(Q24294998)

negative regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Qintong Li

4

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author name string

Sarah A Byers

1

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Jason P Price

2

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Jeffrey J Cooper

3

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David H Price

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

22 April 2005

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published in

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volume

280

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page(s)

16360-7

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issue

16

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cites work

P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

1 reference

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Cellular control of gene expression by T-type cyclin/CDK9 complexes

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Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

A highly purified RNA polymerase II elongation control system

21 January 2018

1 reference

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Purification of P-TEFb, a transcription factor required for the transition into productive elongation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500424200

Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500424200

CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

Flavopiridol inhibits P-TEFb and blocks HIV-1 replication

21 January 2018

1 reference

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Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro

21 January 2018

1 reference

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A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

NF-kappaB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter

21 January 2018

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c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500424200

7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

21 January 2018

1 reference

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Identification of a novel isoform of Cdk9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

Identification of multiple cyclin subunits of human P-TEFb

21 January 2018

1 reference

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Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner

21 January 2018

1 reference

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Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

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Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor

21 January 2018

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A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb

21 January 2018

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Cloning and characterization of cDNA copies of the 7S RNAs of HeLa cells

21 January 2018

1 reference

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Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function

21 January 2018

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Identification of a novel cardiac lineage-associated protein(cCLP-1): A candidate regulator of cardiogenesis

21 January 2018

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Structure, expression, and functional characterization of the mouse CLP-1 gene

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Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells

21 January 2018

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Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

Phosphorylation of RNA polymerase II in cardiac hypertrophy: cell enlargement signals converge on cyclin T/Cdk9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

Pharmacogenomic identification of targets for adjuvant therapy with the topoisomerase poison camptothecin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500424200

Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500424200

Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500424200

Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M500424200