(Q21131398)

English

The cholesterol-dependent cytolysin signature motif: a critical element in the allosteric pathway that couples membrane binding to pore assembly

scientific article

The Cholesterol-Dependent Cytolysin Signature Motif: A Critical Element in the Allosteric Pathway that Couples Membrane Binding to Pore Assembly

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scholarly article

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The cholesterol-dependent cytolysin signature motif: a critical element in the allosteric pathway that couples membrane binding to pore assembly (English)

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author name string

Kelley J Dowd

1

author given names

Kelley J

author last names

Dowd

1 reference

PubMed publication ID

16 August 2022

Allison J Farrand

2

author given names

Allison J

author last names

Farrand

1 reference

PubMed publication ID

16 August 2022

Rodney K Tweten

3

author given names

Rodney K

author last names

Tweten

1 reference

PubMed publication ID

16 August 2022

language of work or name

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publication date

2012

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8

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7

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e1002787

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copyright license

Creative Commons Attribution 4.0 International

5 July 2012

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April 2022 Public Data File from Crossref

copyright status

0 references

Characterization of a streptococcal cholesterol-dependent cytolysin with a lewis y and b specific lectin domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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Essential role of membrane-attack protein in malarial transmission to mosquito host

1 reference

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Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement

1 reference

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1 reference

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Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis

1 reference

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Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense

1 reference

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1 reference

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Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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VMD: visual molecular dynamics

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

12 September 2017

Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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Functional and phylogenetic characterization of Vaginolysin, the human-specific cytolysin from Gardnerella vaginalis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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The Bax pore in liposomes, Biophysics

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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1 reference

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Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit beta-strand alignment.

1 reference

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Assembly and topography of the prepore complex in cholesterol-dependent cytolysins

1 reference

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1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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Pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae, does not require a thiol group for in vitro activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390400

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002787

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1 reference

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002787

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002787

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002787

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002787

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1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002787

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22792065

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based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22792065

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1 reference

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1 reference

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1 reference

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inferred from PubMed ID database lookup

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10.1371/JOURNAL.PPAT.1002787

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