(Q24294605)

GOA release 2020-03-11

author

Antony W. Oliver

1

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Laurence Pearl

8

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author name string

Angela Paul

2

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Katherine J Boxall

3

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S Elaine Barrie

4

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G Wynne Aherne

5

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Michelle D Garrett

6

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Sibylle Mittnacht

on focus list of Wikimedia project

7

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language of work or name

English

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publication date

12 July 2006

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published in

The EMBO Journal

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volume

25

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issue

13

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page(s)

3179-90

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ScienceSource

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cites work

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

1 reference

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Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

19 March 2017

1 reference

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Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

19 March 2017

1 reference

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The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Phosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Likelihood-enhanced fast translation functions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Coot: model-building tools for molecular graphics

19 March 2017

1 reference

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The CCP4 suite: programs for protein crystallography

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Protein structure comparison by alignment of distance matrices

19 March 2017

1 reference

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LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

19 March 2017

1 reference

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Crystal structures of the phosphorylated and unphosphorylated kinase domains of the Cdc42-associated tyrosine kinase ACK1

19 March 2017

1 reference

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Checking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressor

19 March 2017

1 reference

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Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain

19 March 2017

1 reference

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Targeting chk2 kinase: molecular interaction maps and therapeutic rationale

19 March 2017

1 reference

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Chk1 and Chk2 kinases in checkpoint control and cancer

19 March 2017

1 reference

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Active and inactive protein kinases: structural basis for regulation

7 April 2017

1 reference

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Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors

7 April 2017

1 reference

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Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs

27 September 2017

1 reference

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ATM signaling and genomic stability in response to DNA damage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

The DNA damage response: sensing and signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Structural modes of stabilization of permissive phosphorylation sites in protein kinases: distinct strategies in Ser/Thr and Tyr kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Determination of substrate specificity and putative substrates of Chk2 kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Chk2 activation and phosphorylation-dependent oligomerization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

CHK2 kinase--a busy messenger.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Two-stage mechanism for activation of the DNA replication checkpoint kinase Cds1 in fission yeast

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

The hCds1 (Chk2)-FHA domain is essential for a chain of phosphorylation events on hCds1 that is induced by ionizing radiation

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601209

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601209

Potent inhibition of checkpoint kinase activity by a hymenialdisine-derived indoloazepine

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601209

Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Discriminating between homodimeric and monomeric proteins in the crystalline state

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500991

Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16794575

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7601209

1 reference

1 reference

1 reference

PubMed publication ID

16794575

1 reference