(Q90262599)

English

Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells

scientific article published on 24 September 2019

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

7

object named as

Satoshi Endo

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Toshiyuki Matsunaga

6

object named as

Toshiyuki Matsunaga

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

author name string

Ryohei Maruhashi

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Hiroaki Eguchi

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Risa Akizuki

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Shohei Hamada

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Takumi Furuta

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Kenji Ichihara

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

publication date

24 September 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Scientific Reports

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

13753

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6760125/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Comprehensive genomic characterization of squamous cell lung cancers

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Nivolumab Versus Docetaxel in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer: Two-Year Outcomes From Two Randomized, Open-Label, Phase III Trials (CheckMate 017 and CheckMate 057).

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Anti-PD-1/PD-L1 Therapy for Non-Small-Cell Lung Cancer: Toward Personalized Medicine and Combination Strategies

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Implication of tumor microenvironment in chemoresistance: tumor-associated stromal cells protect tumor cells from cell death

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanisms of drug resistance and its reversal in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

The Role of Tumor Microenvironment in Chemoresistance: To Survive, Keep Your Enemies Closer.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Elevation of sensitivity to anticancer agents of human lung adenocarcinoma A549 cells by knockdown of claudin-2 expression in monolayer and spheroid culture models

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Decrease in paracellular permeability and chemosensitivity to doxorubicin by claudin-1 in spheroid culture models of human lung adenocarcinoma A549 cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

AMP-activated protein kinase (AMPK) activation is involved in chrysin-induced growth inhibition and apoptosis in cultured A549 lung cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptotic effects of chrysin in human cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Chrysin activates Notch1 signaling and suppresses tumor growth of anaplastic thyroid carcinoma in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Chrysin: a histone deacetylase 8 inhibitor with anticancer activity and a suitable candidate for the standardization of Chinese propolis

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Chrysin inhibits expression of hypoxia-inducible factor-1 through reducing hypoxia-inducible factor-1 stability and inhibiting its protein synthesis

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Chrysin Increases the Therapeutic Efficacy of Docetaxel and Mitigates Docetaxel-Induced Edema.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Claudin-5, -7, and -18 suppress proliferation mediated by inhibition of phosphorylation of Akt in human lung squamous cell carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular basis of the core structure of tight junctions

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

ABC transporters as cancer drivers: Potential functions in cancer development

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Tight junction-based epithelial microenvironment and cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Barrier function of epithelia

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Signalling to and from tight junctions

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Recent discoveries of anticancer flavonoids

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of claudin interactions in airway tight junctional permeability

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental regulation of claudin localization by fetal alveolar epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of claudin-1 in the beta-catenin/Tcf signaling pathway and its frequent upregulation in human colorectal cancers

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Claudin expression in gastric adenocarcinomas: a tissue microarray study with prognostic correlation.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Discovery of novel tumor markers of pancreatic cancer using global gene expression technology

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Claudin-1 and claudin-5 expression patterns differentiate lung squamous cell carcinomas from adenocarcinomas

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased expression of claudin-3 is associated with a poor prognosis and EMT in completely resected squamous cell lung carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced expression of claudin-7 is associated with poor outcome in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Non-small cell lung cancers frequently express phosphorylated Akt; an immunohistochemical study.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Estrogen/GPR30 Signaling Contributes to the Malignant Potentials of ER-Negative Cervical Adenocarcinoma via Regulation of Claudin-1 Expression

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Nm23H1 mediates tumor invasion in esophageal squamous cell carcinoma by regulation of CLDN1 through the AKT signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Chemopreventive and therapeutic potential of chrysin in cancer: mechanistic perspectives.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Chrysin inhibits metastatic potential of human triple-negative breast cancer cells by modulating matrix metalloproteinase-10, epithelial to mesenchymal transition, and PI3K/Akt signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Chrysin-induced apoptosis is mediated through caspase activation and Akt inactivation in U937 leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Chemoresistance and the Self-Maintaining Tumor Microenvironment

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Design, synthesis and biological evaluation of chrysin long-chain derivatives as potential anticancer agents

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and single enzyme activity of a clicked lipase–BSA hetero-dimer

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-50276-Z

7 January 2021

based on heuristic

inferred from DOI database lookup

The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31551535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-small-cell lung cancer: molecular targeted therapy and personalized medicine - drug resistance, mechanisms, and strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/31551535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin (PI3K-Akt-mTOR) signaling pathway in non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/31551535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/S41598-019-50276-Z

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31551535%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q90262599&oldid=1986015043"