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The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro
scientific article published on 03 April 2020
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
title
The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro
(English)
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
main subject
SARS-CoV-2
1 reference
based on heuristic
inferred from title
COVID-19
1 reference
based on heuristic
inferred from title
ivermectin
1 reference
based on heuristic
inferred from title
author name string
Leon Caly
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
Julian D Druce
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
Mike G Catton
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
David A Jans
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
Kylie M Wagstaff
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
publication date
3 April 2020
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
published in
Antiviral Research
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
page(s)
104787
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
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Discovering drugs to treat coronavirus disease 2019 (COVID-19)
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PubMed Central
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23 February 2021
The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer
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PubMed Central
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23 February 2021
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Anti-HCV, nucleotide inhibitors, repurposing against COVID-19
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The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus
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Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
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23 February 2021
Safety of high-dose ivermectin: a systematic review and meta-analysis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7129059
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23 February 2021
Safety of oral ivermectin during pregnancy: a systematic review and meta-analysis
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23 February 2021
Multiple-dose versus single-dose ivermectin for Strongyloides stercoralis infection (Strong Treat 1 to 4): a multicentre, open-label, phase 3, randomised controlled superiority trial
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23 February 2021
Lack of efficacy of ivermectin for prevention of a lethal Zika virus infection in a murine system
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23 February 2021
Inhibitors of nuclear transport
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23 February 2021
Ivermectin inhibits DNA polymerase UL42 of pseudorabies virus entrance into the nucleus and proliferation of the virus in vitro and vivo
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23 February 2021
Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import.
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23 February 2021
Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic.
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23 February 2021
The importin α/β-specific inhibitor Ivermectin affects HIF-dependent hypoxia response pathways
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7129059
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23 February 2021
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Nuclear import and export inhibitors alter capsid protein distribution in mammalian cells and reduce Venezuelan Equine Encephalitis Virus replication
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23 February 2021
Nuclear localization of dengue virus (DENV) 1-4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin.
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23 February 2021
Nuclear trafficking of proteins from RNA viruses: potential target for antivirals?
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23 February 2021
Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug
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23 February 2021
Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7129059
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23 February 2021
An AlphaScreen®-based assay for high-throughput screening for specific inhibitors of nuclear import.
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23 February 2021
The pharmacokinetics and interactions of ivermectin in humans--a mini-review
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23 February 2021
Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane
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23 February 2021
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23 February 2021
Localization to the nucleolus is a common feature of coronavirus nucleoproteins, and the protein may disrupt host cell division
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23 February 2021
Measles viruses on throat swabs from measles patients use signaling lymphocytic activation molecule (CDw150) but not CD46 as a cellular receptor
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23 February 2021
The coronavirus infectious bronchitis virus nucleoprotein localizes to the nucleolus.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7129059
retrieved
23 February 2021
Identifiers
DOI
10.1016/J.ANTIVIRAL.2020.104787
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
COVIDWHO ID
covidwho-30819
0 references
Dimensions Publication ID
1126104118
1 reference
stated in
Dimensions COVID-19 publications, datasets and clinical trials
DOI
10.6084/M9.FIGSHARE.11961063
retrieved
28 May 2020
PMCID
7129059
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
PubMed ID
32251768
1 reference
stated in
Europe PubMed Central
PMCID
7129059
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32251768%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 April 2020
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