(Q91216849)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30680958%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

title

Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin (English)

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20 April 2020

9

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20 April 2020

Torsten Steinmetzer

10

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20 April 2020

author name string

Thuy Van Lam van

1

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20 April 2020

Teodora Ivanova

2

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20 April 2020

Kornelia Hardes

3

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20 April 2020

Miriam Ruth Heindl

4

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20 April 2020

Rory E Morty

5

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20 April 2020

Eva Böttcher-Friebertshäuser

6

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20 April 2020

Iris Lindberg

7

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20 April 2020

Manuel E Than

8

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20 April 2020

publication date

20 February 2019

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20 April 2020

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20 April 2020

volume

14

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20 April 2020

issue

6

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20 April 2020

page(s)

673-685

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Peptide therapeutics: current status and future directions

20 April 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Protease inhibitor therapy for hepatitis C virus-infection.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Design and synthesis of potent and selective macrocyclic thrombin inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa-Tissue Factor Complex.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Neutral macrocyclic factor VIIa inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Development of new cyclic plasmin inhibitors with excellent potency and selectivity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Optimization of Cyclic Plasmin Inhibitors: From Benzamidines to Benzylamines

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Furin at the cutting edge: from protein traffic to embryogenesis and disease

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

The biology and therapeutic targeting of the proprotein convertases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

On the cutting edge of proprotein convertase pharmacology: from molecular concepts to clinical applications

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Role of subtilisin-like convertases in cadherin processing or the conundrum to stall cadherin function by convertase inhibitors in cancer therapy

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Proprotein convertase furin inhibits matrix metalloproteinase 13 in a TGFβ-dependent manner and limits osteoarthritis in mice.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Cationic Cell-Penetrating Peptides Are Potent Furin Inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Macrocyclization of a potent PACE4 inhibitor: Benefits and limitations.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Engineering a Constrained Peptidic Scaffold towards Potent and Selective Furin Inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

X-ray structures of the proprotein convertase furin bound with substrate analog inhibitors reveal substrate specificity determinants beyond the S4 pocket.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Efficient delivery of cyclic peptides into mammalian cells with short sequence motifs

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Cell-permeable bicyclic peptide inhibitors against intracellular proteins

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Cell-penetrating peptides as delivery vehicles for biology and medicine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Novel Furin Inhibitors with Potent Anti-infectious Activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Global analysis of peptide cyclization efficiency

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

New substrate analogue furin inhibitors derived from 4-amidinobenzylamide

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

17 The kinetics of reversible tight-binding inhibition

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Optimization of Substrate-Analogue Furin Inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

X-ray Structures of Human Furin in Complex with Competitive Inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Immunological Features of Respiratory Syncytial Virus-Caused Pneumonia-Implications for Vaccine Design

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Proteolytic activation of respiratory syncytial virus fusion protein. Cleavage at two furin consensus sequences

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Virokinin, a bioactive peptide of the tachykinin family, is released from the fusion protein of bovine respiratory syncytial virus

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Entry, Replication, Immune Evasion, and Neurotoxicity of Synthetically Engineered Bat-Borne Mumps Virus

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

The effect of cell penetrating peptides on transfection activity and cytotoxicity of polyallylamine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Identification of an atypical calcium-dependent calmodulin binding site on the C-terminal domain of GluN2A

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

ID29: a high-intensity highly automated ESRF beamline for macromolecular crystallography experiments exploiting anomalous scattering

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

The Upgrade Programme for the Structural Biology beamlines at the European Synchrotron Radiation Facility – High throughput sample evaluation and automation

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

https://api.crossref.org/works/10.1002%2FCMDC.201800807

1 reference

7 January 2021

https://api.crossref.org/works/10.1002%2FCMDC.201800807

1 reference

7 January 2021

Overview of the CCP4 suite and current developments

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Features and development of Coot

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

New low-viscosity overlay medium for viral plaque assays

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201800807

7 January 2021

Identifiers

DOI

10.1002/CMDC.201800807

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30680958%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

1 reference