal expression sites of human type II DNA topoisomerase alpha and beta mRNAs by in situ hybridisation.

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12 December 2020

Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots

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12 December 2020

Bis(2,6-dioxopiperazines), catalytic inhibitors of DNA topoisomerase II, as molecular probes, cardioprotectors and antitumor drugs

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12 December 2020

Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia

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12 December 2020

Dietary intake and bioavailability of polyphenols

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12 December 2020

Dietary flavonoids: bioavailability, metabolic effects, and safety

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12 December 2020

Quercetin suppresses proinflammatory cytokines production through MAP kinases andNF-kappaB pathway in lipopolysaccharide-stimulated macrophage

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12 December 2020

Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187

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12 December 2020

Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties

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12 December 2020

Flavonoids in food and their health benefits

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12 December 2020

Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis: a report from the children's oncology group

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12 December 2020

Cleavage of the MLL gene by activators of apoptosis is independent of topoisomerase II activity

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12 December 2020

Fetal exposure to phytoestrogens--the difference in phytoestrogen status between mother and fetus

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12 December 2020

Topoisomerase II and the etiology of chromosomal translocations

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12 December 2020

Intakes and sources of soya foods and isoflavones in a UK population cohort study (EPIC-Norfolk).

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12 December 2020

Bioflavonoids as poisons of human topoisomerase II alpha and II beta

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12 December 2020

Dietary flavonoids induce MLL translocations in primary human CD34+ cells

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12 December 2020

Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.

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12 December 2020

Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane

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12 December 2020

Dietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancement

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12 December 2020

The dietary bioflavonoid, quercetin, selectively induces apoptosis of prostate cancer cells by down-regulating the expression of heat shock protein 90.

1 reference

12 December 2020

The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

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12 December 2020

New insights to the MLL recombinome of acute leukemias

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12 December 2020

Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements

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12 December 2020

Genistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemia

1 reference

12 December 2020

An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway

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12 December 2020

Myricetin induces pancreatic cancer cell death via the induction of apoptosis and inhibition of the phosphatidylinositol 3-kinase (PI3K) signaling pathway

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12 December 2020

The pathogenesis of mixed-lineage leukemia

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12 December 2020

Maternal quercetin intake during pregnancy results in an adapted iron homeostasis at adulthood

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12 December 2020

Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state

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12 December 2020

Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity

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12 December 2020

TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo

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12 December 2020

Topoisomerase II and leukemia

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12 December 2020

Long-term effects of chromatin remodeling and DNA damage in stem cells induced by environmental and dietary agents

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12 December 2020

Cancer chemoprevention by traditional chinese herbal medicine and dietary phytochemicals: targeting nrf2-mediated oxidative stress/anti-inflammatory responses, epigenetics, and cancer stem cells.

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12 December 2020

Etoposide quinone is a covalent poison of human topoisomerase IIβ.

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12 December 2020

Oxidative stress, bone marrow failure, and genome instability in hematopoietic stem cells

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12 December 2020

Leukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanism

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12 December 2020

Dietary polyphenols and chromatin remodeling

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12 December 2020

New functionally-enhanced soy proteins as food ingredients with anti-viral activity

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12 December 2020

Roles of eukaryotic topoisomerases in transcription, replication and genomic stability

1 reference

12 December 2020

Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes.

1 reference

12 December 2020

Bioflavonoids promote stable translocations between MLL-AF9 breakpoint cluster regions independent of normal chromosomal context: Model system to screen environmental risks

1 reference

12 December 2020

Measurement and Clinical Significance of Lipid Peroxidation as a Biomarker of Oxidative Stress: Oxidative Stress in Diabetes, Atherosclerosis, and Chronic Inflammation

1 reference

12 December 2020

Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity

1 reference

12 December 2020