(Q90676375)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

title

Tilorone: a Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and beyond (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

ChEBI release 2020-05-28

1 reference

1

Sean Ekins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

author name string

Thomas R Lane

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Peter B Madrid

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

publication date

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

published in

Pharmaceutical Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

page(s)

71

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

Effects of tilorone hydrochloride on experimental flavivirus infections in mice

15 April 2020

cites work

1 reference

12 December 2020

Comparison of antiviral properties in mice of bis-pyrrolidinoacetamido-fluorenone (MLU-B75), bis-dipropylaminoacetamido-fluorenone (MLU-B76), and tilorone hydrochloride

1 reference

12 December 2020

Inhibition of Herpesvirus Deoxyribonucleic Acid and Protein Synthesis by Tilorone Hydrochloride

1 reference

12 December 2020

The Effect of Tilorone Hydrochloride on the Growth of Several Animal Viruses in Tissue Cultures

1 reference

12 December 2020

Evaluation of various analogues of tilorone hydrochloride against Venezuelan equine encephalitis virus in mice

1 reference

12 December 2020

Antiviral Activity of 10-Carboxymethyl-9-Acridanone

1 reference

12 December 2020

Clinical research on the tolerance for and the interferon-inducing activity of amiksin

1 reference

12 December 2020

Tilorone hydrochloride: an orally active antiviral agent.

1 reference

12 December 2020

Tilorone hydrochloride: mode of action

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12 December 2020

Tilorone Hydrochloride: Human Toxicity and Interferon Stimulation

1 reference

12 December 2020

Tilorone acts as a lysosomotropic agent in fibroblasts

1 reference

12 December 2020

Adjuvant Effects of Tilorone Hydrochloride (Analog 11,567) with Inactivated Venezuelan Equine Encephalomyelitis Virus Vaccine

1 reference

12 December 2020

Tilorone-induced lysosomal storage of sulphated glycosaminoglycans can be separated from tilorone-induced enhancement of lysosomal enzyme secretion

1 reference

12 December 2020

Russian experience in screening, analysis, and clinical application of novel interferon inducers

1 reference

12 December 2020

[Evaluation of amyxin effect in prophylaxis of acute respiratory viral infections]

1 reference

12 December 2020

[Effect of amyxin--a domestic analog of tilorone--on characteristics of interferon and immune status of man]

1 reference

12 December 2020

Virus-inhibitory effect of a yeast RNA-tilorone molecular complex in cell cultures

1 reference

12 December 2020

[Evaluation of amixine reactivity and efficacy for prophylaxis of acute respiratory tract infections].

1 reference

12 December 2020

NK cells mediate increase of phagocytic activity but not of proinflammatory cytokine (interleukin-6 [IL-6], tumor necrosis factor alpha, and IL-12) production elicited in splenic macrophages by tilorone treatment of mice during acute systemic candid

1 reference

12 December 2020

Use of amixin in the therapy and prevention of some viral infections

1 reference

12 December 2020

Immunomodulators in the prevention of acute respiratory viral infections.

1 reference

12 December 2020

Antiviral activity of an interferon inducer amixin in experimental West Nile Fever

1 reference

12 December 2020

Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury

1 reference

12 December 2020

Chloroquine transport via the malaria parasite's chloroquine resistance transporter

1 reference

12 December 2020

Antiviral properties, metabolism, and pharmacokinetics of a novel azolo-1,2,4-triazine-derived inhibitor of influenza A and B virus replication.

1 reference

12 December 2020

Pattern recognition receptors and inflammation

1 reference

12 December 2020

Effect of tilorone and its analogues on the change of mitochondrial potential of rat hepatocytes

1 reference

12 December 2020

A systematic screen of FDA-approved drugs for inhibitors of biological threat agents

1 reference

12 December 2020

RIG-I in RNA virus recognition

1 reference

12 December 2020

The cytokine storm of severe influenza and development of immunomodulatory therapy

1 reference

12 December 2020

An Effective Synthesis Method for Tilorone Dihydrochloride with Obvious IFN-α Inducing Activity.

1 reference

12 December 2020

The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses

1 reference

12 December 2020

Machine learning models identify molecules active against the Ebola virus in vitro

1 reference

12 December 2020

Evaluation of Ebola Virus Inhibitors for Drug Repurposing.

1 reference

12 December 2020

A Systems Approach Reveals MAVS Signaling in Myeloid Cells as Critical for Resistance to Ebola Virus in Murine Models of Infection

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12 December 2020

Antiviral activity of cationic amphiphilic drugs

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12 December 2020

Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection

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12 December 2020

Ebola Virus Bayesian Machine Learning Models Enable New in Vitro Leads

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12 December 2020

Drug repurposing for new, efficient, broad spectrum antivirals

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12 December 2020

High-throughput Screening and Identification of Potent Broad-spectrum Inhibitors of Coronaviruses

1 reference

12 December 2020

Ebola Virus: Pathogenesis and Countermeasure Development

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12 December 2020

Zika Virus Infection - After the Pandemic

1 reference

12 December 2020

Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine

1 reference

12 December 2020

Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection

1 reference

12 December 2020

First Case of 2019 Novel Coronavirus in the United States

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12 December 2020

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

1 reference

12 December 2020

Tilorone: A Broad-Spectrum Antiviral For Emerging Viruses

1 reference

12 December 2020

10.1007/S11095-020-02799-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

15 April 2020

COVIDWHO ID

covidwho-18423

0 references

1125901379

1 reference

Dimensions COVID-19 publications, datasets and clinical trials

DOI

10.6084/M9.FIGSHARE.11961063

28 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32215760%20AND%20SRC:MED&resulttype=core&format=json