(Q89865301)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

title

The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1 reference

1 reference

Middle East respiratory syndrome

1 reference

4

Danielle P Porter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

author name string

Calvin J Gordon

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

Egor P Tchesnokov

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

Joy Y Feng

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

Danielle P Porter

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

Matthias Götte

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

language of work or name

English

0 references

publication date

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

number of pages

7

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

volume

295

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

page(s)

4773-4779

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

27 May 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7152756/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Identification of four conserved motifs among the RNA-dependent polymerase encoding elements

1 reference

12 December 2020

Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems

1 reference

12 December 2020

Baculovirus expression system for heterologous multiprotein complexes.

1 reference

12 December 2020

A second, non-canonical RNA-dependent RNA polymerase in SARS Coronavirus

1 reference

12 December 2020

MultiBac: multigene baculovirus-based eukaryotic protein complex production

1 reference

12 December 2020

Delayed chain termination protects the anti-hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase

1 reference

12 December 2020

The respiratory syncytial virus polymerase has multiple RNA synthesis activities at the promoter

1 reference

12 December 2020

Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture

1 reference

12 December 2020

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

1 reference

12 December 2020

Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate

1 reference

12 December 2020

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

1 reference

12 December 2020

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

1 reference

12 December 2020

GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses

1 reference

12 December 2020

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.

1 reference

12 December 2020

Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers.

1 reference

12 December 2020

Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.

1 reference

12 December 2020

Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase.

1 reference

12 December 2020

Recombinant RNA-Dependent RNA Polymerase Complex of Ebola Virus.

1 reference

12 December 2020

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.

1 reference

12 December 2020

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

1 reference

12 December 2020

Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors

1 reference

12 December 2020

Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase

1 reference

12 December 2020

A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics

1 reference

12 December 2020

Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial

1 reference

12 December 2020

Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

1 reference

12 December 2020

Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.AC120.013056

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

27 May 2020

COVIDWHO ID

covidwho-1988

0 references

1125100137

1 reference

Dimensions COVID-19 publications, datasets and clinical trials

DOI

10.6084/M9.FIGSHARE.11961063

28 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32094225%20AND%20SRC:MED&resulttype=core&format=json