(Q115250625)

1

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Abbas El Sahili

2

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ZhenZhen Zhang

3

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Ming Wei Chen

4

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Chong Wai Liew

5

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Julien Lescar

6

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Subhash G. Vasudevan

7

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Dahai Luo

Steady-state NTPase activity of Dengue virus NS3: number of catalytic sites, nucleotide specificity and activation by ssRNA.

8

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publication date

27 January 2020

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cites work

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Targets for antiviral therapy of hepatitis C.

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Towards antiviral therapies for treating dengue virus infections.

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus.

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

NADH-coupled microplate photometric assay for kinetic studies of ATP-hydrolyzing enzymes with low and high specific activities

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Features and development of Coot

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Zika Virus Infection in Pregnant Women in Rio de Janeiro — Preliminary Report

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Flexibility between the protease and helicase domains of the dengue virus NS3 protein conferred by the linker region and its functional implications

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Towards automated crystallographic structure refinement with phenix.refine

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Structural biology of dengue virus enzymes: towards rational design of therapeutics

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 A

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Preventing Zika Virus Infections in Pregnant Women: An Urgent Public Health Priority

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Integration, scaling, space-group assignment and post-refinement

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Product release is rate-limiting for catalytic processing by the Dengue virus protease

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Protein structural alignment for detection of maximally conserved regions

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Structural characterization of the linked NS2B-NS3 protease of Zika virus

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

The flavivirus NS2B-NS3 protease-helicase as a target for antiviral drug development

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Dengue Virus NS2B/NS3 Protease Inhibitors Exploiting the Prime Side

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

NMR analysis of a novel enzymatically active unlinked dengue NS2B-NS3 protease complex

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Binding of low molecular weight inhibitors promotes large conformational changes in the dengue virus NS2B-NS3 protease: fold analysis by pseudocontact shifts

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Cotranslational membrane insertion of the serine proteinase precursor NS2B-NS3(Pro) of dengue virus type 2 is required for efficient in vitro processing and is mediated through the hydrophobic regions of NS2B.

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries.

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B-NS3 protease

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Binding mode of the activity-modulating C-terminal segment of NS2B to NS3 in the dengue virus NS2B-NS3 protease

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Structure of the NS2B-NS3 protease from Zika virus after self-cleavage

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Current Status of Dengue Therapeutics Research and Development

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

NMR Analysis of the Dynamic Exchange of the NS2B Cofactor between Open and Closed Conformations of the West Nile Virus NS2B-NS3 Protease

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Crystal Structure of a Novel Conformational State of the Flavivirus NS3 Protein: Implications for Polyprotein Processing and Viral Replication

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Serotype-Specific Structural Differences in the Protease-Cofactor Complexes of the Dengue Virus Family

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Development and characterization of new peptidomimetic inhibitors of the West Nile virus NS2B-NS3 protease

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Coot: model-building tools for molecular graphics

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors.

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Flavivirus genome organization, expression, and replication

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Improvements in the analysis of domain motions in proteins from conformational change: DynDom version 1.50

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Structural evidence for regulation and specificity of flaviviral proteases and evolution of theFlaviviridaefold

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Crystal Structure of the NS3 Protease-Helicase from Dengue Virus

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

How good are my data and what is the resolution?

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Molecular biology of flaviviruses

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

The RNA helicase, nucleotide 5'-triphosphatase, and RNA 5'-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a functional Walker B motif in the helicase catalytic core.

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Overview of the CCP4 suite and current developments

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

A graphical user interface to the CCP4 program suite

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Crystal structure of unlinked NS2B-NS3 protease from Zika virus

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

An introduction to data reduction: space-group determination, scaling and intensity statistics

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089

Evolutionarily conserved protein sequences of influenza a viruses, avian and human, as vaccine targets

21 November 2022

1 reference

https://api.crossref.org/works/10.1101/2020.01.27.907089