Wikidata

(Q909409)

English

KIT proto-oncogene, receptor tyrosine kinase

mammalian protein found in Homo sapiens

  • KIT
  • proto-oncogene tyrosine-protein kinase Kit
  • mast/stem cell growth factor receptor Kit
  • PBT
  • soluble KIT variant 1
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • tyrosine-protein kinase Kit
  • p145 c-kit
  • piebald trait protein
  • proto-oncogene c-Kit
  • c-Kit protooncogene
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
  • Proto-Oncogene Proteins c-kit
  • CD117
In more languages
default values for all languages
No label defined

No description defined

Statements

part of
genetic association
roan
0 references
molecular function
protein binding
determination method
IPI
10 references
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721
determination method
IPI
retrieved
8 April 2019
stated in
The direct association of the multiple PDZ domain containing proteins (MUPP-1) with the human c-Kit C-terminus is regulated by tyrosine kinase activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721
determination method
IPI
retrieved
8 April 2019
stated in
Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721
determination method
IPI
retrieved
8 April 2019
stated in
The receptor protein tyrosine phosphatase, PTP-RO, is upregulated during megakaryocyte differentiation and Is associated with the c-Kit receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721
determination method
IPI
retrieved
8 April 2019
stated in
Formation of signal transfer complexes between stem cell and platelet-derived growth factor receptors and SH2 domain proteins in vitro
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721
determination method
IPI
retrieved
8 April 2019
stated in
The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721
determination method
IPI
retrieved
8 April 2019
stated in
Inhibition of SH2 domain/phosphoprotein association by a nonhydrolyzable phosphonopeptide
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721
determination method
IPI
retrieved
8 April 2019
stated in
Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721
determination method
IPI
retrieved
8 April 2019
stated in
Identification of Tyr900 in the kinase domain of c-Kit as a Src-dependent phosphorylation site mediating interaction with c-Crk
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721
determination method
IPI
cell component
biological process
physically interacts with

Identifiers

MeSH descriptor ID
D019009
subject named as
Proto-Oncogene Proteins c-kit
0 references
Freebase ID
/m/028c5ph
0 references
PDB structure ID
 
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