(Q24298665)

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Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling

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Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling (English)

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Lymphocyte protein tyrosine kinase

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GOA release 2020-03-11

Hepatitis C virus

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inferred from title

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9

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Andrew Macdonald

1

object named as

Andrew Macdonald

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object named as

Holly Shelton

8

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Christopher McCormick

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Christopher McCormick

3

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Mark Harris

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author name string

Sabine Mazaleyrat

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Andrew Street

4

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Nicholas J Burgoyne

5

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Richard M Jackson

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Virginie Cazeaux

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language of work or name

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publication date

April 2005

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Journal of General Virology

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86

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Pt 4

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1035-44

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A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein

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7 January 2021

based on heuristic

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Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid refinement of protein interfaces incorporating solvation: application to the docking problem

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https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

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SH3 domains with high affinity and engineered ligand specificities targeted to HIV-1 Nef.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of the ERK1/2 signaling pathway from HCV NS5A protein expressed by herpes simplex recombinant viruses

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

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Global surveillance and control of hepatitis C. Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium

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https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

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NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling

1 reference

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7 January 2021

based on heuristic

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An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

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The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade

1 reference

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7 January 2021

based on heuristic

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The NS5A protein of hepatitis C virus is a zinc metalloprotein

1 reference

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7 January 2021

based on heuristic

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Identification and characterization of amphiphysin II as a novel cellular interaction partner of the hepatitis C virus NS5A protein

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

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The di-leucine motif in the cytoplasmic tail of CD4 is not required for binding to human immunodeficiency virus type 1 Nef, but is critical for CD4 down-modulation

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Introduction of replication-competent hepatitis C virus transcripts using a tetracycline-regulable baculovirus delivery system

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

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The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Hepatitis C virus NS5A: tales of a promiscuous protein

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The identification of conserved interactions within the SH3 domain by alignment of sequences and structures

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

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Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

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Interleukin-1 Inhibits Hepatitis C Virus Subgenomic RNA Replication by Activation of Extracellular Regulated Kinase Pathway

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-function analysis of SH3 domains: SH3 binding specificity altered by single amino acid substitutions

1 reference

https://api.crossref.org/works/10.1099%2FVIR.0.80734-0

7 January 2021

based on heuristic

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Identifiers

10.1099/VIR.0.80734-0

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