(Q35875579)

English

Role of subtilisin-like convertases in cadherin processing or the conundrum to stall cadherin function by convertase inhibitors in cancer therapy

scientific article published in March 2004

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

Role of subtilisin-like convertases in cadherin processing or the conundrum to stall cadherin function by convertase inhibitors in cancer therapy (English)

1 reference

Europe PubMed Central

10 August 2017

author name string

E J Müller

1

1 reference

Europe PubMed Central

10 August 2017

R Caldelari

2

1 reference

Europe PubMed Central

10 August 2017

H Posthaus

3

1 reference

Europe PubMed Central

10 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 March 2004

1 reference

Europe PubMed Central

10 August 2017

Journal of Molecular Histology

1 reference

Europe PubMed Central

10 August 2017

35

1 reference

Europe PubMed Central

10 August 2017

3

1 reference

Europe PubMed Central

10 August 2017

263-275

1 reference

Europe PubMed Central

10 August 2017

Localization of prohormone convertases 1/3 and 2 in the human pituitary gland and pituitary adenomas: analysis by immunohistochemistry, immunoelectron microscopy, and laser scanning microscopy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haploinsufficiency of desmoplakin causes a striate subtype of palmoplantar keratoderma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E-Cadherin mediates MMP down-regulation in highly invasive bronchial tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of p0071 to desmosomes and adherens junctions is mediated by different protein domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caught up in a Wnt storm: Wnt signaling in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of c-MYC as a target of the APC pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desmoplakin is essential in epidermal sheet formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E-cadherin germline mutations in familial gastric cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired fertility in mice deficient for the testicular germ-cell protease PC4

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of the E-cadherin-catenin complex in mitotic Madin-Darby canine kidney epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proprotein convertases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased synthesis but decreased processing of neuronal proCCK in prohormone convertase 2 and 7B2 knockout animals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New aspects of Wnt signaling pathways in higher vertebrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common human skin tumour is caused by activating mutations in beta-catenin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro-protein convertase gene expression in human breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of selectivity of alpha1-antitrypsin variant by mutagenesis in its reactive site loop against proprotein convertase. A crucial role of the P4 arginine in PACE4 inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of the human E-cadherin (CDH1) gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APC mutations occur early during colorectal tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear particles containing RNA polymerase III complexes associated with the junctional plaque protein plakophilin 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated furin expression in aggressive human head and neck tumors and tumor cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MYC oncogene as a cancer drug target

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human plakoglobin gene localizes on chromosome 17q21 and is subjected to loss of heterozygosity in breast and ovarian cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Wnt signaling pathway and its role in tumor development

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell contact-dependent signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PML is a target gene of beta-catenin and plakoglobin, and coactivates beta-catenin-mediated transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for cadherins in tissue formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice expressing a mutant desmosomal cadherin exhibit abnormalities in desmosomes, proliferation, and epidermal differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desmosomes and disease: an update

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are desmosomes more than tethers for intermediate filaments?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Germline E-cadherin Gene (CDH1) Mutations Predispose to Familial Gastric Cancer and Colorectal Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curbing activation: proprotein convertases in homeostasis and pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trangenic misexpression of the differentiation-specific desmocollin isoform 1 in basal keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that PC2 is the endogenous pro-neurotensin convertase in rMTC 6-23 cells and that PC1- and PC2-transfected PC12 cells differentially process pro-neurotensin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular targeting and structural conservation of a prohormone-processing endoprotease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for beta-catenin in anterior-posterior axis formation in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear localization of beta-catenin and plakoglobin in primary and metastatic human colonic carcinomas, colonic adenomas, and normal colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changing neighbours, changing behaviour: cell adhesion molecule-mediated signalling during tumour progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proprotein cleavage of E-cadherin by furin in baculovirus over-expression system: potential role of other convertases in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The differential processing of proenkephalin A in mouse and human breast tumour cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suprabasal alpha6beta4 integrin expression in epidermis results in enhanced tumourigenesis and disruption of TGFbeta signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desmosomes: intercellular adhesive junctions specialized for attachment of intermediate filaments.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desmoglein isoform distribution affects stratum corneum structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of PACE4 in chemically induced carcinomas is associated with spindle cell tumor conversion and increased invasive ability.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-terminal deletion in a desmosomal cadherin causes the autosomal dominant skin disease striate palmoplantar keratoderma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional regulation of semaphorin receptors by proprotein convertases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eukaryotic protein processing: endoproteolysis of precursor proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-talk between adherens junctions and desmosomes depends on plakoglobin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An alpha-E-catenin gene trap mutation defines its function in preimplantation development

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor (VEGF)-C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellular proteolytic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desmosomal adhesion inhibits invasive behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New functions for the matrix metalloproteinases in cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cadherin-catenin adhesion system in signaling and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced expression of plakoglobin correlates with adverse outcome in patients with neuroblastoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correct proteolytic cleavage is required for the cell adhesive function of uvomorulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A causal role for E-cadherin in the transition from adenoma to carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promoter characterization of the novel human matrix metalloproteinase-26 gene: regulation by the T-cell factor-4 implies specific expression of the gene in cancer cells of epithelial origin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of transforming growth factor beta 1 precursor by human furin convertase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta signaling in tumor suppression and cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Catenin regulates vascular endothelial growth factor expression in colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of beta-catenin affects mouse development at gastrulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of desmosome assembly in MDCK epithelial cells: coordination of membrane core and cytoplasmic plaque domain assembly at the plasma membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cadherin adhesive activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cadherin-catenin complex: protein interactions and their implications for cadherin function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory potency and specificity of subtilase-like pro-protein convertase (SPC) prodomains

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intercellular adhesion, signalling and the cytoskeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased proteolytic processing of protein tyrosine phosphatase mu in confluent vascular endothelial cells: the role of PC5, a member of the subtilisin family

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plakoglobin suppresses epithelial proliferation and hair growth in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desmosomal adhesion: structural basis, molecular mechanism and regulation (Review).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Key peptide processing enzymes are expressed by breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential interaction of plakoglobin and beta-catenin with the ubiquitin-proteasome system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paired basic/Furin-like proprotein convertase cleavage of Pro-BMP-1 in the trans-Golgi network

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stabilization of beta-catenin by genetic defects in melanoma cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plakophilins 1a and 1b: widespread nuclear proteins recruited in specific epithelial cells as desmosomal plaque components

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cadherins and their connections: adhesion junctions have broader functions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cadherin and catenin alterations in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Notch1 receptor is cleaved constitutively by a furin-like convertase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mouse matrix metalloproteinase, epilysin (MMP-28), is alternatively spliced and processed by a furin-like proprotein convertase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of invasiveness in squamous cell carcinoma cells overexpressing desmosomal cadherins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Re-expression of E-cadherin, alpha-catenin and beta-catenin, but not of gamma-catenin, in metastatic tissue from breast cancer patients [seecomments]

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional interaction of beta-catenin with the transcription factor LEF-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WNT targets. Repression and activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

fur gene expression as a discriminating marker for small cell and nonsmall cell lung carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthetic processing of the pro-alpha 1(V)2pro-alpha 2(V) collagen heterotrimer by bone morphogenetic protein-1 and furin-like proprotein convertases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of furin-mediated processing results in suppression of astrocytoma cell growth and invasiveness.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proprotein convertase PC5A and a metalloprotease are involved in the proteolytic processing of the neural adhesion molecule L1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution and regulation of proconvertases PC1 and PC2 in human pituitary adenomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of desmoglein I and plakoglobin in skin carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatostatin-14, somatostatin-28, and prosomatostatin[1-10] are independently and efficiently processed from prosomatostatin in the constitutive secretory pathway in islet somatostatin tumor cells (1027B2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic heart and skin defects in mice lacking plakoglobin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Weaving a tangled web: the interconnected cytoskeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malignant conversion of non-tumorigenic murine skin keratinocytes overexpressing PACE4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The alpha isoform of protein kinase C is involved in signaling the response of desmosomes to wounding in cultured epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis of calcium-induced E-cadherin rigidification and dimerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel insights into cadherin processing by subtilisin-like convertases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase(s) mediate(s) NO-induced dissociation of beta-catenin from membrane bound E-cadherin and formation of nuclear beta-catenin/LEF-1 complex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15339046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/B:HIJO.0000032358.51866.A2

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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