(Q42834816)

8 November 2017

A cryptic targeting signal induces isoform-specific localization of p46Shc to mitochondria (English)

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8 November 2017

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1

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8 November 2017

Marco Maccarana

2

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8 November 2017

Veronica A Raker

series ordinal

3

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8 November 2017

Pier Giuseppe Pelicci

series ordinal

4

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8 November 2017

language of work or name

English

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publication date

22 October 2003

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Journal of Biological Chemistry

8 November 2017

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8 November 2017

279

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8 November 2017

3

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8 November 2017

2299-2306

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The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter

8 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Sch proteins are localized on endoplasmic reticulum membranes and are redistributed after tyrosine kinase receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Polypeptide and phospholipid composition of the membrane of rat liver peroxisomes: comparison with endoplasmic reticulum and mitochondrial membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Mitochondrial protein import: two membranes, three translocases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Targeting of pre-ornithine transcarbamylase to mitochondria: definition of critical regions and residues in the leader peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Signaling via Shc family adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Adaptor protein Shc is an isoform-specific direct activator of the tyrosine kinase c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Shc isoform-specific tyrosine phosphorylation by the insulin and epidermal growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Serine/threonine phosphorylation of ShcA. Regulation of protein-tyrosine phosphatase-pest binding and involvement in insulin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Coupling of folding and binding in the PTB domain of the signaling protein Shc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Isoform-specific localization of A-RAF in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Bcl-2 targets the protein kinase Raf-1 to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Mitochondrial targeting of JNK/SAPK in the phorbol ester response of myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Protein phosphorylation in mitochondria from human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

NH2-Terminal targeting motifs direct dual specificity A-kinase-anchoring protein 1 (D-AKAP1) to either mitochondria or endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Novel fluorescent protein from Discosoma coral and its mutants possesses a unique far-red fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Targeting of the c-Abl tyrosine kinase to mitochondria in the necrotic cell death response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

Phosphorylation of mitochondrial proteins in bovine heart. Characterization of kinases and substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307655200

21 January 2018

Identifiers

DOI

10.1074/JBC.M307655200

1 reference

8 November 2017

1 reference