(Q24296406)

English

Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2

scientific article published on October 1, 2003

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scholarly article

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Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2 (English)

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Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (English)

1 reference

10.1128/MCB.23.20.7177-7188.2003

https://api.crossref.org/works/10.1128/MCB.23.20.7177-7188.2003

15 March 2024

0 references

ELAV like RNA binding protein 1

1 reference

GOA release 2020-03-11

MAPK activated protein kinase 2

1 reference

GOA release 2020-03-11

3'-UTR-mediated mRNA stabilization

1 reference

GOA release 2020-03-11

surface antigens

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517288

15 March 2024

enzymologic gene expression regulation

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517288

15 March 2024

Fabienne Maurer

2

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1

object named as

Hoanh Tran

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517288

15 March 2024

author name string

Yoshikuni Nagamine

3

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language of work or name

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publication date

October 2003

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full work available at URL

https://mcb.asm.org/content/23/20/7177.full.pdf

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15 March 2024

https://europepmc.org/articles/PMC230330

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Europe PubMed Central

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Europe PubMed Central

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15 March 2024

https://europepmc.org/articles/PMC230330?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517288

15 March 2024

https://doi.org/10.1128/mcb.23.20.7177-7188.2003

online access status

1 reference

Europe PubMed Central

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15 March 2024

https://journals.asm.org/doi/pdf/10.1128/MCB.23.20.7177-7188.2003

1 reference

10.1128/MCB.23.20.7177-7188.2003

https://api.crossref.org/works/10.1128/MCB.23.20.7177-7188.2003

15 March 2024

https://www.tandfonline.com/doi/pdf/10.1128/MCB.23.20.7177-7188.2003

1 reference

10.1128/MCB.23.20.7177-7188.2003

https://api.crossref.org/works/10.1128/MCB.23.20.7177-7188.2003

15 March 2024

Molecular and Cellular Biology

0 references

23

0 references

7177-88

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20

0 references

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1 reference

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AMP-activated kinase regulates cytoplasmic HuR.

1 reference

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19 March 2017

Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock

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Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase

1 reference

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19 March 2017

Protein ligands to HuR modulate its interaction with target mRNAs in vivo

1 reference

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HuR regulates p21 mRNA stabilization by UV light

1 reference

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1 reference

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PRAK, a novel protein kinase regulated by the p38 MAP kinase

1 reference

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Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

1 reference

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1 reference

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1 reference

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MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

1 reference

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19 March 2017

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

1 reference

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19 March 2017

Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2

1 reference

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19 March 2017

Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230330

19 March 2017

AU-rich elements: characterization and importance in mRNA degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230330

7 April 2017

HuR and mRNA stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230330

7 April 2017

RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230330

7 April 2017

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230330

7 April 2017

ARED 2.0: an update of AU-rich element mRNA database.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230330

27 September 2017

Oxidative stress-induced apoptosis in dividing fibroblasts involves activation of p38 MAP kinase and over-expression of Bax: resistance of quiescent cells to oxidative stress

1 reference

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27 September 2017

uPAR: a versatile signalling orchestrator

1 reference

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27 September 2017

Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230330

27 September 2017

Activation of the mitogen-activated protein kinase pathways by heat shock

1 reference

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27 September 2017

Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells

1 reference

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27 September 2017

Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1. Coactivator-associated arginine methyltransferase

1 reference

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Cytoskeletal changes in hypoxic pulmonary endothelial cells are dependent on MAPK-activated protein kinase MK2.

1 reference

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Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR.

1 reference

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27 September 2017

Distinct cellular functions of MK2.

1 reference

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Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA.

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A 40-bp RNA element that mediates stabilization of vascular endothelial growth factor mRNA by HuR.

1 reference

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Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration

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Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology.

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Regulation of mRNA stability in mammalian cells

1 reference

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27 September 2017

The plasminogen activator system: biology and regulation

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27 September 2017

The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.

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Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade

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HuR binding to cytoplasmic mRNA is perturbed by heat shock

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based on heuristic

inferred from PubMed ID database lookup

Cancer Research

46

59

5286

author name string

Montero L.

publication date

1999

1 reference

10.1128/MCB.23.20.7177-7188.2003

https://api.crossref.org/works/10.1128/MCB.23.20.7177-7188.2003

15 March 2024

Cancer Research

62

53

4720

author name string

Walensky L. D.

publication date

1993

1 reference

10.1128/MCB.23.20.7177-7188.2003

https://api.crossref.org/works/10.1128/MCB.23.20.7177-7188.2003

15 March 2024

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