(Q24305445)

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Mechanism of activation of human c-KIT kinase by internal tandem duplications of the juxtamembrane domain and point mutations at aspartic acid 816

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Mechanism of activation of human c-KIT kinase by internal tandem duplications of the juxtamembrane domain and point mutations at aspartic acid 816 (English)

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KIT proto-oncogene, receptor tyrosine kinase

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GOA release 2020-03-11

protein autophosphorylation

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GOA release 2020-03-11

3

object named as

Hyung Hoan Lee

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author name string

Soo Young Kim

1

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Jamie J Kang

2

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Jenny J Kang

4

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Bokyung Kim

5

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Chan-Gil Kim

6

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Tae-Kyu Park

7

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Hyun Kang

8

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language of work or name

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publication date

1 July 2011

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Biochemical and Biophysical Research Communications

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410

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2

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224-8

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Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor

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https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Fyn kinase acts upstream of Shp2 and p38 mitogen-activated protein kinase to promote chemotaxis of mast cells towards stem cell factor

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of c-kit/SCF in cause and treatment of gastrointestinal stromal tumors (GIST).

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Kit signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Assignment of the inter- and intramolecular disulfide linkages in recombinant human macrophage colony stimulating factor using fast atom bombardment mass spectrometry.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural basis for stem cell factor–KIT signaling and activation of class III receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

STAT3 activation is required for Asp(816) mutant c-Kit induced tumorigenicity

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysing c-kit internalization using a functional c-kit-EGFP chimera containing the fluorochrome within the extracellular domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

A new c-kit mutation in a case of aggressive mast cell disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of a c-kit product complex reveals the basis for kinase transactivation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Biology of gastrointestinal stromal tumors: KIT mutations and beyond

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Dimerization of Kit-ligand and efficient cell-surface presentation requires a conserved Ser-Gly-Gly-Tyr motif in its transmembrane domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Mast cells and mastocytosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Signal transducer and activator of transcription 3 activation is required for Asp(816) mutant c-Kit-mediated cytokine-independent survival and proliferation in human leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBRC.2011.05.111

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1016/J.BBRC.2011.05.111

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