(Q21131205)

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Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics

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Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics (English)

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based on heuristic

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lessons learned

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based on heuristic

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Luca Pastorelli

object named as

Luca Pastorelli

1

author given names

Luca

author last names

Pastorelli

1 reference

16 August 2022

author name string

Carlo De Salvo

2

author given names

Carlo

author last names

De Salvo

1 reference

16 August 2022

Joseph R Mercado

3

author given names

Joseph R

author last names

Mercado

1 reference

16 August 2022

Maurizio Vecchi

4

author given names

Maurizio

author last names

Vecchi

1 reference

16 August 2022

Theresa T Pizarro

5

author given names

Theresa T

author last names

Pizarro

1 reference

16 August 2022

language of work or name

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publication date

2013

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Frontiers in Immunology

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4

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280

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Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

1 reference

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19 March 2017

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

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19 March 2017

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

1 reference

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19 March 2017

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

1 reference

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19 March 2017

Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis

1 reference

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19 March 2017

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

1 reference

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19 March 2017

Toll-like receptor signalling

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19 March 2017

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

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19 March 2017

Reduced heparan sulfate accumulation in enterocytes contributes to protein-losing enteropathy in a congenital disorder of glycosylation

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19 March 2017

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

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19 March 2017

Identification of a novel human homolog of the Drosophila dlg, P-dlg, specifically expressed in the gland tissues and interacting with p55

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19 March 2017

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

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19 March 2017

Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

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19 March 2017

Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function

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19 March 2017

Genetic variation in myosin IXB is associated with ulcerative colitis

1 reference

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19 March 2017

Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect

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19 March 2017

Sargramostim for active Crohn's disease

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19 March 2017

Genetic variation in DLG5 is associated with inflammatory bowel disease

1 reference

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19 March 2017

Functional variants of OCTN cation transporter genes are associated with Crohn disease

1 reference

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19 March 2017

Defensins: antimicrobial peptides of innate immunity

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19 March 2017

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

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19 March 2017

Myosin-IXb is a single-headed and processive motor

1 reference

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19 March 2017

Molecular and functional characterization of organic cation/carnitine transporter family in mice

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19 March 2017

Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor

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19 March 2017

Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease

1 reference

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19 March 2017

Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease

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19 March 2017

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

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7 April 2017

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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7 April 2017

Autophagy as a regulated pathway of cellular degradation

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7 April 2017

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

1 reference

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7 April 2017

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

1 reference

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7 April 2017

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

1 reference

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7 April 2017

Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

1 reference

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7 April 2017

An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

1 reference

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7 April 2017

Innate immunity

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7 April 2017

Increased expression of interleukin 17 in inflammatory bowel disease

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7 April 2017

Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis

1 reference

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12 September 2017

Probiotic bacteria regulate intestinal epithelial permeability in experimental ileitis by a TNF-dependent mechanism

1 reference

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12 September 2017

A randomized, double-blind study of larazotide acetate to prevent the activation of celiac disease during gluten challenge

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12 September 2017

The epithelia-specific membrane trafficking factor AP-1B controls gut immune homeostasis in mice.

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12 September 2017

SAMP1/YitFc mouse strain: a spontaneous model of Crohn's disease-like ileitis

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12 September 2017

p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice

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12 September 2017

Commensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine

1 reference

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12 September 2017

Probiotics promote gut health through stimulation of epithelial innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Mechanisms of tight junction dysregulation in the SAMP1/YitFc model of Crohn's disease-like ileitis

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12 September 2017

Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency

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12 September 2017

Genetic variants of Wnt transcription factor TCF-4 (TCF7L2) putative promoter region are associated with small intestinal Crohn's disease

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12 September 2017

Differential susceptibility of P-glycoprotein deficient mice to colitis induction by environmental insults

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12 September 2017

Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.

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12 September 2017

Mechanisms of probiotic action: Implications for therapeutic applications in inflammatory bowel diseases

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12 September 2017

Intestinal deletion of Pofut1 in the mouse inactivates notch signaling and causes enterocolitis.

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12 September 2017

Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis

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12 September 2017

Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel disease

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12 September 2017

Heparan sulfate and syndecan-1 are essential in maintaining murine and human intestinal epithelial barrier function

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12 September 2017

JAM-A regulates permeability and inflammation in the intestine in vivo

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12 September 2017

Deletion of TLR5 results in spontaneous colitis in mice

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12 September 2017

Review article: the role of butyrate on colonic function.

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12 September 2017

The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: a proof of concept study

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12 September 2017

Meta-analysis: The utility and safety of heparin in the treatment of active ulcerative colitis.

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12 September 2017

New diseases derived or associated with the tight junction.

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12 September 2017

Probiotics in experimental and human inflammatory bowel disease: discussion points

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12 September 2017

Genetics of the innate immune response in inflammatory bowel disease

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12 September 2017

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease

1 reference

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12 September 2017

Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

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12 September 2017

Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon

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12 September 2017

The primary defect in experimental ileitis originates from a nonhematopoietic source

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12 September 2017

Slipping the barrier: how variants in CARD15 could alter permeability of the intestinal wall and population health

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12 September 2017

Biologic therapy for inflammatory bowel disease.

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12 September 2017

Systematic review of the effects of n-3 fatty acids in inflammatory bowel disease

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12 September 2017

Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation?

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12 September 2017

Genetics of Crohn disease, an archetypal inflammatory barrier disease

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12 September 2017

Effect of lactobacillus on the gut microflora and barrier function of the rats with abdominal infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Altered epithelial cell lineage allocation and global expansion of the crypt epithelial stem cell population are associated with ileitis in SAMP1/YitFc mice

1 reference

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12 September 2017

Defensin deficiency, intestinal microbes, and the clinical phenotypes of Crohn's disease

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12 September 2017

Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient mice

1 reference

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12 September 2017

Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Bacterial flagellin is a dominant antigen in Crohn disease.

1 reference

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12 September 2017

MDR1 Ala893 polymorphism is associated with inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Rationale for probiotic and antibiotic treatment strategies in inflammatory bowel diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Raft ceramide in molecular medicine

1 reference

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12 September 2017

Identification of a quantitative trait locus for ileitis in a spontaneous mouse model of Crohn's disease: SAMP1/YitFc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Crohn's disease and the NOD2 gene: a role for paneth cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Role of mucins in inflammatory bowel disease: important lessons from experimental models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Human lactoferrin: a novel therapeutic with broad spectrum potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Review: the role of omega 3 fatty acids in intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Mucin secretion is modulated by luminal factors in the isolated vascularly perfused rat colon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Kallistatin, a novel human tissue kallikrein inhibitor: levels in body fluids, blood cells, and tissues in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Lactobacillus acidophilus LA 1 binds to cultured human intestinal cell lines and inhibits cell attachment and cell invasion by enterovirulent bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Colonic mucin synthesis is increased by sodium butyrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Colonic epithelium is diffusely abnormal in ulcerative colitis and colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

12 September 2017

Oestradiol decreases colonic permeability through oestrogen receptor beta-mediated up-regulation of occludin and junctional adhesion molecule-A in epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Cathelicidin stimulates colonic mucus synthesis by up-regulating MUC1 and MUC2 expression through a mitogen-activated protein kinase pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

The short chain fatty acid, butyrate, stimulates MUC2 mucin production in the human colon cancer cell line, LS174T.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Molecular mechanisms underlying the probiotic effects of Escherichia coli Nissle 1917 involve ZO-2 and PKCzeta redistribution resulting in tight junction and epithelial barrier repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Escherichia coli strain Nissle 1917 ameliorates experimental colitis via toll-like receptor 2- and toll-like receptor 4-dependent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Expression of Toll-like receptor 9 and response to bacterial CpG oligodeoxynucleotides in human intestinal epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Effects of fermentation products of pro- and prebiotics on trans-epithelial electrical resistance in an in vitro model of the colon.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Involvement of Galphai2 in the maintenance and biogenesis of epithelial cell tight junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Effect of short-chain fatty acids on paracellular permeability in Caco-2 intestinal epithelium model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Molecular and cellular aspects of the secretory immunoglobulin system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Kinin formation: mechanisms and role in inflammatory disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

A conserved signaling pathway: the Drosophila toll-dorsal pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

27 September 2017

MAGI2 genetic variation and inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

IL-17 produced by Paneth cells drives TNF-induced shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(-/-) mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

Associations with tight junction genes PARD3 and MAGI2 in Dutch patients point to a common barrier defect for coeliac disease and ulcerative colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

Exogenous sphingomyelinase causes impaired intestinal epithelial barrier function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

Polyunsaturated fatty acids reduce non-receptor-mediated transcellular permeation of protein across a model of intestinal epithelium in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

Omega-3 fatty acids and low carbohydrate diet for maintenance of remission in Crohn's disease. A randomized controlled multicenter trial. Study Group Members (German Crohn's Disease Study Group).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

Disruption of sulphated glycosaminoglycans in intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

A working hypothesis for the etiology and pathogenesis of nonspecific inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

Drosophila Toll and IL-1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

Fish oil fatty acid supplementation in active ulcerative colitis: a double-blind, placebo-controlled, crossover study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

30 May 2018

A gender gap in autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

19 June 2018

Interleukin-1β (IL-1β) promotes susceptibility of Toll-like receptor 5 (TLR5) deficient mice to colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Probiotic mixture VSL#3 protects the epithelial barrier by maintaining tight junction protein expression and preventing apoptosis in a murine model of colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Oral, colonic-release low-molecular-weight heparin: an initial open study of Parnaparin-MMX for the treatment of mild-to-moderate left-sided ulcerative colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Association of DLG5 variants with gluten-sensitive enteropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Efficacy of intracolonic administration of low-molecular-weight heparin CB-01-05, compared to other low-molecular-weight heparins and unfractionated heparin, in experimentally induced colitis in rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

The Crohn's disease susceptibility gene DLG5 as a member of the CARD interaction network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Gut immune stimulation by non pathogenic Gram(+) and Gram(-) bacteria. Comparison with a probiotic strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Bugging of the intestinal mucosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Loss of the tight junction protein ZO-1 in dextran sulfate sodium induced colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Epithelial heparin delivery via microspheres mitigates experimental colitis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

DLG5 R30Q variant is a female-specific protective factor in pediatric onset Crohn's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Protection against dextran sodium sulfate-induced colitis by dehydroepiandrosterone and 7alpha-hydroxy-dehydroepiandrosterone in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Cdcs1, a Major Colitogenic Locus in Mice, Regulates Innate and Adaptive Immune Response to Enteric Bacterial Antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Kallikrein–kinin system in inflammatory bowel diseases: Intestinal involvement and correlation with the degree of tissue inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Trial of trefoil factor 3 enemas, in combination with oral 5-aminosalicylic acid, for the treatment of mild-to-moderate left-sided ulcerative colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Epithelial transport and barrier function in occludin-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Epithelial dysfunction associated with the development of colitis in conventionally housed mdr1a-/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

The BsmI vitamin D receptor gene polymorphism is associated with ulcerative colitis in Jewish Ashkenazi patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor alpha antibody treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Colony-Stimulating Factor-1 Promotes Clonogenic Growth of Normal Murine Colonic Crypt Epithelial Cells In Vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Crohn's disease is associated with a toll-like receptor-9 polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Ceramide selectively displaces cholesterol from ordered lipid domains (rafts): implications for lipid raft structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Beneficial effects of estrogen treatment in the HLA-B27 transgenic rat model of inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: results of a multicentre trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Effect of gamma-linolenic acid or docosahexaenoic acid on tight junction permeability in intestinal monolayer cells and their mechanism by protein kinase C activation and/or eicosanoid formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Effect of granulocyte-macrophage colony stimulating factor on bacterial translocation after experimental obstructive jaundice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Effect of butyrate on paracellular permeability in rat distal colonic mucosa ex vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Genetic analysis of susceptibility to dextran sulfate sodium-induced colitis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3775315

29 November 2018

Epithelial NEMO links innate immunity to chronic intestinal inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal intestinal permeability predicts relapse in inactive Crohn disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in mucosal content of colonic glycoconjugates in inflammatory bowel disease defined by monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal permeability test as a predictor of clinical course in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probiotics and inflammatory bowel diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical trial: oral colon-release parnaparin sodium tablets (CB-01-05 MMX) for active left-sided ulcerative colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congenital enterocyte heparan sulphate deficiency with massive albumin loss, secretory diarrhoea, and malnutrition

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of butyrate on intestinal barrier function in a Caco-2 cell monolayer model of intestinal barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased intestinal permeability and NOD2 variants in familial and sporadic Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kallikrein-kinin system activation in Crohn's disease: differences in intestinal and systemic markers

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetics of inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous, heritable colitis in a new substrain of C3H/HeJ mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gender and disease activity influence health-related quality of life in inflammatory bowel diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Megaintestine in claudin-15-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of ulcerative colitis with rare VNTR alleles of the human intestinal mucin gene, MUC3

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gi2 alpha protein deficiency: a model of inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of left-sided ulcerative colitis with butyrate enemas: a controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperresponsiveness of the Mucosal Barrier in Crohnʼs Disease Is Not Tumor Necrosis Factor-Dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial cell-intrinsic Notch signaling plays an essential role in the maintenance of gut immune homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apical junction complex protein expression in the canine colon: differential expression of claudin-2 in the colonic mucosa in dogs with idiopathic colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential role for the common cystic fibrosis ΔF508 mutation in Crohnʼs disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylcholine and lysophosphatidylcholine in intestinal mucus of ulcerative colitis patients. A quantitative approach by nanoElectrospray-tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hapten-induced model of chronic inflammation and ulceration in the rat colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/24062746

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FIMMU.2013.00280

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

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