(Q91945216)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30808985%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

title

Immunometabolism and natural killer cell responses (English)

1 reference

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25 April 2020

2

1 reference

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25 April 2020

author name string

Katie L O'Brien

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30808985%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

publication date

1 May 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30808985%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

25 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30808985%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30808985%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30808985%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

page(s)

282-290

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30808985%20AND%20SRC:MED&resulttype=core&format=json

Immunometabolism: Cellular Metabolism Turns Immune Regulator

25 April 2020

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Natural killer cell memory in infection, inflammation and cancer

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7 January 2021

T cell- and B cell-independent adaptive immunity mediated by natural killer cells.

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7 January 2021

NK cells regulating T cell responses: mechanisms and outcome

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7 January 2021

Activation-specific metabolic requirements for NK Cell IFN-γ production

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7 January 2021

The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells

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7 January 2021

mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.

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7 January 2021

Metabolic Reprogramming Supports IFN-γ Production by CD56bright NK Cells.

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7 January 2021

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

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7 January 2021

Srebp-controlled glucose metabolism is essential for NK cell functional responses.

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7 January 2021

BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory.

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7 January 2021

Cutting Edge: IL-2-Induced Expression of the Amino Acid Transporters SLC1A5 and CD98 Is a Prerequisite for NKG2D-Mediated Activation of Human NK Cells.

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7 January 2021

Continuous treatment with IL-15 exhausts human NK cells via a metabolic defect.

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7 January 2021

Tissue-resident NK cells differ in their expression profile of the nutrient transporters Glut1, CD98 and CD71

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7 January 2021

Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control

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7 January 2021

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice.

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7 January 2021

The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations.

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7 January 2021

Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase I is essential for cancer cell proliferation independent of β-oxidation.

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7 January 2021

Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation

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7 January 2021

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

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7 January 2021

Maturation of mouse NK cells is a 4-stage developmental program.

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https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

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7 January 2021

Education-dependent activation of glycolysis promotes the cytolytic potency of licensed human natural killer cells

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7 January 2021

Natural Killer Cell Education Is Associated With a Distinct Glycolytic Profile

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7 January 2021

mTORC1 and mTORC2 differentially promote natural killer cell development.

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7 January 2021

The Critical Role of IL-15-PI3K-mTOR Pathway in Natural Killer Cell Effector Functions

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7 January 2021

IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells.

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7 January 2021

Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function

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7 January 2021

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

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7 January 2021

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

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7 January 2021

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

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7 January 2021

Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells

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7 January 2021

The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity

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7 January 2021

Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors

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7 January 2021

AMPKα1: a glucose sensor that controls CD8 T-cell memory

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7 January 2021

mTOR regulates memory CD8 T-cell differentiation

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7 January 2021

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

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7 January 2021

Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function

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7 January 2021

Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals

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7 January 2021

ARID5B regulates metabolic programming in human adaptive NK cells.

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7 January 2021

Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans.

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7 January 2021

Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia

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7 January 2021

Cytokine activation induces human memory-like NK cells

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7 January 2021

Cytokine-induced memory-like natural killer cells

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7 January 2021

Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors.

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7 January 2021

CD16A activation of NK cells promotes NK cell proliferation and memory-like cytotoxicity against cancer cells.

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7 January 2021

Diet-induced obese mice have increased mortality and altered immune responses when infected with influenza virus

1 reference

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7 January 2021

Are natural killer cells protecting the metabolically healthy obese patient?

1 reference

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7 January 2021

Natural killer cells in obesity: impaired function and increased susceptibility to the effects of cigarette smoke

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

NK cells in childhood obesity are activated, metabolically stressed, and functionally deficient.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Termination of the Activating NK Cell Immunological Synapse Is an Active and Regulated Process.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Re-organization of mitochondria at the NK cell immune synapse.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Evidence for immune defects in breast and lung cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Coupling of glucose deprivation with impaired histone H2B monoubiquitination in tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Reversal of tumor acidosis by systemic buffering reactivates NK cells to express IFN-γ and induces NK cell-dependent lymphoma control without other immunotherapies.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Lactate-Mediated Acidification of Tumor Microenvironment Induces Apoptosis of Liver-Resident NK Cells in Colorectal Liver Metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

1 reference

7 January 2021

Elevated plasma levels of transforming growth factor-beta 1 (TGF-beta 1) in patients with advanced breast cancer: association with disease progression

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Canonical TGF-β Signaling Pathway Represses Human NK Cell Metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

27-Hydroxycholesterol Inhibits Sterol Regulatory Element-Binding Protein 1 Activation and Hepatic Lipid Accumulation in Mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Breast cancer and (25R)-26-hydroxycholesterol

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

The immune regulation in cancer by the amino acid metabolizing enzymes ARG and IDO.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Single cell analysis of kynurenine and System L amino acid transport in T cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Antibody-modified T cells: CARs take the front seat for hematologic malignancies

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

NK cell-based immunotherapy for malignant diseases

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Hopefully devoted to Q: targeting glutamine addiction in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Metabolic Imaging of Glutamine in Cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of 18F-(2S,4R )-4-Fluoroglutamine.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

PET imaging of glutaminolysis in tumors by 18F-(2S,4R)4-fluoroglutamine.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Repression of GSK3 restores NK cell cytotoxicity in AML patients

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

GSK 3 inhibition drives maturation of NK cells and enhances their antitumor activity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells

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https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

NK-92: an 'off-the-shelf therapeutic' for adoptive natural killer cell-based cancer immunotherapy

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Metabolic maintenance of cell asymmetry following division in activated T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

1 reference

https://api.crossref.org/works/10.1038%2FS41577-019-0139-2

7 January 2021

10.1038/S41577-019-0139-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30808985%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

1 reference