(Q90622386)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563911%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

title

Human papillomavirus and the landscape of secondary genetic alterations in oral cancers (English)

1 reference

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lip and oral cavity carcinoma

15 April 2020

main subject

1 reference

1

Maura L Gillison

1 reference

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15 April 2020

author name string

Keiko Akagi

2

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15 April 2020

Weihong Xiao

3

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15 April 2020

Bo Jiang

4

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15 April 2020

Robert K L Pickard

5

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15 April 2020

Jingfeng Li

6

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15 April 2020

Benjamin J Swanson

7

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15 April 2020

Amit D Agrawal

8

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15 April 2020

Mark Zucker

9

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15 April 2020

Birgit Stache-Crain

10

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15 April 2020

Anne-Katrin Emde

11

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15 April 2020

Heather M Geiger

12

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15 April 2020

Nicolas Robine

13

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15 April 2020

Kevin R Coombes

14

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15 April 2020

David E Symer

15

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15 April 2020

publication date

18 December 2018

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15 April 2020

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15 April 2020

volume

29

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15 April 2020

issue

1

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15 April 2020

page(s)

1-17

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Genetic progression model for head and neck cancer: implications for field cancerization

15 April 2020

cites work

1 reference

12 December 2020

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

1 reference

12 December 2020

The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300.

1 reference

12 December 2020

Evidence for a causal association between human papillomavirus and a subset of head and neck cancers

1 reference

12 December 2020

Identification of the familial cylindromatosis tumour-suppressor gene

1 reference

12 December 2020

Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes

1 reference

12 December 2020

RIP4 is an ankyrin repeat-containing kinase essential for keratinocyte differentiation

1 reference

12 December 2020

Cellular signaling by fibroblast growth factor receptors

1 reference

12 December 2020

Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus

1 reference

12 December 2020

Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma.

1 reference

12 December 2020

Human papillomavirus type 16 E6 activates NF-kappaB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner

1 reference

12 December 2020

Papillomavirus genome structure, expression, and post-transcriptional regulation

1 reference

12 December 2020

Human papillomavirus E6 proteins mediate resistance to interferon-induced growth arrest through inhibition of p53 acetylation

1 reference

12 December 2020

Nuclear ubiquitin ligases, NF-kappaB degradation, and the control of inflammation

1 reference

12 December 2020

Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers

1 reference

12 December 2020

Activation of Akt as a mechanism for tumor immune evasion

1 reference

12 December 2020

CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes

1 reference

12 December 2020

The Sequence Alignment/Map format and SAMtools

1 reference

12 December 2020

Fast and accurate long-read alignment with Burrows-Wheeler transform

1 reference

12 December 2020

p300 alters keratinocyte cell growth and differentiation through regulation of p21(Waf1/CIP1).

1 reference

12 December 2020

Fast and SNP-tolerant detection of complex variants and splicing in short reads

1 reference

12 December 2020

Human papillomavirus and survival of patients with oropharyngeal cancer.

1 reference

12 December 2020

The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis

1 reference

12 December 2020

NFX1 plays a role in human papillomavirus type 16 E6 activation of NFkappaB activity

1 reference

12 December 2020

NF-κB as a target for oncogenic viruses

1 reference

12 December 2020

Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming

1 reference

12 December 2020

CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression

1 reference

12 December 2020

Assessment of human papillomavirus in lung tumor tissue

1 reference

12 December 2020

PIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitro

1 reference

12 December 2020

The mutational landscape of head and neck squamous cell carcinoma

1 reference

12 December 2020

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

1 reference

12 December 2020

Regulation of antiviral innate immunity by deubiquitinase CYLD.

1 reference

12 December 2020

Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States

1 reference

12 December 2020

Pocket proteins suppress head and neck cancer

1 reference

12 December 2020

Loss of gene function as a consequence of human papillomavirus DNA integration.

1 reference

12 December 2020

Characterization of critical domains within the tumor suppressor CASZ1 required for transcriptional regulation and growth suppression

1 reference

12 December 2020

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

1 reference

12 December 2020

Strelka: accurate somatic small-variant calling from sequenced tumor-normal sample pairs

1 reference

12 December 2020

Validation of methods for oropharyngeal cancer HPV status determination in US cooperative group trials

1 reference

12 December 2020

Loss of heterozygosity (LOH) profiles--validated risk predictors for progression to oral cancer

1 reference

12 December 2020

ZNF750 is expressed in differentiated keratinocytes and regulates epidermal late differentiation genes

1 reference

12 December 2020

LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets

1 reference

12 December 2020

Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy.

1 reference

12 December 2020

Cycles of ubiquitination and deubiquitination critically regulate growth factor-mediated activation of Akt signaling

1 reference

12 December 2020

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

1 reference

12 December 2020

Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers

1 reference

12 December 2020

The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter

1 reference

12 December 2020

Mutational heterogeneity in cancer and the search for new cancer-associated genes

1 reference

12 December 2020

The role of cytidine deaminases on innate immune responses against human viral infections.

1 reference

12 December 2020

Signatures of mutational processes in human cancer

1 reference

12 December 2020

Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability

1 reference

12 December 2020

TGF-β activation and function in immunity

1 reference

12 December 2020

Activating FGFR3 mutations cause mild hyperplasia in human skin, but are insufficient to drive benign or malignant skin tumors.

1 reference

12 December 2020

Human viral oncogenesis: a cancer hallmarks analysis

1 reference

12 December 2020

APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development

1 reference

12 December 2020

Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas

1 reference

12 December 2020

Characterization of Bbx, a member of a novel subfamily of the HMG-box superfamily together with Cic.

1 reference

12 December 2020

Mapping of HPV transcripts in four human cervical lesions using RNAseq suggests quantitative rearrangements during carcinogenic progression

1 reference

12 December 2020

Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities

1 reference

12 December 2020

Novel functions of viral anti-apoptotic factors

1 reference

12 December 2020

Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes

1 reference

12 December 2020

Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B

1 reference

12 December 2020

Multiple functions of DDX3 RNA helicase in gene regulation, tumorigenesis, and viral infection

1 reference

12 December 2020

APOBEC3A and 3C decrease human papillomavirus 16 pseudovirion infectivity.

1 reference

12 December 2020

Comprehensive genomic characterization of head and neck squamous cell carcinomas

1 reference

12 December 2020

Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing.

1 reference

12 December 2020

HPV16 E5 deregulates the autophagic process in human keratinocytes

1 reference

12 December 2020

Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma

1 reference

12 December 2020

Targeting cancer by binding iron: Dissecting cellular signaling pathways

1 reference

12 December 2020

Genetic Landscape of Human Papillomavirus-Associated Head and Neck Cancer and Comparison to Tobacco-Related Tumors

1 reference

12 December 2020

A panoply of errors: polymerase proofreading domain mutations in cancer

1 reference

12 December 2020

DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution

1 reference

12 December 2020

TRAF3 signaling: Competitive binding and evolvability of adaptive viral molecular mimicry.

1 reference

12 December 2020

The Ensembl Variant Effect Predictor

1 reference

12 December 2020

PiggyBac Transposon-Mediated Mutagenesis in Rats Reveals a Crucial Role of Bbx in Growth and Male Fertility.

1 reference

12 December 2020

mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model.

1 reference

12 December 2020

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

1 reference

12 December 2020

The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription

1 reference

12 December 2020

Mutational signatures associated with tobacco smoking in human cancer

1 reference

12 December 2020

ZNF750 is a lineage-specific tumour suppressor in squamous cell carcinoma

1 reference

12 December 2020

Manipulation of the innate immune response by human papillomaviruses

1 reference

12 December 2020

Evasion of host immune defenses by human papillomavirus

1 reference

12 December 2020

DDX3 directly regulates TRAF3 ubiquitination and acts as a scaffold to co-ordinate assembly of signalling complexes downstream from MAVS.

1 reference

12 December 2020

Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.

1 reference

12 December 2020

Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor

1 reference

12 December 2020

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations

1 reference

12 December 2020

Genetic alterations in TRAF3 and CYLD that regulate nuclear factor κB and interferon signaling define head and neck cancer subsets harboring human papillomavirus.

1 reference

12 December 2020

TRAF3/CYLD mutations identify a distinct subset of human papillomavirus-associated head and neck squamous cell carcinoma

1 reference

12 December 2020

CYLD, A20 and OTULIN deubiquitinases in NF-κB signaling and cell death: so similar, yet so different

1 reference

12 December 2020

Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations

1 reference

12 December 2020

Histone H3 lysine 4 methyltransferase KMT2D.

1 reference

12 December 2020

The HPV E6/E7 Oncogenes: Key Factors for Viral Carcinogenesis and Therapeutic Targets.

1 reference

12 December 2020

Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression

1 reference

12 December 2020

Epigenetic Alterations in Human Papillomavirus-Associated Cancers

1 reference

12 December 2020

HPV16 E7 Genetic Conservation Is Critical to Carcinogenesis

1 reference

12 December 2020

Prevalence of high-risk human papillomavirus infection and cancer gene mutations in nonmalignant tonsils

1 reference

12 December 2020

Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis

1 reference

12 December 2020

The role of Nuclear Factor-kappa B signaling in human cervical cancer

1 reference

12 December 2020

NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma.

1 reference

12 December 2020

The Role of E6 Spliced Isoforms (E6*) in Human Papillomavirus-Induced Carcinogenesis

1 reference

12 December 2020

Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-dependent Protein Degradation

1 reference

12 December 2020

Induction of interferon kappa in human papillomavirus type 16 infection by transforming growth factor beta-induced promoter demethylation.

1 reference

12 December 2020

KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis.

1 reference

12 December 2020

miR-501 is upregulated in cervical cancer and promotes cell proliferation, migration and invasion by targeting CYLD.

1 reference

12 December 2020

Systematic Functional Annotation of Somatic Mutations in Cancer.

1 reference

12 December 2020

Inhibition of TGF-β and NOTCH Signaling by Cutaneous Papillomaviruses.

1 reference

12 December 2020

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.

1 reference

12 December 2020

Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein Network

1 reference

12 December 2020

Identifiers

DOI

10.1101/GR.241141.118

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30563911%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

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15 April 2020

PubMed publication ID

30563911

1 reference