(Q34066937)

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Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19076458%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury (English)

1 reference

Europe PubMed Central

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18 January 2020

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4

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18 January 2020

S Thomas Carmichael

8

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18 January 2020

12

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18 January 2020

14

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18 January 2020

18

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18 January 2020

23

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18 January 2020

15

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Sashwati Roy

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18 January 2020

Daniel Geschwind

11

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Daniel H Geschwind

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18 January 2020

Gregg L. Semenza

22

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Gregg L Semenza

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18 January 2020

Harley I Kornblum

9

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Harley Kornblum

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18 January 2020

author name string

Rajiv R Ratan

1

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18 January 2020

Ambreena Siddiq

2

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18 January 2020

Leila Aminova

3

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18 January 2020

Stephen McConoughey

5

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18 January 2020

Ksenia Karpisheva

6

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18 January 2020

Hsin-Hwa Lee

7

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18 January 2020

Giovanni Coppola

10

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18 January 2020

Natalya Smirnova

13

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18 January 2020

Chandan Sen

16

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18 January 2020

Michael S Beattie

17

1 reference

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18 January 2020

Martin Grumet

19

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18 January 2020

Dongming Sun

20

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Europe PubMed Central

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18 January 2020

Robert S Freeman

21

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18 January 2020

language of work or name

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publication date

1 December 2008

1 reference

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18 January 2020

Annals of the New York Academy of Sciences

1 reference

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18 January 2020

1147

1 reference

Europe PubMed Central

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18 January 2020

383-394

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19076458%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

LPS induces hypoxia-inducible factor 1 activation in macrophage-differentiated cells in a reactive oxygen species-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Harnessing hypoxic adaptation to prevent, treat, and repair stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Hypoxia-inducible factor 1 (HIF-1) pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Future of neuroprotection for acute stroke: in the aftermath of the SAINT trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Regulation of HIF: prolyl hydroxylases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Molecular modeling of DNA cross-linking analogues based on the azinomycin scaffold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Targeting hypoxia-inducible factor (HIF) as a therapeutic strategy for CNS disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

The GGA proteins: key players in protein sorting at the trans-Golgi network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Translation of ischemic preconditioning to the patient: prolyl hydroxylase inhibition and hypoxia inducible factor-1 as novel targets for stroke therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Tilorone hydrochloride: an orally active antiviral agent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

Tilorone hydrochloride: The drug profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

5 July 2018

A semiautomated method for measuring brain infarct volume.

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1427.033

21 January 2018

Osteopontin-deficient mice exhibit less inflammation, greater tissue damage, and impaired locomotor recovery from spinal cord injury compared with wild-type controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

28 October 2018

Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

28 October 2018

Nicotinamide reduces infarction up to two hours after the onset of permanent focal cerebral ischemia in Wistar rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

28 October 2018

The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921907

28 October 2018

Usages of interferon and interferon inducers in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/19076458

12 December 2020

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Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19076458

12 December 2020

based on heuristic

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Teaching old drugs new tricks. Meeting of the Neurodegeneration Drug Screening Consortium, 7-8 April 2002, Washington, DC, USA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19076458

12 December 2020

based on heuristic

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10.1196/ANNALS.1427.033

1 reference

Europe PubMed Central

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18 January 2020

PMC publication ID

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Europe PubMed Central

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18 January 2020

PubMed publication ID

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Europe PubMed Central

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18 January 2020

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