(Q21981550)

http://www.ebi.ac.uk/interpro/protein/Q91XB0

Ribonuclease H-like superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q91XB0

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

Exonuclease, RNase T/DNA polymerase III family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

protein homodimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

adenyl deoxyribonucleotide binding

1 reference

14 February 2019

The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

single-stranded DNA binding

exodeoxyribonuclease III activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

3'-5'-exodeoxyribonuclease activity

1 reference

21 June 2018

Excision of 3' termini by the Trex1 and TREX2 3'-->5' exonucleases. Characterization of the recombinant proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91XB0&geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

MutLalpha complex binding

1 reference

31 January 2018

ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91XB0&geneProductId=UniProtKB:Q91XB0

MutSalpha complex binding

ISO

1 reference

31 January 2018

ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91XB0&geneProductId=UniProtKB:Q91XB0

3'-5' exonuclease activity

ISO

magnesium ion binding

1 reference

14 February 2019

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

3'-5' exonuclease activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91XB0&geneProductId=UniProtKB:Q91XB0

endoplasmic reticulum membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91XB0&geneProductId=UniProtKB:Q91XB0

endoplasmic reticulum

1 reference

10 September 2018

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91XB0&geneProductId=UniProtKB:Q91XB0

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

endoplasmic reticulum

3 references

14 February 2019

14 February 2019

Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Trex1 prevents cell-intrinsic initiation of autoimmunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Immunostimulatory Endogenous Nucleic Acids Drive the Lesional Inflammation in Cutaneous Lupus Erythematosus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

oligosaccharyltransferase complex

1 reference

14 February 2019

Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

nuclear replication fork

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

cellular response to interferon-beta

biological process

1 reference

14 February 2019

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

nucleic acid phosphodiester bond hydrolysis

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Excision of 3' termini by the Trex1 and TREX2 3'-->5' exonucleases. Characterization of the recombinant proteins

DNA metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

blood vessel development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

adaptive immune response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

organ or tissue specific immune response

1 reference

14 February 2019

The exonuclease Trex1 restrains macrophage proinflammatory activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

activation of immune response

1 reference

14 February 2019

Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

macrophage activation involved in immune response

1 reference

14 February 2019

The exonuclease Trex1 restrains macrophage proinflammatory activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

lymphoid progenitor cell differentiation

1 reference

14 February 2019

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

immune response in brain or nervous system

1 reference

14 February 2019

The exonuclease Trex1 restrains macrophage proinflammatory activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

inflammatory response to antigenic stimulus

1 reference

14 February 2019

The exonuclease Trex1 restrains macrophage proinflammatory activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

T cell antigen processing and presentation

1 reference

14 February 2019

The exonuclease Trex1 restrains macrophage proinflammatory activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of immunoglobulin production

1 reference

14 February 2019

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

atrial cardiac muscle tissue development

1 reference

14 February 2019

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

generation of precursor metabolites and energy

1 reference

14 February 2019

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of glycolytic process

1 reference

14 February 2019

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

Filamin-A regulates neutrophil uropod retraction through RhoA during chemotaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

DNA catabolic process

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Early onset of autoimmune disease by the retroviral integrase inhibitor raltegravir.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Trex1 prevents cell-intrinsic initiation of autoimmunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

inflammatory response

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Immunostimulatory Endogenous Nucleic Acids Drive the Lesional Inflammation in Cutaneous Lupus Erythematosus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

cellular response to DNA damage stimulus

1 reference

14 February 2019

Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

determination of adult lifespan

3 references

14 February 2019

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

Immunostimulatory Endogenous Nucleic Acids Drive the Lesional Inflammation in Cutaneous Lupus Erythematosus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of fatty acid metabolic process

1 reference

14 February 2019

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of cellular metabolic process

transposition, RNA-mediated

1 reference

14 February 2019

Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of type I interferon production

3 references

14 February 2019

IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

14 February 2019

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

1 reference

14 February 2019

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

interferon-alpha production

1 reference

14 February 2019

The exonuclease Trex1 restrains macrophage proinflammatory activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of tumor necrosis factor production

1 reference

14 February 2019

The exonuclease Trex1 restrains macrophage proinflammatory activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

cellular response to oxidative stress

1 reference

14 February 2019

Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

cellular response to reactive oxygen species

1 reference

14 February 2019

Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage

cellular response to UV

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

CD86 biosynthetic process

1 reference

14 February 2019

The exonuclease Trex1 restrains macrophage proinflammatory activation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

The exonuclease Trex1 restrains macrophage proinflammatory activation.

apoptotic cell clearance

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of cellular respiration

1 reference

14 February 2019

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

innate immune response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of innate immune response

establishment of protein localization

1 reference

14 February 2019

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of lipid biosynthetic process

1 reference

14 February 2019

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of inflammatory response

1 reference

14 February 2019

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of catalytic activity

1 reference

14 February 2019

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation

protein stabilization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of T cell activation

1 reference

14 February 2019

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

type I interferon signaling pathway

1 reference

14 February 2019

Immunostimulatory Endogenous Nucleic Acids Drive the Lesional Inflammation in Cutaneous Lupus Erythematosus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

negative regulation of type I interferon-mediated signaling pathway

1 reference

14 February 2019

Trex1 prevents cell-intrinsic initiation of autoimmunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of protein complex stability

1 reference

14 February 2019

Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

cellular response to organic substance

1 reference

14 February 2019

Immunostimulatory Endogenous Nucleic Acids Drive the Lesional Inflammation in Cutaneous Lupus Erythematosus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

cellular response to type I interferon

1 reference

14 February 2019

Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

cellular response to gamma radiation

1 reference

14 February 2019

Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

cellular response to hydroxyurea

1 reference

14 February 2019

Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

immune complex formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

DNA synthesis involved in UV-damage excision repair

1 reference

14 February 2019

Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

regulation of lysosome organization

1 reference

14 February 2019

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91XB0

Exonuclease, RNase T/DNA polymerase III

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q91XB0

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016