(Q27700845)

1

object named as

Kornelia Hardes

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author name string

Gero L Becker

2

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Yinghui Lu

3

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Sven O Dahms

4

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Susanne Köhler

5

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Wolfgang Beyer

6

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Hiroyuki Yamamoto

8

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Iris Lindberg

9

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Lisa Walz

10

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Veronika von Messling

11

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Manuel E Than

12

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Wolfgang Garten

13

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Torsten Steinmetzer

Furin at the cutting edge: from protein traffic to embryogenesis and disease

14

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publication date

July 2015

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published in

ChemMedChem

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volume

10

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issue

7

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page(s)

1218-31

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cites work

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The biology and therapeutic targeting of the proprotein convertases

21 January 2018

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Knock-out mouse models of proprotein convertases: unique functions or redundancy?

21 January 2018

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Limited redundancy of the proprotein convertase furin in mouse liver

21 January 2018

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The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo

21 January 2018

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Protection against anthrax toxemia by hexa-D-arginine in vitro and in vivo

21 January 2018

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On the cutting edge of proprotein convertase pharmacology: from molecular concepts to clinical applications

21 January 2018

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Viral envelope glycoprotein processing by proprotein convertases

21 January 2018

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Phase I trial of "bi-shRNAi(furin)/GMCSF DNA/autologous tumor cell" vaccine (FANG) in advanced cancer

21 January 2018

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Summary of bi-shRNA/GM-CSF augmented autologous tumor cell immunotherapy (FANG™) in advanced cancer of the liver

21 January 2018

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Inhibitors of proprotein convertases

21 January 2018

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Inhibition of furin by polyarginine-containing peptides: nanomolar inhibition by nona-D-arginine

21 January 2018

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Synthetic small molecule furin inhibitors derived from 2,5-dideoxystreptamine

21 January 2018

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Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics

21 January 2018

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Optimization of furin inhibitors to protect against the activation of influenza hemagglutinin H5 and Shiga toxin.

21 January 2018

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Design, synthesis, and structure-activity relationship studies of a potent PACE4 inhibitor

21 January 2018

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Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases

21 January 2018

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X-ray Structures of Human Furin in Complex with Competitive Inhibitors

21 January 2018

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The crystal structure of the proprotein processing proteinase furin explains its stringent specificity

21 January 2018

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Conformation of Polypeptides and Proteins

21 January 2018

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Thermofluor-based high-throughput stability optimization of proteins for structural studies

21 January 2018

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Tropism illuminated: lymphocyte-based pathways blazed by lethal morbillivirus through the host immune system

21 January 2018

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21 January 2018

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Anthrax lethal and edema toxins in anthrax pathogenesis

21 January 2018

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Anthrax toxin: receptor binding, internalization, pore formation, and translocation

21 January 2018

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Novel approaches to the treatment of systemic anthrax

21 January 2018

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21 January 2018

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The pathology of diphtheria

21 January 2018

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The genesis of a pandemic influenza virus.

21 January 2018

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Host cell proteases controlling virus pathogenicity

21 January 2018

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MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201500103

Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors

21 January 2018

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Canine distemper virus and measles virus fusion glycoprotein trimers: partial membrane-proximal ectodomain cleavage enhances function

21 January 2018

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Pathogenesis and immunopathology of systemic and nervous canine distemper

21 January 2018

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A ferret model of canine distemper virus virulence and immunosuppression.

21 January 2018

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Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones

21 January 2018

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Structural basis of substrate specificity in the serine proteases

21 January 2018

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Update 1 of: Proteases universally recognize beta strands in their active sites

21 January 2018

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Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bio

21 January 2018

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Discovery of small-molecule inhibitors of HCV NS3-4A protease as potential therapeutic agents against HCV infection

21 January 2018

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BMS-232632, a highly potent human immunodeficiency virus protease inhibitor that can be used in combination with other available antiretroviral agents

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201500103

Preferred conformations of peptides containing tert-leucine, a sterically demanding, lipophilic alpha-amino acid with a quaternary side-chain Cbeta atom

21 January 2018

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Internalization of cationic peptides: the road less (or more?) traveled

21 January 2018

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Cell-penetrating peptides: classes, origin, and current landscape

21 January 2018

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Pathways and mechanisms of endocytic recycling

21 January 2018

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Inhibition of furin/proprotein convertase-catalyzed surface and intracellular processing by small molecules

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201500103

A small-molecule furin inhibitor inhibits cancer cell motility and invasiveness

21 January 2018

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Lessons learned from marketed and investigational prodrugs

21 January 2018

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Development of novel potent orally bioavailable oseltamivir derivatives active against resistant influenza A.

21 January 2018

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17 The kinetics of reversible tight-binding inhibition

21 January 2018

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Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin

21 January 2018

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21 January 2018

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Overview of the CCP4 suite and current developments

21 January 2018

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xdlMAPMAN and xdlDATAMAN - programs for reformatting, analysis and manipulation of biomacromolecular electron-density maps and reflection data sets

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201500103

Version 1.2 of the Crystallography and NMR system

21 January 2018

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Features and development of Coot

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201500103

The Cambridge Structural Database: a quarter of a million crystal structures and rising

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201500103

Validation of protein models from Cα coordinates alone

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201500103

PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500103

Electrostatics of nanosystems: application to microtubules and the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500103

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500103

New substrate analogue furin inhibitors derived from 4-amidinobenzylamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500103

7 January 2021

Cleavage Activation of the Influenza Virus Hemagglutinin and Its Role in Pathogenesis

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500103

7 January 2021

Acylation of octaarginine: Implication to the use of intracellular delivery vectors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500103

7 January 2021

Purification and enzymatic characterization of recombinant prohormone convertase 2: stabilization of activity by 21 kDa 7B2

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500103

7 January 2021

Structural requirements for furin-induced cleavage and activation of Shiga toxin

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500103

7 January 2021