(Q104527850)

English

Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification

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Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification (English)

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1 reference

based on heuristic

inferred from title

Non-structural protein 10 [SARS CoV-2]

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based on heuristic

inferred from abstract

Non-structural protein 14 [SARS-CoV-2]

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based on heuristic

inferred from abstract

Abimael Cruz Migoni

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ORCID Public Data File 2021

Christopher J. Schofield

9

object named as

Christopher J. Schofield

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author name string

Hannah T. Baddock

1

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Sanja Brolih

2

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Yuliana Yosaatmadja

3

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Malitha Ratnaweera

4

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Marcin Bielinski

5

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Lonnie P. Swift

6

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Abimael Cruz-Migoni

7

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Garrett M. Morris

8

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Opher Gileadi

10

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Peter J. McHugh

11

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publication date

13 August 2020

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Human Coronavirus: Host-Pathogen Interaction

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

SARS-CoV ORF1b-encoded nonstructural proteins 12-16: replicative enzymes as antiviral targets.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Discovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesis

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

In vitro reconstitution of SARS-coronavirus mRNA cap methylation

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Nidovirus RNA polymerases: Complex enzymes handling exceptional RNA genomes

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Processing ribonucleotides incorporated during eukaryotic DNA replication.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

mA: Widespread regulatory control in virus replication

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Epitranscriptomic marks: Emerging modulators of RNA virus gene expression

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Use of aurintricarboxylic acid as an inhibitor of nucleases during nucleic acid isolation

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1-XPF.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

In-Silico docking of HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Ebselen, a useful tool for understanding cellular redox biology and a promising drug candidate for use in human diseases

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Structure of Mpro from COVID-19 virus and discovery of its inhibitors

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Density functional theory study of the attack of ebselen on a zinc-finger model

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II).

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Interaction of selenium compounds with zinc finger proteins involved in DNA repair

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Ebselen, a selenium-containing redox drug, releases zinc from metallothionein

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

High-throughput production of human proteins for crystallization: the SGC experience.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

Site-directed mutagenesis by inverse PCR.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold To Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII.

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

3-Hydroxypyrimidine-2,4-diones as an inhibitor scaffold of HIV integrase

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

NIH Image to ImageJ: 25 years of image analysis

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

1 reference

https://api.crossref.org/works/10.1101/2020.08.13.248211

27 December 2020

The synthesis of (±)-xanthorrhoein

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3-Hydroxy- and 3-alkoxy-2-sulfanylquinazolin-4(3H)-ones: synthesis and reactions with alkylating and acylating agents

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Identifiers

10.1101/2020.08.13.248211

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