(Q24318673)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0038109

KIT proto-oncogene, receptor tyrosine kinase

1 reference

mast cell differentiation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1

Robert Roskoski

0 references

language of work or name

English

0 references

publication date

11 November 2005

0 references

number of pages

13

1 reference

Biochemical and Biophysical Research Communications

inferred from page(s)

published in

0 references

volume

337

0 references

page(s)

1-13

0 references

issue

1

0 references

cites work

Phospholipase C-gamma as a signal-transducing element

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Mast cells stimulated by membrane-bound, but not soluble, steel factor are dependent on phospholipase C activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Signal transduction via the stem cell factor receptor/c-Kit

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Steel locus defines new multipotent growth factor

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

STI-571: an anticancer protein-tyrosine kinase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Src protein-tyrosine kinase structure and regulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Src kinase regulation by phosphorylation and dephosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Lyn contributes to regulation of multiple Kit-dependent signaling pathways in murine bone marrow mast cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Identification of Tyr900 in the kinase domain of c-Kit as a Src-dependent phosphorylation site mediating interaction with c-Crk

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

The anaemia of cancer: death by a thousand cuts

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Isoforms of c-KIT differ in activation of signalling pathways and transformation of NIH3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Consequences of exclusive expression in vivo of Kit-ligand lacking the major proteolytic cleavage site

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Lyn associates with the juxtamembrane region of c-Kit and is activated by stem cell factor in hematopoietic cell lines and normal progenitor cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Direct association of Csk homologous kinase (CHK) with the diphosphorylated site Tyr568/570 of the activated c-KIT in megakaryocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Substrate hydrolysis by matrix metalloproteinase-9.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Stem cell factor/c-kit signaling promotes the survival, migration, and capillary tube formation of human umbilical vein endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Signalling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl).

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

The phosphoinositide (PI) 3-kinase family

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Normal and oncogenic forms of the receptor tyrosine kinase kit.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021

Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2005.08.055

7 January 2021