(Q36842794)

16 August 2017

1 reference

title

Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. (English)

1 reference

16 August 2017

0 references

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1

Gregg L Semenza

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16 August 2017

language of work or name

English

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publication date

1 July 2007

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16 August 2017

number of pages

9

1 reference

inferred from page(s)

published in

Biochemical Journal

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16 August 2017

volume

405

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16 August 2017

issue

1

1 reference

16 August 2017

page(s)

1-9

1 reference

Identification of an angiogenic mitogen selective for endocrine gland endothelium

16 August 2017

cites work

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Lactase gene transcription is activated in response to hypoxia in intestinal epithelial cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Mammalian subunit IV isoforms of cytochrome c oxidase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Oxygen-regulated Transferrin Expression Is Mediated by Hypoxia-inducible Factor-1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Target validation in hypoxia-induced vascular remodeling using transcriptome/metabolome analysis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identification of hypoxia-response element in the human endothelial nitric-oxide synthase gene promoter

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Induction ofID2Expression by Hypoxia-inducible Factor-1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Communication between mitochondria and the nucleus in regulation of cytochrome genes in the yeast Saccharomyces cerevisiae

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia induces transcription factor ETS-1 via the activity of hypoxia-inducible factor-1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Transferrin receptor gene expression and transferrin-bound iron uptake are increased during postischemic rat liver reperfusion

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Oxygen regulation of anaerobic and aerobic genes mediated by a common factor in yeast

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Midkine is regulated by hypoxia and causes pulmonary vascular remodeling.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxic induction of prolyl 4-hydroxylase alpha (I) in cultured cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

The gene encoding human retinoic acid-receptor-related orphan receptor alpha is a target for hypoxia-inducible factor 1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxic activation of the atrial natriuretic peptide gene promoter through direct and indirect actions of hypoxia-inducible factor-1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Nur77 activated by hypoxia-inducible factor-1alpha overproduces proopiomelanocortin in von Hippel-Lindau-mutated renal cell carcinoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Direct Transcriptional Up-regulation of Cyclooxygenase-2 by Hypoxia-Inducible Factor (HIF)-1 Promotes Colorectal Tumor Cell Survival and Enhances HIF-1 Transcriptional Activity during Hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-inducible factor 1 transactivates the human leptin gene promoter

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-induced activation of the retinoic acid receptor-related orphan receptor alpha4 gene by an interaction between hypoxia-inducible factor-1 and Sp1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identification of a hypoxia response element in the transferrin receptor gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3)

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Isoforms of yeast cytochrome c oxidase subunit V affect the binuclear reaction center and alter the kinetics of interaction with the isoforms of yeast cytochrome c.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Characterization of the α 1B -adrenergic receptor gene promoter region and hypoxia regulatory elements in vascular smooth muscle

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

HIF-1alpha is essential for myeloid cell-mediated inflammation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Evolution. Tracing oxygen's imprint on earth's metabolic evolution.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Coordinate reciprocal trends in glycolytic and mitochondrial transcript accumulations during the in vitro differentiation of human myoblasts.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Up-regulation of 94-kDa glucose-regulated protein by hypoxia-inducible factor-1 in human endothelial cells in response to hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia regulates beta-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identification and characterization of the hypoxia-responsive element of the human placental 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Oncogenic alterations of metabolism

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Regulation of the chemokine receptor CXCR4 by hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Induction of HIF-1alpha in response to hypoxia is instantaneous

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial apoptotic pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Extramitochondrial ATP/ADP-ratios regulate cytochrome c oxidase activity via binding to the cytosolic domain of subunit IV

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia‐inducible factor‐1 and activator protein‐1 modulate the upregulation of CYP3A6 induced by hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Induction of the Plasminogen Activator Inhibitor-1 Gene Expression by Mild Hypoxia Via a Hypoxia Response Element Binding the Hypoxia-Inducible Factor-1 in Rat Hepatocytes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1042/BJ20070389

Identifiers

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30 July 2022