(Q24301574)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

TEK receptor tyrosine kinase

21 December 2019

main subject

1 reference

GOA release 2020-03-11

sprouting angiogenesis

1 reference

GOA release 2020-03-11

author

Enrica Audero

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Lucia Napione

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Marco Arese

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Luisa Lanfrancone

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Federico Bussolino

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Ilaria Cascone

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Fabrizio Maniero

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

language of work or name

English

0 references

publication date

9 December 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

number of pages

10

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

13224-13233

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

Molecular mechanisms of blood vessel formation

21 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Vascular-specific growth factors and blood vessel formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Tie receptors: new modulators of angiogenic and lymphangiogenic responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Chemotactic properties of angiopoietin-1 and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Angiopoietin-1 induces sprouting angiogenesis in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Characterization of TEK receptor tyrosine kinase and its ligands, Angiopoietins, in human hematopoietic progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Endothelial receptor tyrosine kinases activate the STAT signaling pathway: mutant Tie-2 causing venous malformations signals a distinct STAT activation response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Signaling via Shc family adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Evolution of Shc functions from nematode to human

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Human endothelial cells expressing polyoma middle T induce tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Functional importance of amino-terminal domain of Shc for interaction with insulin and epidermal growth factor receptors in phosphorylation-independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Insulin signals to prenyltransferases via the Shc branch of intracellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Angiopoietin-1 is an apoptosis survival factor for endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Adaptor protein Shc is an isoform-specific direct activator of the tyrosine kinase c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Shc isoform-specific tyrosine phosphorylation by the insulin and epidermal growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

A cryptic targeting signal induces isoform-specific localization of p46Shc to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Serine/threonine phosphorylation of ShcA. Regulation of protein-tyrosine phosphatase-pest binding and involvement in insulin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

SHC-alpha5beta1 integrin interactions regulate breast cancer cell adhesion and motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Bifurcation of cell migratory and proliferative signaling by the adaptor protein Shc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Regulation of cell motility by mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

The adaptor protein Shc couples a class of integrins to the control of cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

A signaling pathway from the alpha5beta1 and alpha(v)beta3 integrins that elevates bcl-2 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Dynamic modules and heterogeneity of function: a lesson from tyrosine kinase receptors in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Interaction with the Phosphotyrosine Binding Domain/Phosphotyrosine Interacting Domain of SHC Is Required for the Transforming Activity of the FLT4/VEGFR3 Receptor Tyrosine Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Angiopoietin-1 inhibits irradiation- and mannitol-induced apoptosis in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Specificity of the PTB domain of Shc for beta turn-forming pentapeptide motifs amino-terminal to phosphotyrosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

EphB ligand, ephrinB2, suppresses the VEGF- and angiopoietin 1-induced Ras/mitogen-activated protein kinase pathway in venous endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

A novel, microcarrier-based in vitro assay for rapid and reliable quantification of three-dimensional cell migration and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

7 January 2021

New responsibilities for the PI3K regulatory subunit p85 alpha.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

7 January 2021

ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

7 January 2021

Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307456200

7 January 2021

Identifiers

DOI

10.1074/JBC.M307456200

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14665640%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017