(Q40666014)

22 September 2017

The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling (English)

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22 September 2017

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1 reference

Christopher McCormick

4

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22 September 2017

6

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22 September 2017

1

Andrew Macdonald

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author name string

Katherine Crowder

2

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22 September 2017

Andrew Street

3

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22 September 2017

Kalle Saksela

5

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22 September 2017

language of work or name

English

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publication date

5 March 2003

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Journal of Biological Chemistry

22 September 2017

10

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based on heuristic

inferred from page(s)

published in

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22 September 2017

278

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22 September 2017

17775-17784

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22 September 2017

20

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Differential regulation of cyclins D1 and D3 in hepatocyte proliferation.

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Genetic organization and diversity of the hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Replication of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Production of two phosphoproteins from the NS5A region of the hepatitis C viral genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: a potential mechanism of interferon resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

The structure and function of proline-rich regions in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

From receptors to stress-activated MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Molecular interpretation of ERK signal duration by immediate early gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

The regulation of AP-1 activity by mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

The inhibition of cAMP-dependent protein kinase by full-length hepatitis C virus NS3/4A complex is due to ATP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Transforming growth factor-beta1 induces interleukin-6 expression via activating protein-1 consisting of JunD homodimers in primary human lung fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Synergistic activation of NFAT by HIV-1 nef and the Ras/MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Identification of the Nef-associated kinase as p21-activated kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Efficient delivery and regulable expression of hepatitis C virus full-length and minigenome constructs in hepatocyte-derived cell lines using baculovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Hepatitis C virus NS5A protein modulates cell cycle regulatory genes and promotes cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Hepatitis C virus NS5A protein modulates transcription through a novel cellular transcription factor SRCAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Induction of interleukin 6 (IL-6) by hypoxia in vascular cells. Central role of the binding site for nuclear factor-IL-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

21 January 2018

Epidermal Growth Factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Ordered phosphorylation of p42mapk by MAP kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Human immunodeficiency virus type 1 Nef selectively associates with a catalytically active subpopulation of p21-activated kinase 2 (PAK2) independently of PAK2 binding to Nck or beta-PIX

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Hepatitis C virus core protein induces cell proliferation and activates ERK, JNK, and p38 MAP kinases together with the MAP kinase phosphatase MKP-1 in a HepG2 Tet-Off cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Regulation of mRNA Translation and Cellular Signaling by Hepatitis C Virus Nonstructural Protein NS5A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Activation of STAT3 by the Hepatitis C Virus Core Protein Leads to Cellular Transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Cell Cycle-dependent Chronic Infection of Human Cytomegalovirus in Human Osteogenic Sarcoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Reovirus-induced sigma1s-dependent G(2)/M phase cell cycle arrest is associated with inhibition of p34(cdc2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Reoviruses and the host cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

A G1 cell cycle arrest induced by ligands of the reovirus type 3 receptor is secondary to inactivation of p21ras and mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

The ORF3 protein of hepatitis E virus binds to Src homology 3 domains and activates MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serine/threonine kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Induction of activator protein 1 (AP-1) in macrophages by human immunodeficiency virus type-1 NEF is a cell-type-specific response that requires both hck and MAPK signaling events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Lack of negative influence on the cellular transcription factors NF-kappaB and AP-1 by the nef protein of human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Cell transformation by the middle T-antigen of polyoma virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Activation of a ras-MAPK-dependent pathway by Epstein-Barr virus latent membrane protein 1 is essential for cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210900200

21 January 2018

Identifiers

DOI

10.1074/JBC.M210900200

1 reference

22 September 2017

1 reference