(Q24295143)

Journal of Biological Chemistry

GOA release 2020-03-11

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Jiandi Zhang

1

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language of work or name

English

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publication date

23 November 2007

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published in

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volume

282

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issue

47

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page(s)

34356-64

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cites work

Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

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siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

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Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

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Negative control of p53 by Sir2alpha promotes cell survival under stress

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

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Mammalian SIRT1 represses forkhead transcription factors

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IRS-2 pathways integrate female reproduction and energy homeostasis

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Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

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Disruption of IRS-2 causes type 2 diabetes in mice

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Role of IRS-2 in insulin and cytokine signalling

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Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

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Resveratrol inhibits insulin responses in a SirT1-independent pathway

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Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1

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Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans

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Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

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Dynamics of insulin signaling in 3T3-L1 adipocytes. Differential compartmentalization and trafficking of insulin receptor substrate (IRS)-1 and IRS-2.

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Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2.

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Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

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Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway

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SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}

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Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1

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Role of central nervous system and ovarian insulin receptor substrate 2 signaling in female reproductive function in the mouse.

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The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats

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Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

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Extended longevity in mice lacking the insulin receptor in adipose tissue

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The endocrine regulation of aging by insulin-like signals

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.

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Suppression of aging in mice by the hormone Klotho

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The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

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The Sir2 family of protein deacetylases

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Genetics of non-insulin-dependent (type-II) diabetes mellitus

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Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

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Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

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Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth

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SIRT1 regulates HIV transcription via Tat deacetylation

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Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

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DeltaNp63alpha overexpression induces downregulation of Sirt1 and an accelerated aging phenotype in the mouse.

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Identifiers

DOI

10.1074/JBC.M706644200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

17901049

1 reference

Consolidated OpenCitations Corpus – April 2017