(Q91529794)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

title

The Fungal Histone Acetyl Transferase Gcn5 Controls Virulence of the Human Pathogen Candida albicans through Multiple Pathways (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

Karl Kuchler

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

author name string

Raju Shivarathri

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

Florian Zwolanek

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

Nitesh Kumar Singh

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

Neeraj Chauhan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

publication date

1 July 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

page(s)

9445

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

23 April 2020

DESeq2

object named as

DESeq2 R package

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

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Nosocomial fungal infections: epidemiology, diagnosis, and treatment

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Interaction of Candida Species with the Skin

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Fungal dysbiosis: immunity and interactions at mucosal barriers.

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The burden of invasive infections in neutropenic patients: incidence, outcomes, and use of granulocyte transfusions

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Candida infections, causes, targets, and resistance mechanisms: traditional and alternative antifungal agents

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Bench-to-bedside review: therapeutic management of invasive candidiasis in the intensive care unit

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7 January 2021

Epidemiology and risk factors for invasive candidiasis

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Candida auris: a Review of the Literature.

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Antifungal resistance: current trends and future strategies to combat

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Epidemiology, clinical characteristics, resistance, and treatment of infections by

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The global problem of antifungal resistance: prevalence, mechanisms, and management

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7 January 2021

Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment.

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7 January 2021

Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota

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7 January 2021

Candida albicans morphogenesis and host defence: discriminating invasion from colonization.

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7 January 2021

Targeting chromatin in fungal pathogens as a novel therapeutic strategy: histone modification gets infectious.

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7 January 2021

Novel Agents and Drug Targets to Meet the Challenges of Resistant Fungi

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7 January 2021

The Mechanistic Targets of Antifungal Agents: An Overview

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7 January 2021

The Fungal Cell Wall: Structure, Biosynthesis, and Function.

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7 January 2021

Cell Wall Remodeling Enzymes Modulate Fungal Cell Wall Elasticity and Osmotic Stress Resistance.

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7 January 2021

Dynamic Fungal Cell Wall Architecture in Stress Adaptation and Immune Evasion.

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7 January 2021

Unmasking fungal pathogens by studying MAPK-dependent cell wall regulation in Candida albicans

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7 January 2021

The Role of MAPK Signal Transduction Pathways in the Response to Oxidative Stress in the Fungal Pathogen Candida albicans: Implications in Virulence

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7 January 2021

The MAP kinase signal transduction network in Candida albicans.

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7 January 2021

The MAP kinase Mkc1p is activated under different stress conditions in Candida albicans.

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7 January 2021

The lack of upstream elements of the Cek1 and Hog1 mediated pathways leads to a synthetic lethal phenotype upon osmotic stress in Candida albicans

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7 January 2021

Growth of Candida albicans hyphae

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7 January 2021

Regulatory circuitry governing fungal development, drug resistance, and disease.

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7 January 2021

Environmental sensing and signal transduction pathways regulating morphopathogenic determinants of Candida albicans

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7 January 2021

Candida albicans cell-type switching and functional plasticity in the mammalian host

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7 January 2021

The Paralogous Histone Deacetylases Rpd3 and Rpd31 Play Opposing Roles in Regulating the White-Opaque Switch in the Fungal Pathogen Candida albicans.

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7 January 2021

A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis

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7 January 2021

The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans

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7 January 2021

The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways

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7 January 2021

The histone acetyltransferase Hat1 facilitates DNA damage repair and morphogenesis inCandida albicans

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7 January 2021

Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis.

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7 January 2021

Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy

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7 January 2021

Fungal KATs/KDACs: A New Highway to Better Antifungal Drugs?

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7 January 2021

Chromatin-mediated Candida albicans virulence.

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7 January 2021

A Class 1 Histone Deacetylase with Potential as an Antifungal Target.

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7 January 2021

Histone Deacetylases and Their Inhibition in Candida Species

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7 January 2021

The molecular hallmarks of epigenetic control

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7 January 2021

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7 January 2021

Histone acetyltransferase complexes: one size doesn't fit all

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7 January 2021

The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

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7 January 2021

Gcn5 Modulates the Cellular Response to Oxidative Stress and Histone Deacetylase Inhibition.

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7 January 2021

Distinct roles of the Gcn5 histone acetyltransferase revealed during transient stress-induced reprogramming of the genome

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7 January 2021

Genome-wide characterisation of the Gcn5 histone acetyltransferase in budding yeast during stress adaptation reveals evolutionarily conserved and diverged roles

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7 January 2021

Transcriptomic analysis of the GCN5 gene reveals mechanisms of the epigenetic regulation of virulence and morphogenesis in Ustilago maydis.

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7 January 2021

The UmGcn5 gene encoding histone acetyltransferase from Ustilago maydis is involved in dimorphism and virulence

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7 January 2021

The histone acetyltransferase GcnE (GCN5) plays a central role in the regulation of Aspergillus asexual development

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7 January 2021

Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host

1 reference

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7 January 2021

Gcn5-dependent histone H3 acetylation and gene activity is required for the asexual development and virulence of Beauveria bassiana.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Function and subcellular localization of Gcn5, a histone acetyltransferase in Candida albicans.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

The SAT1 flipper, an optimized tool for gene disruption in Candida albicans

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Functional analysis of the MAPK pathways in fungi

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Fungi sensing environmental stress

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

An extensive circuitry for cell wall regulation in Candida albicans

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Candida albicans cell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Roles of the Candida albicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasis

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Role of Bcr1-activated genes Hwp1 and Hyr1 in Candida albicans oral mucosal biofilms and neutrophil evasion

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Regulation of cell-surface genes and biofilm formation by the C. albicans transcription factor Bcr1p

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

The Candida albicans HYR1 gene, which is activated in response to hyphal development, belongs to a gene family encoding yeast cell wall proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Iron restriction-induced adaptations in the wall proteome of Candida albicans

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Transcript profiling reveals rewiring of iron assimilation gene expression in Candida albicans and C. dubliniensis

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Some biological features of Candida albicans mutants for genes coding fungal proteins containing the CFEM domain

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

A relay network of extracellular heme-binding proteins drives C. albicans iron acquisition from hemoglobin

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

The Iron-Dependent Regulation of the Candida albicans Oxidative Stress Response by the CCAAT-Binding Factor.

1 reference

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7 January 2021

Efg1 Controls caspofungin-induced cell aggregation of Candida albicans through the adhesin Als1.

1 reference

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7 January 2021

Mechanisms of echinocandin antifungal drug resistance

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7 January 2021

Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense

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7 January 2021

Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision

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7 January 2021

The antifungal arsenal: alternative drugs and future targets.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

A role for Gcn5 in replication-coupled nucleosome assembly

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Multi-tasking on chromatin with the SAGA coactivator complexes

1 reference

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7 January 2021

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

1 reference

7 January 2021

Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

The Saccharomyces cerevisiae histone acetyltransferase Gcn5 has a role in the photoreactivation and nucleotide excision repair of UV-induced cyclobutane pyrimidine dimers in the MFA2 gene

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Transcription factors spt3 and spt8 are associated with conidiation, mycelium growth, and pathogenicity in Fusarium graminearum

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

FKS2 and FKS3 genes of opportunistic human pathogen Candida albicans influence echinocandin susceptibility.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Candida albicans and Candida glabrata clinical isolates exhibiting reduced echinocandin susceptibility

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Cell wall perturbation in yeast results in dual phosphorylation of the Slt2/Mpk1 MAP kinase and in an Slt2-mediated increase in FKS2-lacZ expression, glucanase resistance and thermotolerance.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Host-pathogen interactions between the human innate immune system and Candida albicans-understanding and modeling defense and evasion strategies

1 reference

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7 January 2021

SAGA/ADA complex subunit Ada2 is required for Cap1- but not Mrr1-mediated upregulation of the Candida albicans multidrug efflux pump MDR1

1 reference

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7 January 2021

The Candida glabrata Amt1 copper-sensing transcription factor requires Swi/Snf and Gcn5 at a critical step in copper detoxification

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Role of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Multidrug Transporters and Alterations in Sterol Biosynthesis Contribute to Azole Antifungal Resistance in Candida parapsilosis

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Distinct roles of Candida albicans drug resistance transcription factors TAC1, MRR1, and UPC2 in virulence

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

UPC2 is universally essential for azole antifungal resistance in Candida albicans

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

UPC2A is required for high-level azole antifungal resistance in Candida glabrata

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

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https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Adhesins in human fungal pathogens: glue with plenty of stick.

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https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Fungal pathogens-a sweet and sour treat for toll-like receptors

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7 January 2021

Stress adaptation in a pathogenic fungus

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Efg1, a morphogenetic regulator in Candida albicans, is a sequence-specific DNA binding protein

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Efg1-mediated recruitment of NuA4 to promoters is required for hypha-specific Swi/Snf binding and activation in Candida albicans

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Development and regulation of single- and multi-species Candida albicans biofilms

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Adaptive immune responses to Candida albicans infection

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Live Candida albicans suppresses production of reactive oxygen species in phagocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

The Ras/cAMP/PKA signaling pathway and virulence in Candida albicans

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Epigenetic control of oxidative stresses by histone acetyltransferases in Candida albicans

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Histone acetyltransferase encoded by NGG1 is required for morphological conversion and virulence of Candida albicans

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Distinct and redundant roles of the two MYST histone acetyltransferases Esa1 and Sas2 in cell growth and morphogenesis of Candida albicans

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Regulation of white and opaque cell-type formation in Candida albicans by Rtt109 and Hst3

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Extensive functional redundancy in the regulation of Candida albicans drug resistance and morphogenesis by lysine deacetylases Hos2, Hda1, Rpd3 and Rpd31.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Histone deacetylase inhibition as an alternative strategy against invasive aspergillosis.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Molecular Evolution of Antifungal Drug Resistance

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Candida auris: An Emerging Fungal Pathogen

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Activity of MGCD290, a Hos2 histone deacetylase inhibitor, in combination with azole antifungals against opportunistic fungal pathogens.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

In vitro activity of a Hos2 deacetylase inhibitor, MGCD290, in combination with echinocandins against echinocandin-resistant Candida species

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Using combination therapy to thwart drug resistance.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Expression regulation of the yeast PDR5 ATP-binding cassette (ABC) transporter suggests a role in cellular detoxification during the exponential growth phase

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Epigenetic properties of white-opaque switching in Candida albicans are based on a self-sustaining transcriptional feedback loop

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

TopHat: discovering splice junctions with RNA-Seq

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

HTSeq--a Python framework to work with high-throughput sequencing data

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

FungiFun2: a comprehensive online resource for systematic analysis of gene lists from fungal species

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Crystal violet staining to quantify Candida adhesion to epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Functional genomic analysis of Candida glabrata-macrophage interaction: role of chromatin remodeling in virulence.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

The non-receptor tyrosine kinase Tec controls assembly and activity of the noncanonical caspase-8 inflammasome

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections

1 reference

https://api.crossref.org/works/10.1038%2FS41598-019-45817-5

7 January 2021

10.1038/S41598-019-45817-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31263212%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

PubMed publication ID

31263212

1 reference