(Q14912280)

English

CHEK2

protein-coding gene in the species Homo sapiens

CDS1
CHK2
HuCds1
LFS2
PP1425
RAD53
hCds1
checkpoint kinase 2

In more languages

Statements

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

protein-coding gene

1 reference

Ensembl Release 87

Ensembl gene ID

ENSG00000183765

Protein CHEK2 PDB 1gxc.png
961 × 735; 375 KB

0 references

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

checkpoint kinase 2

1 reference

6 July 2017

UniProt protein ID

Serine/threonine-protein kinase Chk2

1 reference

UniProt protein ID

21 March 2016

language of work or name

genetic association

esophagus squamous cell carcinoma

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_3748&ncbiId=11200

http://www.genome.gov/gwastudies/index.cfm?gene=CHEK2

Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

25 May 2020

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_1324&ncbiId=11200

http://www.genome.gov/gwastudies/index.cfm?gene=CHEK2

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

25 May 2020

breast carcinoma

1 reference

Open Targets Platform

24 August 2023

https://platform.opentargets.org/evidence/ENSG00000183765/EFO_0000305

based on heuristic

inferred from an Open Targets association score over 0.7

prostate carcinoma

1 reference

Open Targets Platform

24 August 2023

https://platform.opentargets.org/evidence/ENSG00000183765/EFO_0001663

based on heuristic

inferred from an Open Targets association score over 0.7

urogenital neoplasm

1 reference

Open Targets Platform

24 August 2023

https://platform.opentargets.org/evidence/ENSG00000183765/EFO_0003869

based on heuristic

inferred from an Open Targets association score over 0.7

human chromosome 22

genomic assembly

genome assembly GRCh38

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

strand orientation

genomic assembly

genome assembly GRCh38

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

28687743

human chromosome 22

genomic assembly

genome assembly GRCh38

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

29083731

human chromosome 22

genomic assembly

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

28742422

human chromosome 22

genomic assembly

genome assembly GRCh38

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

29138410

human chromosome 22

genomic assembly

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

cytogenetic location

22q12.1

1 reference

15 May 2022

38289

1 reference

15 May 2022

Gene Atlas image

PBB GE CHEK2 210416 s at fs.png
732 × 530; 12 KB

0 references

1 reference

HomoloGene build68

38289

1 reference

HomoloGene build68

38289

Saccharomyces cerevisiae S288c

1 reference

HomoloGene build68

38289

Caenorhabditis elegans

1 reference

HomoloGene build68

38289

1 reference

HomoloGene build68

38289

Caenorhabditis elegans

1 reference

HomoloGene build68

38289

Drosophila melanogaster

1 reference

HomoloGene build68

38289

1

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000183765

2

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000183765

secondary oocyte

3

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000183765

4

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000183765

ganglionic eminence

5

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000183765

stromal cell of endometrium

6

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000183765

right lobe of liver

7

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000183765

8

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000183765

canal of the cervix

9

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000183765

Achilles tendon

10

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000183765

http://identifiers.org/ncbigene/11200

1 reference

Identifiers.org

http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069

Identifiers

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

10 April 2022

1 reference

10 April 2022

1 reference

10 April 2022

1 reference

10 April 2022

1 reference

10 April 2022

1 reference

10 April 2022

1 reference

10 April 2022

1 reference

15 May 2022

0 references

Encyclopædia Britannica Online ID

subject named as

CHEK2

0 references

Ensembl gene ID

ENSG00000183765

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

Ensembl transcript ID

ENST00000491919

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000348295

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000382580

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000398017

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000402731

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000403642

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000404276

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000405598

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000416671

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000417588

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000425190

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000433028

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000433728

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000434810

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000439200

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000439346

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000448511

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000454252

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000456369

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000464581

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000472807

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000650233

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000648295

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000650281

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

ENST00000649563

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000183765

0 references

HGNC gene symbol

1 reference

15 May 2022

1 reference

15 May 2022

Microsoft Academic ID

0 references

0 references

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

based on heuristic

inferred by common HGNC mappings on source and on Wikidata

15 June 2023

Sitelinks

Wikipedia(7 entries)

bswiki CHEK2
cywiki CHEK2
enwiki CHEK2
eswiki CHEK2
jawiki CHEK2
plwiki CHEK2
ukwiki CHEK2

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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