Wikidata

(Q105219586)

English

Rapamycin (TN)

group of stereoisomers with the chemical formula C₅₁H₇₉NO₁₃

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Statements

mass
913.555141588 dalton
1 reference
based on heuristic
inferred from SMILES
chemical formula
C₅₁H₇₉NO₁₃
0 references
canonical SMILES
O=C1OC(CC(=O)C(C=C(C)C(O)C(OC)C(=O)C(C)CC(C=CC=CC=C(C)C(OC)CC2OC(O)(C(=O)C(=O)N3CCCCC13)C(C)CC2)C)C)C(C)CC4CCC(O)C(OC)C4
0 references
isomeric SMILES
CO[C@H]1CC2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCCC2C(=O)OC([C@H](C)C[C@@H]2CC[C@@H](O)[C@H](OC)C2)CC(=O)[C@H](C)/C=C(\C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C\C=C\C=C\1C
0 references
found in taxon
Streptomyces hygroscopicus
13 references
stated in
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase
stated in
Effects of dissolved oxygen level on rapamycin production by pellet-form of Streptomyces hygroscopicus
stated in
Comparative metabolic profiling-based improvement of rapamycin production by Streptomyces hygroscopicus
stated in
Incorporation of acetate, propionate, and methionine into rapamycin by Streptomyces hygroscopicus
stated in
A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253.
stated in
Phosphate, ammonium, magnesium and iron nutrition of Streptomyces hygroscopicus with respect to rapamycin biosynthesis
stated in
Effect of immobilisation on production of rapamycin by Streptomyces hygroscopicus.
stated in
Carbon source nutrition of rapamycin biosynthesis in Streptomyces hygroscopicus
stated in
The pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin--nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus.
stated in
A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain
stated in
Production of rapamycin in Streptomyces hygroscopicus from glycerol-based media optimized by systemic methodology
stated in
Studies on process optimization methods for rapamycin production using Streptomyces hygroscopicus ATCC 29253.
stated in
Effect of nitrogen source on biosynthesis of rapamycin by Streptomyces hygroscopicus

Identifiers

 
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